Lasalocid A sodium salt

SKU: L0015

Category: Antibiotics

Synonyms: Avatec , Bovatec , MT2007 , NSC243046 , Ro 2-2985 , Lascaloid; 25999-20-6
CAS-Number: C₃₄H₅₃NaO₈
Molecular Formula: 612.77
Molecular Weight

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥97% (NMR)
Identity: 1H-NMR
Appearance: Colorless powder

Properties

Other: pKa: 3.15 (Predicted)
Refractive Index: n20D 1.53 (Predicted)
Melting Point: 180 °C (lit.)
Solvents: ethanol, methanol, DMSO, DMF, water (partly)

Shipping: AMBIENT
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.
Handling Advice: Protect from light and moisture.
Long Term Storage: -20°C
Short Term Storage: +4°C

Transportation: Packing Group III
RIDADR: UN3462 6.1

Description: Ionophore. Potent antibacterial agent and a coccidiostat. Able to form neutral complexes with monovalent and divalent cations and transport them through apolar phase (including lipid bilayer membranes). It can transport also larger organic cations, like protonated dopamine.
InChi: InChI=1S/C34H54O8.Na/c1-9-25(31-21(6)18-34(11-3,42-31)26-16-17-33(40,10-2)23(8)41-26)30(37)22(7)28(35)19(4)12-14-24-15-13-20(5)29(36)27(24)32(38)39 , /h13,15,19,21-23,25-26,28,31,35-36,40H,9-12,14,16-18H2,1-8H3,(H,38,39) , /q , +1/p-1/t19-,21+,22+,23+,25+,26-,28+,31+,33-,34+ , /m1./s1
References: (1) D.J. Patel & C. Shen , PNAS 73, 1786 (1976) , (2) C.C. Chiang & I.C. Paul , Science 196, 1441 (1977) , (3) B. Ehrenberg, et al. , Biophys. Chem. 7, 217 (1977) , (4) G.R. Painter, et al. , Biochemistry 21, 5613 (1982) , (5) R. Fernandez, et al. , Eur. J. Biochem. 167, 353 (1987) , (6) Y.N. Antonenko & L.S. Yaguzhinsky , Biochim. Biophys. Acta 938, 125 (1988) , (7) R.V. Antonio, et al. , Biochim. Biophys. Acta 1056, 250 (1991) , (8) A. Chattopadhyay, et al. , Biochim. Biophys. Acta 1104, 147 (1992)
InChi Key: RDHDUYAKDYQPEW-HWLWSTNVSA-M
Smiles: OC1=C(C)C=CC(CC[C@@H](C)[C@H](O)[C@@H](C([C@@H]([C@]2([H])[C@@H](C)C[C@]([C@]3([H])O[C@@H](C)[C@@](O)(CC)CC3)(CC)O2)CC)=O)C)=C1C([O-])=O.[Na+]

Ionophore. Potent antibacterial agent and a coccidiostat. Able to form neutral complexes with monovalent and divalent cations and transport them through apolar phase (including lipid bilayer membranes). It can transport also larger organic cations, like protonated dopamine.

SKU: L0015 Category: Antibiotics

Additional information

Additional information

Synonyms	Avatec, Bovatec, MT2007, NSC243046, Ro 2-2985, Lascaloid
Purity	≥97% (NMR)
Appearance	Colorless powder
CAS-Number	25999-20-6
Molecular Formula	C34H53NaO8
Molecular Weight	612.77
Identity	1H-NMR
Solvents	ethanol, methanol, DMSO, DMF, water (partly)
Melting Point	180 °C (lit.)
Refractive Index	n20D 1.53 (Predicted)
Other	pKa: 3.15 (Predicted)
Smiles	OC1=C(C)C=CC(CC[C@@H](C)[C@H](O)[C@@H](C([C@@H]([C@]2([H])[C@@H](C)C[C@]([C@]3([H])O[C@@H](C)[C@@](O)(CC)CC3)(CC)O2)CC)=O)C)=C1C([O-])=O.[Na+]
InChi Key	RDHDUYAKDYQPEW-HWLWSTNVSA-M
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
RIDADR	UN3462 6.1
Transportation	Packing Group III
References	(1) D.J. Patel & C. Shen, PNAS 73, 1786 (1976), (2) C.C. Chiang & I.C. Paul, Science 196, 1441 (1977), (3) B. Ehrenberg, et al., Biophys. Chem. 7, 217 (1977), (4) G.R. Painter, et al., Biochemistry 21, 5613 (1982), (5) R. Fernandez, et al., Eur. J. Biochem. 167, 353 (1987), (6) Y.N. Antonenko & L.S. Yaguzhinsky, Biochim. Biophys. Acta 938, 125 (1988), (7) R.V. Antonio, et al., Biochim. Biophys. Acta 1056, 250 (1991), (8) A. Chattopadhyay, et al., Biochim. Biophys. Acta 1104, 147 (1992)
InChi	InChI=1S/C34H54O8.Na/c1-9-25(31-21(6)18-34(11-3,42-31)26-16-17-33(40,10-2)23(8)41-26)30(37)22(7)28(35)19(4)12-14-24-15-13-20(5)29(36)27(24)32(38)39, /h13,15,19,21-23,25-26,28,31,35-36,40H,9-12,14,16-18H2,1-8H3,(H,38,39), /q, +1/p-1/t19-,21+,22+,23+,25+,26-,28+,31+,33-,34+, /m1./s1
Quantity	50 mg, 250 mg, Bulk