Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- White powder
- Identity
- 1H-NMR
Properties
- Solvents
- water (25 mg/ml).
- Melting Point
- 284 °C (decomp.) (lit.)
- Density
- 1.206 g/mL (predicted)
Available from stock
L-Methionine
- SKU
- M0524
Category: Amino Acids, Peptides, Proteins
- Synonyms
- (S)-2-Amino-4-(methylmercapto)butyric acid , L-2-Amino-4-(methylthio)butanoic acid , S-methyl-L-Homocysteine , NSC 22946 , h-Met-oh
- 63-68-3
- CAS-Number
- C5H11NO2S
- Molecular Formula
- 149.21
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- RT
- Long Term Storage
- RT
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at RT.
- Transportation
- Not dangerous goods
- Description
- Essential amino acid involved in various biochemical processes in humans and mammals. Important in angiogenesis, the growth of new blood vessels and supplementation may be beneficial in diseases such as Parkinson's, schizophrenia, asthma or allergies, as well as in radiation, copper poisoning, alcoholism or depressions. Through transmethylation it can be converted to S-adenosylmethionine, a primary methyl donor that methylates compounds to form such products as creatine and phosphatidylcholine. Methionine can be converted to cysteine, a precursor of glutathione and taurine. These molecules may regulate intestinal epithelial oxidative status, and may contribute to intestinal mucosal integrity and gut function. Overconsumption of methionine has been associated to cancer growth. Restriction of methionine can increase lifespans and inhibit cancer growth. Used in livestock nutrition. Apart from its nutritional function, also important for the metabolism and gut health of animals. L-Methionine serves as precursor for transmethylation and transsulphuration. Methionine adenosylation results in the formation of S-adenosyl-L-methionine (SAM). SAM serves as a methyl donor to a number of substances. This methylation is significantly associated with the immune system functioning. Thus, SAM deficiency causes severe combined immunodeficiencies. L-Methionine’s metabolic product, glutathione, is known to regulate immune response and has antiviral action.
- Smiles
- N[C@H](C(O)=O)CCSC
- InChi Key
- FFEARJCKVFRZRR-BYPYZUCNSA-N
- References
- (1) P.J. Garlick, J. Nutr. 136, 1722S (2006) , (2) R. Van Brummelen & D. du Toit, Amino Acids 33, 157 (2007) , (3) J. Gomez, et al., J. Bioenerg. Biomembr. 41, 309 (2009) , (4) A. Karau & I. Grayson, Adv. Biochem. Eng. Biotechnol. 143, 189 (2014)
- InChi
- InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
Essential amino acid involved in various biochemical processes in humans and mammals. Important in angiogenesis, the growth of new blood vessels and supplementation may be beneficial in diseases such as Parkinson’s, schizophrenia, asthma or allergies, as well as in radiation, copper poisoning, alcoholism or depressions. Through transmethylation it can be converted to S-adenosylmethionine, a primary methyl donor that methylates compounds to form such products as creatine and phosphatidylcholine. Methionine can be converted to cysteine, a precursor of glutathione and taurine. These molecules may regulate intestinal epithelial oxidative status, and may contribute to intestinal mucosal integrity and gut function. Overconsumption of methionine has been associated to cancer growth. Restriction of methionine can increase lifespans and inhibit cancer growth. Used in livestock nutrition. Apart from its nutritional function, also important for the metabolism and gut health of animals. L-Methionine serves as precursor for transmethylation and transsulphuration. Methionine adenosylation results in the formation of S-adenosyl-L-methionine (SAM). SAM serves as a methyl donor to a number of substances. This methylation is significantly associated with the immune system functioning. Thus, SAM deficiency causes severe combined immunodeficiencies. L-Methionine’s metabolic product, glutathione, is known to regulate immune response and has antiviral action.
Additional information
| Synonyms | (S)-2-Amino-4-(methylmercapto)butyric acid, L-2-Amino-4-(methylthio)butanoic acid, S-methyl-L-Homocysteine, NSC 22946, h-Met-oh |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | White powder |
| CAS-Number | 63-68-3 |
| Molecular Formula | C5H11NO2S |
| Molecular Weight | 149.21 |
| Identity | 1H-NMR |
| Solvents | water (25 mg/ml). |
| Melting Point | 284 °C (decomp.) (lit.) |
| Density | 1.206 g/mL (predicted) |
| Smiles | N[C@H](C(O)=O)CCSC |
| InChi Key | FFEARJCKVFRZRR-BYPYZUCNSA-N |
| Shipping | AMBIENT |
| Short Term Storage | RT |
| Long Term Storage | RT |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at RT. |
| Transportation | Not dangerous goods |
| References | (1) P.J. Garlick, J. Nutr. 136, 1722S (2006), (2) R. Van Brummelen & D. du Toit, Amino Acids 33, 157 (2007), (3) J. Gomez, et al., J. Bioenerg. Biomembr. 41, 309 (2009), (4) A. Karau & I. Grayson, Adv. Biochem. Eng. Biotechnol. 143, 189 (2014) |
| InChi | InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1 |
| Quantity | 25 g, Bulk |
