• Home
Results for {phrase} ({results_count} of {results_count_total})
Displaying {results_count} results of {results_count_total}

More results...

Filter by Product categories
Bioactive Molecules
Amino Acids, Peptides, Proteins
Carbohydrates
Lipids, Fatty Acids
Metabolites
Phytochemicals
Vitamins
Bioactive Small Molecules
Biopolymers
Detection in Bioanalysis
Fluorescent Detection
Organic Pollutants & Pesticides
Fungicides
Herbicides
Insecticides
Other Pollutants
Pharmaceutically Actives
Antibiotics
API's & Intermediates
Steroids
Reagents and Building Blocks
Reagents for Life Sciences
Buffers
Building Blocks, Intermediates, Reagents
Fluorescent Detection
Linker
Non Fluorescent Detection & Chromogene Detection
Quorum Sensing
Uncategorized
    Industriestrasse 15, CH-9015 St. Gallen, Tel: +41 71 244 48 25
    • 0Shopping Cart
    Chemodex
    • Home
    • Products
    • Catalogs
    • About Chemodex
    • Contact & Distributors
    • Menu Menu
    Moxifloxacin hydrochloride

    Available from stock

      Inquiry

      Please fill out the form for your inquiry:



      * required field

      Moxifloxacin hydrochloride

      SKU
      M0189

      Category: Antibiotics

      Synonyms
      BAY 12-8039 , Alelox , 1-Cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydropyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
      186826-86-8
      CAS-Number
      C21H24FN3O4· HCl
      Molecular Formula
      401.43 . 36.46
      Molecular Weight

      For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥97% (NMR)
      Appearance
      Light yellow powder
      Identity
      1H-NMR

      Properties

      Solvents
      DMSO (10 mg/ml), water (5 mg/ml)

      Documentation

      Safety Data Sheet (SDS)
      CDX M0189 MSDS.pdf
      Shipping
      AMBIENT
      Short Term Storage
      +4°C
      Long Term Storage
      -20°C
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at -20°C.
      Transportation
      Not dangerous goods
      Description
      Moxifloxacin is a fourth-generation synthetic broad-spectrum fluoroquinolone antibiotic. It is used against both Gram-positive and Gram-negative bacteria and to treat bacterial infections associated with bronchitis, sinusitis, and other conditions. Fluoroquinolones stabilize DNA strand breaks created by DNA gyrase (Topo II) and topoisomerase IV by binding to the enzyme-DNA complex. Compared to mammalian DNA gyrase, moxifloxacin has 100 times higher affinity for bacterial DNA gyrase. Can also be used as reference compound.
      Smiles
      O=C1C(C(O)=O)=CN(C2CC2)C3=C(OC)C([NH+]4C[C@](NCCC5)([H])[C@]5([H])C4)=C(F)C=C31.[Cl-]
      InChi Key
      IDIIJJHBXUESQI-DFIJPDEKSA-N
      References
      (1) M. Souli, et al., Int. J. Antimicrob. Agents. 10, 23 (1998) , (2) C. Ballow, et al., Clin. Ther. 21, 513 (1999) , (3) A. Dalhoff, et al., Clin. Infect. Dis. 32, S22 (2001) , (4) R. Kishii, et al., Antimicrob. Agents Chemother. 47, 77 (2003) , (5) M. Miravitlles, J. Chron. Obstruct. Pulmon. Dis. 2, 191 (2007) , (6) M. Miravitlles & A. Anzueto, Expert Opin. Pharmacother. 9, 1755 (2008) (Review) , (7) H. Takiff & E. Guerrero, Antimicrob. Agents Chemother. 55, 5421 (2011) , (8) M.M. Al Omari, et al., Profiles Drug Subst. Excip. Relat. Methodol. 39, 299 (2014) (Review)
      InChi
      InChI=1S/C21H24FN3O4.ClH/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24 , /h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28) , 1H/t11-,16+ , /m0./s1

      Moxifloxacin is a fourth-generation synthetic broad-spectrum fluoroquinolone antibiotic. It is used against both Gram-positive and Gram-negative bacteria and to treat bacterial infections associated with bronchitis, sinusitis, and other conditions. Fluoroquinolones stabilize DNA strand breaks created by DNA gyrase (Topo II) and topoisomerase IV by binding to the enzyme-DNA complex. Compared to mammalian DNA gyrase, moxifloxacin has 100 times higher affinity for bacterial DNA gyrase. Can also be used as reference compound.

      SKU: M0189 Category: Antibiotics
      • Additional information

      Additional information

      Synonyms

      BAY 12-8039, Alelox, 1-Cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydropyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride

      Purity

      ≥97% (NMR)

      Appearance

      Light yellow powder

      CAS-Number

      186826-86-8

      Molecular Formula

      C21H24FN3O4· HCl

      Molecular Weight

      401.43 . 36.46

      Identity

      1H-NMR

      Solvents

      DMSO (10 mg/ml), water (5 mg/ml)

      Smiles

      O=C1C(C(O)=O)=CN(C2CC2)C3=C(OC)C([NH+]4C[C@](NCCC5)([H])[C@]5([H])C4)=C(F)C=C31.[Cl-]

      InChi Key

      IDIIJJHBXUESQI-DFIJPDEKSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      -20°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at -20°C.

      Transportation

      Not dangerous goods

      References

      (1) M. Souli, et al., Int. J. Antimicrob. Agents. 10, 23 (1998), (2) C. Ballow, et al., Clin. Ther. 21, 513 (1999), (3) A. Dalhoff, et al., Clin. Infect. Dis. 32, S22 (2001), (4) R. Kishii, et al., Antimicrob. Agents Chemother. 47, 77 (2003), (5) M. Miravitlles, J. Chron. Obstruct. Pulmon. Dis. 2, 191 (2007), (6) M. Miravitlles & A. Anzueto, Expert Opin. Pharmacother. 9, 1755 (2008) (Review), (7) H. Takiff & E. Guerrero, Antimicrob. Agents Chemother. 55, 5421 (2011), (8) M.M. Al Omari, et al., Profiles Drug Subst. Excip. Relat. Methodol. 39, 299 (2014) (Review)

      InChi

      InChI=1S/C21H24FN3O4.ClH/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24, /h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28), 1H/t11-,16+, /m0./s1

      Quantity

      50 mg, Bulk

      Related products

      • Flumequine

        Flumequine

        Purity: ≥97% (HPLC)CAS-Number: 42835-25-6SKU: F0079

        Read more Show Details
      • Tamoxifen

        Tamoxifen

        Purity: ≥98% (NMR)CAS-Number: 10540-29-1SKU: T0200

        Read more Show Details
      • Selamectin

        Selamectin

        Purity: ≥99% (HPLC)CAS-Number: 220119-17-5SKU: S0051

        Read more Show Details
      • Lasalocid A sodium salt solution

        Lasalocid A sodium salt solution, ~100 µg/ml in acetonitrile

        Purity: ≥97%CAS-Number: 25999-20-6SKU: L0515

        Read more Show Details
      © Copyright - Chemodex AG - Customized Molecules developed in Switzerland
      • Home
      • All products
      • Order and delivery information
      • Disclaimer
      • Privacy policy
      • About this site
      MagnololMagnololMeptyldinocapMeptyldinocap Scroll to top