Methsuximide
- SKU
- M0153
Category: API's & Intermediates
- Synonyms
- Mesuximide , 1,3-Dimethyl-3-phenyl-2,5-pyrrolidinedione , 1,3-Dimethyl-3-phenylsuccinimide , PM 396
- 77-41-8
- CAS-Number
- C12H13NO2
- Molecular Formula
- 203.24
- Molecular Weight
Specifications
- Purity
- ≥98% (GC)
- Appearance
- White powder
- Identity
- 1H-NMR
Properties
- Solvents
- chloroform, methanol, DMSO
- Melting Point
- 52 - 53 °C
- Boiling Point
- 346.4±31.0 °C at 760 mmHg
- Refractive Index
- 1.552
Downloads
- Safety Data Sheet
- CDX M0153 MSDS.pdf
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Hazard statements
- H302-H412
- Precautionary statements
- P301 + P312 + P330
- GHS Symbol
- GHS07
- Signal word
- Warning
- Transportation
- Not dangerous goods
- Description
- A succinimide with anti-epileptic and anti-convulsant properties. The mechanisms of action are unknown and possibly multiple. Metabolically reduced to it's pharmacologically active metabolite N-desmethylmethosuximide.
- Smiles
- O=C(C(C1=CC=CC=C1)(C)C2)N(C)C2=O
- InChi Key
- AJXPJJZHWIXJCJ-UHFFFAOYSA-N
- References
- (1) C.A. Miller, et al.: JACS 73, 4895 (1951) , (2) C.A. Miller, et al.: JACS 73, 5608 (1951) , (3) G. Chen, et al.: Epilepsia 4, 66 (1963) , (4) J.M. Strong, et al.: Neurology 24, 250 (1974) , (5) T.R. Browne, et al.: Neurology 33, 414 (1983)
- InChi
- InChI=1S/C12H13NO2/c1-12(9-6-4-3-5-7-9)8-10(14)13(2)11(12)15/h3-7H,8H2,1-2H3
A succinimide with anti-epileptic and anti-convulsant properties. The mechanisms of action are unknown and possibly multiple. Metabolically reduced to it’s pharmacologically active metabolite N-desmethylmethosuximide.