Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- Orange to red powder
- Identity
- 1H-NMR
Properties
- Solvents
- chloroform
Documentation
- Safety Data Sheet (SDS)
- CDX E0013 MSDS_V1.2.pdf
Available from stock
Eosin-5-isothiocyanate
- SKU
- E0013
Categories: Fluorescent Detection, Fluorescent Detection
- Synonyms
- EITC , 5-Isothiocyanato-2-(2,4,5,7-tetrabromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
- 60520-47-0
- CAS-Number
- C21H7Br4NO5S
- Molecular Formula
- 705
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Hazard statements
- H317-H334
- Precautionary statements
- P261-P280-P342 + P311
- GHS Symbol
- GHS08
- Signal word
- Danger
- Transportation
- Excepted Quantities
- Description
- Fluorescent probe. Long wavelength red labeling derivative for proteins. Can be used as a reversible inhibitor of the erythrocyte calcium pump as well as an effective phosphorescent probe in measurement of rotational diffusion of proteins and in fluorescence energy transfer (FRET) studies. EITC tagged molecules may be used together with fluorescein-5?-isothiocyanate (FITC) tagged molecules in fluoresce resonance energy transfer (FRET) based assays. Spectral properties: Abs/Em = 520/544 nm
- Smiles
- OC(=O)C1=C(C=CC(=C1)N=C=S)C1=C2C=C(Br)C(=O)C(Br)=C2OC2=C1C=C(Br)C(O)=C2Br
- InChi Key
- MCXYFYWNOWPDMA-UHFFFAOYSA-N
- References
- (1) E. Nigg, et al.: Biochim. Biophys. Acta 550, 328 (1979) , (2) T. Chiba, et al.: Biochim. Biophys. Acta - Biomembranes 897, 14 (1987) , (3) S. Papp, et al.: Biophys. J. 51, 205 (1987) , (4) R. Wagner, et al.: FEBS Lett. 230, 109 (1988) , (5) R. Wagner, et al.: Eur. J. Biochem. 173, 561 (1988) , (6) D. Ben-Hail, et al.: BBRC 426, 158 (2012)
- InChi
- InChI=1S/C21H7Br4NO5S/c22-12-4-10-14(8-2-1-7(26-6-32)3-9(8)21(29)30)11-5-13(23)18(28)16(25)20(11)31-19(10)15(24)17(12)27/h1-5,27H,(H,29,30)
Fluorescent probe. Long wavelength red labeling derivative for proteins. Can be used as a reversible inhibitor of the erythrocyte calcium pump as well as an effective phosphorescent probe in measurement of rotational diffusion of proteins and in fluorescence energy transfer (FRET) studies. EITC tagged molecules may be used together with fluorescein-5?-isothiocyanate (FITC) tagged molecules in fluoresce resonance energy transfer (FRET) based assays. Spectral properties: Abs/Em = 520/544 nm
Additional information
| Synonyms | EITC, 5-Isothiocyanato-2-(2,4,5,7-tetrabromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | Orange to red powder |
| CAS-Number | 60520-47-0 |
| Molecular Formula | C21H7Br4NO5S |
| Molecular Weight | 705 |
| Identity | 1H-NMR |
| Solvents | chloroform |
| Smiles | OC(=O)C1=C(C=CC(=C1)N=C=S)C1=C2C=C(Br)C(=O)C(Br)=C2OC2=C1C=C(Br)C(O)=C2Br |
| InChi Key | MCXYFYWNOWPDMA-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H317-H334 |
| Precautionary statements | P261-P280-P342 + P311 |
| GHS Symbol | GHS08 |
| Signal word | Danger |
| Transportation | Excepted Quantities |
| References | (1) E. Nigg, et al.: Biochim. Biophys. Acta 550, 328 (1979), (2) T. Chiba, et al.: Biochim. Biophys. Acta – Biomembranes 897, 14 (1987), (3) S. Papp, et al.: Biophys. J. 51, 205 (1987), (4) R. Wagner, et al.: FEBS Lett. 230, 109 (1988), (5) R. Wagner, et al.: Eur. J. Biochem. 173, 561 (1988), (6) D. Ben-Hail, et al.: BBRC 426, 158 (2012) |
| InChi | InChI=1S/C21H7Br4NO5S/c22-12-4-10-14(8-2-1-7(26-6-32)3-9(8)21(29)30)11-5-13(23)18(28)16(25)20(11)31-19(10)15(24)17(12)27/h1-5,27H,(H,29,30) |
| Quantity | 50 mg, 250 mg, Bulk |
