Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- Light yellow powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO (5 mg/ml), DMF (2 mg/ml)
Category: Phytochemicals
Mangiferin is a xanthone glucoside that has been found in M. indica with diverse biological activities, including analgesic, antidiabetic, antisclerotic, antimicrobial and antiviral, cardio-, hepato-, and neuroprotective, anti-inflammatory, immunomodulatory, anticancer, as well as radioprotective against X-ray, gamma and UV radiation effects. It is also used in cosmetics, due to antioxidant and UV-protecting properties. The anti-inflammatroy activity is through inhibiting NF-?B and NLRP3 signaling pathways.
Synonyms | MGF, 1,3,6,7-Tetrahydroxyxanthone C2-β-D-glucoside, NSC 248870 |
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Purity | ≥98% (HPLC) |
Appearance | Light yellow powder |
CAS-Number | 4773-96-0 |
Molecular Formula | C19H18O11 |
Molecular Weight | 422.34 |
Identity | 1H-NMR |
Solvents | DMSO (5 mg/ml), DMF (2 mg/ml) |
Smiles | OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](C2=C(O)C(C(C(C=C(O)C(O)=C3)=C3O4)=O)=C4C=C2O)O1 |
InChi Key | AEDDIBAIWPIIBD-ZJKJAXBQSA-N |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Hazard statements | H302 |
Precautionary statements | P301 + P312 + P330 |
GHS Symbol | GHS07 |
Signal word | Warning |
Transportation | Not dangerous goods |
References | (1) F. Gold-Smith, et al., Nutrients 8, E396 (2016) (Review), (2) S. Saha, et al., Biofactors 42, 459 (2016) (Review), (3) A.J. Nunez Selles, et al., Biofactors 42, 475 (2016) (Review), (4) E.V. Fomenko & Y. Chi, Biofactors 42, 492 (2016) (Review), (5) M. Imran, et al., Lipids Health Dis. 16, 84 (2017) (Review), (6) S. Du, et al., Mol. Med. Rep. 18, 4775 (2018) (Review), (7) F. Quadri, et al., Expert Opin. Ther. Pat. 29, 463 (2019) (Review), (8) S.T. Feng, et al., Pharmacol. Res. 146, 104336 (2019) (Review) |
InChi | InChI=1S/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19+/m1/s1 |
Quantity | 1 g, Bulk |