Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- White to beige powder
- Identity
- 1H-NMR
Properties
- Solvents
- water (20 mg/ml)
- Melting Point
- 99-101 °C (lit.)
Mepivacaine hydrochloride is a long-acting local anesthetic that reversibly blocks transient Na+ inward current, as well as the steady-state K+ outward current. Mepivacaine blocks tandem pore (TASK) and Kv1.5 potassium channels in model systems.
Synonyms | 1-Methyl-2',6'-pipecoloxylidine hydrochloride, N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide hydrochloride, (±)-Mepivacaine hydrochloride |
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Purity | ≥98% (HPLC) |
Appearance | White to beige powder |
CAS-Number | 1722-62-9 |
Molecular Formula | C15H22N2O . HCl |
Molecular Weight | 282.81 |
Identity | 1H-NMR |
Solvents | water (20 mg/ml) |
Melting Point | 99-101 °C (lit.) |
Smiles | CC1=CC=CC(C)=C1NC(C2N(C)CCCC2)=O.Cl |
InChi Key | RETIMRUQNCDCQB-UHFFFAOYSA-N |
Shipping | AMBIENT |
Short Term Storage | RT |
Long Term Storage | RT |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at RT. |
Hazard statements | H301 |
Precautionary statements | P301 + P310 |
GHS Symbol | GHS06 |
Signal word | Danger |
RIDADR | UN2811 |
Transportation | Packing Group III |
References | (1) F.P. Luduena, et al., Toxicol. Appl. Pharmacol. 2, 295 (1960), (2) M. Sadove & G.D. Wessinger, J. Int. Coll. Surg. 34, 573 (1960), (3) A. El-Maghraby, et al., J. Egypt Med. Assoc. 47, 153 (1964), (4) A.G. Burm, et al., Anesth. Analg. 84, 85 (1997), (5) V. Tagariello, et al., Minerva Anestesiol. 67, 5 (2001) (Review), (6) A. Leffler, et al., Eur. J. Pharmacol. 630, 19 (2010), (7) W.G. Brockmann, Gen. Dent. 62, 70 (2014) (Review) |
InChi | InChI=1S/C15H22N2O.ClH/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3,/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18),1H |
Quantity | 50 mg, Bulk |