Available from stock
Category: Fluorescent Detection
4-(4,5-diphenyl-1H-imidazol-2-yl)benzoyl chloride (DIB-Cl) as reagent for amine labelling was used successfully for derivatization and fluorescence detection of enantiomers of methamphetamin and p-hydroxymethamphetamin, in urine samples. It has also been used for 3,4-Methylendioxy-N-methylamphetamin in blood, morpholine and orther compounds. DIB-Cl as a label was used on fluorescent derivatization some hydroxyl group containing endocrine disruptors, including bisphenol A (BPA), bisphenol B (BPB), bisphenol E (BPE), bisphenol F (BPF) and 4-nonylphenol (4-NP). DIB-Cl showed superior fluorescence intensity (FI) to other commercially available reagents, excellent stability in solution and high reactivity with primary and secondary amines under mild conditions.
| Synonyms | 4-(4,5-Diphenyl-imidazol-2-yl)benzoyl-chloride |
|---|---|
| Purity | ≥95% (HPLC) |
| Appearance | White to off-white powder |
| CAS-Number | 162756-62-9 |
| Molecular Formula | C22H15ClN2O |
| Molecular Weight | 358.82 |
| Identity | 1H-NMR |
| Solvents | acetonitrile |
| Fluorescence | λex 335 nm, λem 420 nm in chloroform (after derivatization with hexylamine) |
| Smiles | ClC(=O)C1=CC=C(C=C1)C1=NC(=C(N1)C1=CC=CC=C1)C1=CC=CC=C1 |
| InChi Key | PHMRAWURTKPWFB-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H315, H319, H335 |
| Precautionary statements | P261, P305 + P351 + P338 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) M. Wada et al.: Anal. Bioanal. Chem. 391(3), 1057 (2008), (2) M. Tomita et al.: Biomed. Chromatogr. 20(12), 1380 (2006), (3) Y. Sun et al.: Analyt. Sci. 17, 697 (2001), (4) O. Al-Dirbashi et al.: J. Chtomatogr. B 712, 105 (1998) |
| InChi | InChI=1S/C22H15ClN2O/c23-21(26)17-11-13-18(14-12-17)22-24-19(15-7-3-1-4-8-15)20(25-22)16-9-5-2-6-10-16/h1-14H,(H,24,25) |
| Quantity | 200 mg, 1 g, Bulk |
4-(N,N-Diethylaminomethyl)-7-methoxy-coumarin 
