Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- Yellowish oily liquid
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO, methanol, ethanol
Category: Lipids, Fatty Acids
Latanoprost is the isopropyl ester of 17-phenyl-13,14-dihydro prostaglandin F2α (17-phenyl-13,14-dihydro PGF2α). It is a prodrug form of the free acid, which is a potent agonist of the FP prostaglandin receptor in the eye. Latanoprost reduces intraocular pressure in glaucoma patients with few side effects.
Synonyms | Xalatan, Isopropyl (5Z,9a,11a,15R)-9,11,15-trihydroxy-17-phenyl-18,19,20-trinor-prost-5-en-1-oate, 17-phenyl-13,14-dihydro trinor Prostaglandin F2α isopropyl ester |
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Purity | ≥98% (HPLC) |
Appearance | Yellowish oily liquid |
CAS-Number | 130209-82-4 |
Molecular Formula | C26H40O5 |
Molecular Weight | 432.59 |
Identity | 1H-NMR |
Solvents | DMSO, methanol, ethanol |
Smiles | O[C@@H]1[C@H](C/C=CCCCC(OC(C)C)=O)[C@@H](CC[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C1 |
InChi Key | GGXICVAJURFBLW-CEYXHVGTSA-N |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Transportation | Not dangerous goods |
References | (1) J. Stjernschantz & B. Resul, Drugs Future 17, 691 (1992), (2) A. Alm, et al., Ophthalmol. 100, 1312 (1993), (3) C.B. Camras, et al., Ophthalmol. 103, 1916 (1996), (4) E. Linden, et al., Br. J. Ophthalmol. 81, 370 (1997), (5) J. Stjernschantz, Invest. Ophthalmol. Vis. Sci. 42, 1134 (2001) (Review), (6) A. Alm, et al., Clin Ophthalmol. 8, 1967 (2014) (Review) |
InChi | InChI=1S/C26H40O5/c1-19(2)31-26(30)13-9-4-3-8-12-22-23(25(29)18-24(22)28)17-16-21(27)15-14-20-10-6-5-7-11-20/h3,5-8,10-11,19,21-25,27-29H,4,9,12-18H2,1-2H3/b8-3-/t21-,22+,23+,24-,25+/m0/s1 |
Quantity | 10 mg, 25 mg, Bulk |