Available from stock

Indigo Carmine

SKU: I0063

Categories: Fluorescent Detection, Fluorescent Detection

Synonyms: Acid Blue 74 , Indigo-5,5'-disulfonic acid disodium salt , Indigocarmine , Amacid Brilliant Blue , CI 73015; 860-22-0
CAS-Number: C₁₆H₈N₂Na₂O₈S₂
Molecular Formula: 466.35
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥95% (UV/Vis)
Appearance: Dark blue powder
Identity: 1H-NMR

Properties

Solvents: water (slightly), ethanol, Soluble in water (10 g/l at 25° C), glycol, and ethanol (3 mg/ml). Insoluble in benzene, and chloroform.

Documentation

Safety Data Sheet (SDS): CDX I0063 MSDS.pdf

Shipping: AMBIENT
Short Term Storage: RT
Long Term Storage: RT
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at RT.

Hazard statements: H302
Precautionary statements: P264, P0270, P301 + P312, P330
GHS Symbol: GHS07
Signal word: Warning
Transportation: Not dangerous goods

Description: Indigo carmine is a blue, anionic indigoid dye consisting of an indigo dimer with sodium salts of sulfonic acids at positions 5 and 5'. This compound has been used as a tissue stain, pH indicator (Blue (at pH11.5) to yellow (at pH14.0)) and tool for the determination of hypochlorite in solutions. It is also applied in detecting microorganisms, treating amyloidosis, in medical devices and drug delivery systems. It can be used as a contrast stain for plasma when red nuclear stains are used. It is widely used in food and cosmetic industry (beverages, chewing gums, candies, drinks, frozen products, sweetener, tablets, sunscreen, skin and hair products) and as an additive or as a dye for cationic cotton fabrics, filters, display devices, inks, toners, paints, photographic material and toys. Spectral Data: Absorption λmax 608nm.
Smiles: O=C(C(C=C(S(=O)([O-])=O)C=C1)=C1N/2)C2=C3C(C(C=C(S(=O)([O-])=O)C=C4)=C4N3)=O.[Na+].[Na+]
InChi Key: KHLVKKOJDHCJMG-QDBORUFSSA-L
References: (1) G.G. Reinle & E.S. Depuy, Cal. State J. Med. 18, 49 (1920) , (2) M. Mortreuil-Langlois, Stain Technol. 37, 175 (1962) , (3) K. Ikeda, et al., Endoscopy 14, 119 (1982) , (4) F.C. Monson, et al., J. Urol. 145, 842 (1991) , (5) M. Lee & R. Sharifi, Urology 47, 783 (1996) , (6) A. Harriram, et al., J. Environ. Sci. Health A Tox. Hazard Subst. Environ. Eng. 3, 1055 (2003) , (7) A.G. Prado, et al., J. Colloid Interface Sci. 277, 43 (2004) , (8) D.P. Hurlstone, et al., Biotech. Histochem. 82, 57 (2007) (Review) , (9) R.W. Sabnis, Handbook of biological dyes and stains (2010) , (10) B.E. Lee, et al., BMC Gastroenterol. 10, 97 (2010) , (11) Y. Ma, et al. , J. Agric. Food Chem. 60, 10867 (2012) , (12) M. Yao, et al., Sci. Rep. 4, 3650 (2014) , (13) A.L. Costa, et al. , Chemistry 21, 12069 (2015)
InChi: InChI=1S/C16H10N2O8S2.2Na/c19-15-9-5-7(27(21,22)23)1-3-11(9)17-13(15)14-16(20)10-6-8(28(24,25)26)2-4-12(10)18-14,,/h1-6,17-18H,(H,21,22,23)(H,24,25,26),,/q,2*+1/p-2/b14-13+,,

Indigo carmine is a blue, anionic indigoid dye consisting of an indigo dimer with sodium salts of sulfonic acids at positions 5 and 5′. This compound has been used as a tissue stain, pH indicator (Blue (at pH11.5) to yellow (at pH14.0)) and tool for the determination of hypochlorite in solutions. It is also applied in detecting microorganisms, treating amyloidosis, in medical devices and drug delivery systems. It can be used as a contrast stain for plasma when red nuclear stains are used. It is widely used in food and cosmetic industry (beverages, chewing gums, candies, drinks, frozen products, sweetener, tablets, sunscreen, skin and hair products) and as an additive or as a dye for cationic cotton fabrics, filters, display devices, inks, toners, paints, photographic material and toys. Spectral Data: Absorption λmax 608nm.

SKU: I0063 Categories: Fluorescent Detection, Fluorescent Detection

Additional information

Additional information

Synonyms	Acid Blue 74, Indigo-5,5'-disulfonic acid disodium salt, Indigocarmine, Amacid Brilliant Blue, CI 73015
Purity	≥95% (UV/Vis)
Appearance	Dark blue powder
CAS-Number	860-22-0
Molecular Formula	C16H8N2Na2O8S2
Molecular Weight	466.35
Identity	1H-NMR
Solvents	water (slightly), ethanol, Soluble in water (10 g/l at 25° C), glycol, and ethanol (3 mg/ml). Insoluble in benzene, and chloroform.
Smiles	O=C(C(C=C(S(=O)([O-])=O)C=C1)=C1N/2)C2=C3C(C(C=C(S(=O)([O-])=O)C=C4)=C4N3)=O.[Na+].[Na+]
InChi Key	KHLVKKOJDHCJMG-QDBORUFSSA-L
Shipping	AMBIENT
Short Term Storage	RT
Long Term Storage	RT
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at RT.
Hazard statements	H302
Precautionary statements	P264, P0270, P301 + P312, P330
GHS Symbol	GHS07
Signal word	Warning
Transportation	Not dangerous goods
References	(1) G.G. Reinle & E.S. Depuy, Cal. State J. Med. 18, 49 (1920), (2) M. Mortreuil-Langlois, Stain Technol. 37, 175 (1962), (3) K. Ikeda, et al., Endoscopy 14, 119 (1982), (4) F.C. Monson, et al., J. Urol. 145, 842 (1991), (5) M. Lee & R. Sharifi, Urology 47, 783 (1996), (6) A. Harriram, et al., J. Environ. Sci. Health A Tox. Hazard Subst. Environ. Eng. 3, 1055 (2003), (7) A.G. Prado, et al., J. Colloid Interface Sci. 277, 43 (2004), (8) D.P. Hurlstone, et al., Biotech. Histochem. 82, 57 (2007) (Review), (9) R.W. Sabnis, Handbook of biological dyes and stains (2010), (10) B.E. Lee, et al., BMC Gastroenterol. 10, 97 (2010), (11) Y. Ma, et al. , J. Agric. Food Chem. 60, 10867 (2012), (12) M. Yao, et al., Sci. Rep. 4, 3650 (2014), (13) A.L. Costa, et al. , Chemistry 21, 12069 (2015)
InChi	InChI=1S/C16H10N2O8S2.2Na/c19-15-9-5-7(27(21,22)23)1-3-11(9)17-13(15)14-16(20)10-6-8(28(24,25)26)2-4-12(10)18-14,,/h1-6,17-18H,(H,21,22,23)(H,24,25,26),,/q,2*+1/p-2/b14-13+,,
Quantity	25 mg, 100 mg, Bulk