- ≥90% (TLC)
- White to off-white powder
- water, DMSO
Category: Amino Acids, Peptides, Proteins
GSH-OEt is cellpermeable and has been used to protect cells against radiation damage, oxidants and various toxic compounds including heavy metals. GSH-OEt is a protective agent against cellular damage, such as cataracts and mitochondrial degeneration. It undergoes hydrolysis by intracellular esterases thereby increasing intracellular GSH concentration in many tissues and cell types. Glutathione monoethyl ester may be used to supplement cellular pools of GSH in vitro and in vivo and can prevent ROS formation, neutralize toxic products and block apoptosis pathway. The effect of glutathione (GSH) and glutathione ethyl ester (GSH-OEt) supplementation on GSH homeostasis and exercise-induced oxidative stress was also examined. Glutathione ethyl ester protects against cisplatin-induced ototoxicity in the rat.
Glutathione reduced ethyl ester, γ-Glu-Cys-Gly-OEt, GSH-MEE
White to off-white powder
|Short Term Storage||
|Long Term Storage||
Protect from light and moisture.
|Use / Stability||
Stable for at least 2 years after receipt when stored at -20°C.
Not dangerous goods
(1) M. A. Retamal et al.: PNAS, 103(12), 4475 (2006), (2) C. Leeuwenburgh et al.: J. Nutr. 128(12), 2420 (1998), (3) K.Nishida et al.: Res. Commun. Chem. Pathol. Pharmacol. 82, 49 (1993)
100 mg, 500 mg, 5 g, Bulk