Available from stock

Latanoprost

SKU: L0069

Category: Lipids, Fatty Acids

Synonyms: Xalatan , Isopropyl (5Z,9a,11a,15R)-9,11,15-trihydroxy-17-phenyl-18,19,20-trinor-prost-5-en-1-oate , 17-phenyl-13,14-dihydro trinor Prostaglandin F2α isopropyl ester; 130209-82-4
CAS-Number: C₂₆H₄₀O₅
Molecular Formula: 432.59
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98% (HPLC)
Appearance: Yellowish oily liquid
Identity: 1H-NMR

Properties

Solvents: DMSO, methanol, ethanol

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: -20°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.

Transportation: Not dangerous goods

Description: Latanoprost is the isopropyl ester of 17-phenyl-13,14-dihydro prostaglandin F2α (17-phenyl-13,14-dihydro PGF2α). It is a prodrug form of the free acid, which is a potent agonist of the FP prostaglandin receptor in the eye. Latanoprost reduces intraocular pressure in glaucoma patients with few side effects.
Smiles: O[C@@H]1[C@H](C/C=CCCCC(OC(C)C)=O)[C@@H](CC[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C1
InChi Key: GGXICVAJURFBLW-CEYXHVGTSA-N
References: (1) J. Stjernschantz & B. Resul, Drugs Future 17, 691 (1992) , (2) A. Alm, et al., Ophthalmol. 100, 1312 (1993) , (3) C.B. Camras, et al., Ophthalmol. 103, 1916 (1996) , (4) E. Linden, et al., Br. J. Ophthalmol. 81, 370 (1997) , (5) J. Stjernschantz, Invest. Ophthalmol. Vis. Sci. 42, 1134 (2001) (Review) , (6) A. Alm, et al., Clin Ophthalmol. 8, 1967 (2014) (Review)
InChi: InChI=1S/C26H40O5/c1-19(2)31-26(30)13-9-4-3-8-12-22-23(25(29)18-24(22)28)17-16-21(27)15-14-20-10-6-5-7-11-20/h3,5-8,10-11,19,21-25,27-29H,4,9,12-18H2,1-2H3/b8-3-/t21-,22+,23+,24-,25+/m0/s1

Latanoprost is the isopropyl ester of 17-phenyl-13,14-dihydro prostaglandin F2α (17-phenyl-13,14-dihydro PGF2α). It is a prodrug form of the free acid, which is a potent agonist of the FP prostaglandin receptor in the eye. Latanoprost reduces intraocular pressure in glaucoma patients with few side effects.

SKU: L0069 Category: Lipids, Fatty Acids

Additional information

Additional information

Synonyms	Xalatan, Isopropyl (5Z,9a,11a,15R)-9,11,15-trihydroxy-17-phenyl-18,19,20-trinor-prost-5-en-1-oate, 17-phenyl-13,14-dihydro trinor Prostaglandin F2α isopropyl ester
Purity	≥98% (HPLC)
Appearance	Yellowish oily liquid
CAS-Number	130209-82-4
Molecular Formula	C26H40O5
Molecular Weight	432.59
Identity	1H-NMR
Solvents	DMSO, methanol, ethanol
Smiles	O[C@@H]1[C@H](C/C=CCCCC(OC(C)C)=O)[C@@H](CC[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C1
InChi Key	GGXICVAJURFBLW-CEYXHVGTSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Transportation	Not dangerous goods
References	(1) J. Stjernschantz & B. Resul, Drugs Future 17, 691 (1992), (2) A. Alm, et al., Ophthalmol. 100, 1312 (1993), (3) C.B. Camras, et al., Ophthalmol. 103, 1916 (1996), (4) E. Linden, et al., Br. J. Ophthalmol. 81, 370 (1997), (5) J. Stjernschantz, Invest. Ophthalmol. Vis. Sci. 42, 1134 (2001) (Review), (6) A. Alm, et al., Clin Ophthalmol. 8, 1967 (2014) (Review)
InChi	InChI=1S/C26H40O5/c1-19(2)31-26(30)13-9-4-3-8-12-22-23(25(29)18-24(22)28)17-16-21(27)15-14-20-10-6-5-7-11-20/h3,5-8,10-11,19,21-25,27-29H,4,9,12-18H2,1-2H3/b8-3-/t21-,22+,23+,24-,25+/m0/s1
Quantity	10 mg, 25 mg, Bulk