- Synonyms: N-(7-Dimethylamino-4-methylcoumarin-3-yl) maleimide
- Purity: ≥98% (NMR)
- Appearance: Orange solid.
- CAS-Number: 55145-14-7
- Molecular Formula: C16H14N2O4
- Molecular Weight: 298.29
- Identity: 1H-NMR
- Solvents: water
- Melting Point: 218-220 °C
- Fluorescence: λex 398 nm; λem 482 nm in 0.1 M phosphate pH 7.0 (after derivatization with 2-mercaptoethanol)
- Smiles: CN(C)C1=CC=C2C(OC(=O)C(N3C(=O)C=CC3=O)=C2C)=C1
- InChi: InChI=1S/C16H14N2O4/c1-9-11-5-4-10(17(2)3)8-12(11)22-16(21)15(9)18-13(19)6-7-14(18)20/h4-8H,1-3H3
- InChi Key: ADEORFBTPGKHRP-UHFFFAOYSA-N
Available from stock
DACM
SKU: D0047
Category: Fluorescent Detection
- Shipping: AMBIENT
- Short Term Storage: +4°C
- Long Term Storage: -20°C
- Handling Advice: Protect from light and moisture.
- Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.
- Description: Excellent blue fluorescent thiol-reactive reagent (Ex/Em: 383/463nm), widely used for probing configurations of biomolecules such as proteins and create blue-fluorescent bioconjugates. The unreacted reagent is non-fluorescent and can also be used to quantitate free thiols. Shows superior fluorescence and water solubility properties than dansyl chloride.
- References: (1) L. Pollegioni et al.; Arch. of Biochem. Bioph. 343(1), 1 (1997), (2) B. Werneburg et al.; Arch. of Biochem. Bioph. 303(2), 214 (1993), (3) Y. Kanaoka et al.; Angew. Chem. 89, 141 (1977)
Excellent blue fluorescent thiol-reactive reagent (Ex/Em: 383/463nm), widely used for probing configurations of biomolecules such as proteins and create blue-fluorescent bioconjugates. The unreacted reagent is non-fluorescent and can also be used to quantitate free thiols. Shows superior fluorescence and water solubility properties than dansyl chloride.
Additional information
| Melting Point | 218-220 °C |
|---|---|
| Handling Advice | Protect from light and moisture. |
| Identity | 1H-NMR |
| Availability | 1 |
| CAS-Number | 55145-14-7 |
| Fluorescence | λex 398 nm; λem 482 nm in 0.1 M phosphate pH 7.0 (after derivatization with 2-mercaptoethanol) |
| InChi | InChI=1S/C16H14N2O4/c1-9-11-5-4-10(17(2)3)8-12(11)22-16(21)15(9)18-13(19)6-7-14(18)20/h4-8H,1-3H3 |
| Appearance | Orange solid. |
| InChi Key | ADEORFBTPGKHRP-UHFFFAOYSA-N |
| Long Term Storage | -20°C |
| Quantity | 25 mg, 5 mg, Bulk |
| Pricetable | |
| Molecular Formula | |
| References | (1) L. Pollegioni et al.; Arch. of Biochem. Bioph. 343(1), 1 (1997), (2) B. Werneburg et al.; Arch. of Biochem. Bioph. 303(2), 214 (1993), (3) Y. Kanaoka et al.; Angew. Chem. 89, 141 (1977) |
| Shipping | AMBIENT |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Purity | |
| Short Term Storage | +4°C |
| Molecular Weight | |
| Solvents | water |
| Synonyms | N-(7-Dimethylamino-4-methylcoumarin-3-yl) maleimide |
| Smiles | CN(C)C1=CC=C2C(OC(=O)C(N3C(=O)C=CC3=O)=C2C)=C1 |
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