Available from stock
Category: Vitamins
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Folic acid, also known as folate, is a B vitamin is an essential nutritional component of the human diet. It is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis, and for preventing changes to DNA, and consequently cancer. It is especially important during periods of frequent cell division and growth, such as infancy and pregnancy. Folate is needed to carry one-carbon groups for methylation reactions and nucleic acid synthesis. Folic acid deficiency hinders DNA synthesis and cell division, affecting hematopoietic cells and neoplasms the most because of their greater frequency of cell division. Both adults and children need folate to make normal red and white blood cells and prevent anemia. Deficiency of folic acid in pregnant women has been implicated in neural tube defects (NTD).
| Synonyms | PteGlu, Pteroyl-L-glutamic acid, Vitamin M |
|---|---|
| Purity | ≥95% (HPLC) |
| Appearance | Yellow to orange crystalline powder |
| CAS-Number | 59-30-3 |
| Molecular Formula | C19H19N7O6 |
| Molecular Weight | 441.40 |
| Identity | 1H-NMR |
| Solvents | water (1.6 mg/ml), 1 M NaOH (50 mg/ml), methanol (slightly), diluted acids, alkaline solutions |
| Melting Point | 285° C |
| Smiles | O=C(O)[C@](NC(C1=CC=C(NCC2=NC3=C(N=C2)N=C(N)NC3=O)C=C1)=O)([H])CCC(O)=O |
| InChi Key | OVBPIULPVIDEAO-LBPRGKRZSA-N |
| Shipping | AMBIENT |
| Short Term Storage | RT |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Transportation | Not dangerous goods |
| References | B. Kamen, Se≥ Oncol. 24, S18-30 (1997), Y.I. Kim, Nutr. Rev. 57, 314 (1999), S.W. Choi & J.B. Mason, J. Nutr. 130, 129 (2000), P. Mastroiacovo & E. Leoncini, Biofactors 37, 272 (2011), S.Y. Taylor, et al., Eur. J. Pharmacol. 714, 193 (2013), N. Laurieri, et al., PLoS One 9, e96370 (2014), S.Y. Hwang, et al., Int. J. Mol. Med. 36, 1073 (2015), H.N. Moussa, et al., Future Sci. OA. 2, 2 (2016) |
| InChi | InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1 |
| Quantity | 25 g, 100 g, Bulk |
Fisetin
