DIB-Cl

Specifications

Purity

≥95% (HPLC)

Appearance

White to off-white powder

Identity

1H-NMR

Properties

Solvents

acetonitrile

Fluorescence

λex 335 nm, λem 420 nm in chloroform (after derivatization with hexylamine)

Documentation

Safety Data Sheet (SDS)

CDX D0009 MSDS.pdf

Shipping

AMBIENT

Short Term Storage

+4°C

Long Term Storage

-20°C

Handling Advice

Protect from light and moisture.

Use / Stability

Stable for at least 2 years after receipt when stored at -20°C.

Hazard statements

H315, H319, H335

Precautionary statements

P261, P305 + P351 + P338

GHS Symbol

GHS07

Signal word

Warning

Transportation

Not dangerous goods

Description

4-(4,5-diphenyl-1H-imidazol-2-yl)benzoyl chloride (DIB-Cl) as reagent for amine labelling was used successfully for derivatization and fluorescence detection of enantiomers of methamphetamin and p-hydroxymethamphetamin, in urine samples. It has also been used for 3,4-Methylendioxy-N-methylamphetamin in blood, morpholine and orther compounds. DIB-Cl as a label was used on fluorescent derivatization some hydroxyl group containing endocrine disruptors, including bisphenol A (BPA), bisphenol B (BPB), bisphenol E (BPE), bisphenol F (BPF) and 4-nonylphenol (4-NP). DIB-Cl showed superior fluorescence intensity (FI) to other commercially available reagents, excellent stability in solution and high reactivity with primary and secondary amines under mild conditions.

Smiles

ClC(=O)C1=CC=C(C=C1)C1=NC(=C(N1)C1=CC=CC=C1)C1=CC=CC=C1

InChi Key

PHMRAWURTKPWFB-UHFFFAOYSA-N

References

(1) M. Wada et al.: Anal. Bioanal. Chem. 391(3), 1057 (2008) , (2) M. Tomita et al.: Biomed. Chromatogr. 20(12), 1380 (2006) , (3) Y. Sun et al.: Analyt. Sci. 17, 697 (2001) , (4) O. Al-Dirbashi et al.: J. Chtomatogr. B 712, 105 (1998)

InChi

InChI=1S/C22H15ClN2O/c23-21(26)17-11-13-18(14-12-17)22-24-19(15-7-3-1-4-8-15)20(25-22)16-9-5-2-6-10-16/h1-14H,(H,24,25)