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    Lucigenin

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      Lucigenin

      SKU
      D0068

      Category: Fluorescent Detection

      Synonyms
      N,N'-Dimethyl-9,9'-biacridinium dinitrate , 9,9'-Bis(N-methylacridinium nitrate)
      2315-97-1
      CAS-Number
      C28H22N4O6
      Molecular Formula
      510.5
      Molecular Weight

      For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥98% (NMR)
      Appearance
      Off-white to brown powder
      Identity
      1H-NMR

      Properties

      Solvents
      acetic acid (10 mg/ml), water (slightly), DMSO
      Fluorescence
      λex 550 nm, λem 369 nm
      Shipping
      AMBIENT
      Short Term Storage
      +4°C
      Long Term Storage
      +4°C
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at +4°C.
      Transportation
      Not dangerous goods
      Description
      Chemiluminescent probe for the detection of peroxides in biological systems. Reagent used for the generation of chemiluminescence in the presence of a reductant and oxygen It is employed in numerous chemiluminescent assays. Lucigenin is specific for superoxide anion radical.
      Smiles
      C[N+]1=C2C=CC=CC2=C(C2=CC=CC=C12)C1=C2C=CC=CC2=[N+](C)C2=C1C=CC=C2
      InChi Key
      FULGIHLPACFUCU-UHFFFAOYSA-N
      References
      (1) M. Kervinen et al.: Anal. Biochem. 324(1), 45 (2004) , (2) M. Kanemitsu et al.: Anal. Chim. Acta 403(1-2), 125 (2000) , (3) L.J. Kricka et al.: Methods Enzymol. 305, 333 (2000) , (4) K. Faulkner et al.: Free Radic. Biol. Med. 15, 447 (1993) , (5) A. Ingvarsson et al.: Anal. Chem. 60, 2047 (1988) , (6) P. Corbisier et al.: J. Anal. Biochem. 164(1), 240 (1987)
      InChi
      InChI=1S/C28H22N2/c1-29-23-15-7-3-11-19(23)27(20-12-4-8-16-24(20)29)28-21-13-5-9-17-25(21)30(2)26-18-10-6-14-22(26)28/h3-18H,1-2H3/q+2

      Chemiluminescent probe for the detection of peroxides in biological systems. Reagent used for the generation of chemiluminescence in the presence of a reductant and oxygen It is employed in numerous chemiluminescent assays. Lucigenin is specific for superoxide anion radical.

      SKU: D0068 Category: Fluorescent Detection
      • Additional information

      Additional information

      Synonyms

      N,N'-Dimethyl-9,9'-biacridinium dinitrate, 9,9'-Bis(N-methylacridinium nitrate)

      Purity

      ≥98% (NMR)

      Appearance

      Off-white to brown powder

      CAS-Number

      2315-97-1

      Molecular Formula

      C28H22N4O6

      Molecular Weight

      510.5

      Identity

      1H-NMR

      Solvents

      acetic acid (10 mg/ml), water (slightly), DMSO

      Fluorescence

      λex 550 nm, λem 369 nm

      Smiles

      C[N+]1=C2C=CC=CC2=C(C2=CC=CC=C12)C1=C2C=CC=CC2=[N+](C)C2=C1C=CC=C2

      InChi Key

      FULGIHLPACFUCU-UHFFFAOYSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      +4°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at +4°C.

      Transportation

      Not dangerous goods

      References

      (1) M. Kervinen et al.: Anal. Biochem. 324(1), 45 (2004), (2) M. Kanemitsu et al.: Anal. Chim. Acta 403(1-2), 125 (2000), (3) L.J. Kricka et al.: Methods Enzymol. 305, 333 (2000), (4) K. Faulkner et al.: Free Radic. Biol. Med. 15, 447 (1993), (5) A. Ingvarsson et al.: Anal. Chem. 60, 2047 (1988), (6) P. Corbisier et al.: J. Anal. Biochem. 164(1), 240 (1987)

      InChi

      InChI=1S/C28H22N2/c1-29-23-15-7-3-11-19(23)27(20-12-4-8-16-24(20)29)28-21-13-5-9-17-25(21)30(2)26-18-10-6-14-22(26)28/h3-18H,1-2H3/q+2

      Quantity

      2 g, 10 g, Bulk

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