Specifications
- Purity
- ≥97% (NMR)
- Appearance
- White to off-white powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO (20mg/ml), DMF (20mg/ml), acetonitrile
Category: Quorum Sensing
N-3-hydroxydecanoyl-L-homoserine lactone is a small diffusible signaling molecule secreted by various bacteria and involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. This lactone is produced via lactonolysis from 3-oxodecanoyl-homoserine lactone, altering quorum sensing or contributing to quorum quenching. The applications of this molecule include regulation of virulence and exoproteases.
Synonyms | OH-C10-HSL, 3-Hydroxy-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-decanamide |
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Purity | ≥97% (NMR) |
Appearance | White to off-white powder |
CAS-Number | 192883-12-8 |
Molecular Formula | C14H25NO4 |
Molecular Weight | 271.3558 |
Identity | 1H-NMR |
Solvents | DMSO (20mg/ml), DMF (20mg/ml), acetonitrile |
Smiles | O=C1[C@@H](NC(CC(O)CCCCCCC)=O)CCO1 |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Transportation | Not dangerous goods |
References | (1) P. Lumjiaktase, et al., Microbiol. 152, 3651 (2006), (2) A. Fekete, et al., Anal. Bioanal. Chem. 387, 455 (2007), (3) X. Chen, et al., Anal. Bioanal. Chem. 398, 2655 (2010), (4) K.G. Chan, et al., BMC Microbiol. 11, 1 (2011), (5) C.W. Ha, et al.: Mol. Cells 33, 53 (2012) |
InChi | InChI=1S/C14H25NO4/c1-2-3-4-5-6-7-11(16)10-13(17)15-12-8-9-19-14(12)18/h11-12,16H,2-10H2,1H3,(H,15,17)/t11?,12-/m0/s1 |
Quantity | 5 mg, 25 mg, Bulk |