Specifications
- Purity
- ≥97% (NMR)
- Appearance
- Yellow to brown powder
- Identity
- 1H-NMR
Properties
- Solvents
- chloroform
- Melting Point
- 200-203 °C
- Fluorescence
- λex 490 nm, λem 514 nm in 0.1 M Tris pH 8.0, esterase
Available from stock
Desacetylcolchicine d-tartrate
- SKU
- D0270
Category: Phytochemicals
- Synonyms
- Trimethylcolchicinic acid , TMCA , Trimethylcolchicinic acid methyl ether d-tartrate , NSC36354 , NCI 1136 , SKF 250
- 49720-72-1
- CAS-Number
- C20H23NO5 . C4H6O6
- Molecular Formula
- 357.4 . 150.1
- Molecular Weight
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- +4°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at +4°C.
- Hazard statements
- H300
- Precautionary statements
- P264, P301 + P310
- GHS Symbol
- GHS06
- Signal word
- Danger
- RIDADR
- UN1544 6.1
- Transportation
- Excepted Quantities
- Description
- Anticancer colchicine analog. Microtubule polymerization inhibitor. Prevents cell division.
- Smiles
- O[C@H]([C@@H](O)C([O-])=O)C(O)=O.COC1=C(OC)C(OC)=C2C(CC[C@H]([NH3+])C3=CC(=O)C(OC)=CC=C23)=C1
- InChi Key
- JLRWNBXMQCGSEJ-APBURCQWSA-N
- References
- (1) S. Shen, et al.: Oncogene 30, 4544 (2011) , (2) D.C. Stolinsky, et al.: Oncology 33, 151 (1976) , (3) W.F. Noyes, et al.: J. Exp. Med. 106, 555 (1957)
- InChi
- InChI=1S/C20H23NO5.C4H6O6/c1-23-16-8-6-12-13(10-15(16)22)14(21)7-5-11-9-17(24-2)19(25-3)20(26-4)18(11)12
Anticancer colchicine analog. Microtubule polymerization inhibitor. Prevents cell division.
Additional information
| Synonyms | Trimethylcolchicinic acid, TMCA, Trimethylcolchicinic acid methyl ether d-tartrate, NSC36354, NCI 1136, SKF 250 |
|---|---|
| Purity | ≥97% (NMR) |
| Appearance | Yellow to brown powder |
| CAS-Number | 49720-72-1 |
| Molecular Formula | C20H23NO5 . C4H6O6 |
| Molecular Weight | 357.4 . 150.1 |
| Identity | 1H-NMR |
| Solvents | chloroform |
| Melting Point | 200-203 °C |
| Fluorescence | λex 490 nm, λem 514 nm in 0.1 M Tris pH 8.0, esterase |
| Smiles | O[C@H]([C@@H](O)C([O-])=O)C(O)=O.COC1=C(OC)C(OC)=C2C(CC[C@H]([NH3+])C3=CC(=O)C(OC)=CC=C23)=C1 |
| InChi Key | JLRWNBXMQCGSEJ-APBURCQWSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Hazard statements | H300 |
| Precautionary statements | P264, P301 + P310 |
| GHS Symbol | GHS06 |
| Signal word | Danger |
| RIDADR | UN1544 6.1 |
| Transportation | Excepted Quantities |
| References | (1) S. Shen, et al.: Oncogene 30, 4544 (2011), (2) D.C. Stolinsky, et al.: Oncology 33, 151 (1976), (3) W.F. Noyes, et al.: J. Exp. Med. 106, 555 (1957) |
| InChi | InChI=1S/C20H23NO5.C4H6O6/c1-23-16-8-6-12-13(10-15(16)22)14(21)7-5-11-9-17(24-2)19(25-3)20(26-4)18(11)12 |
| Quantity | 5 mg, 25 mg, 100 mg, Bulk |
