Available from stock

N-(3-Hydroxydecanoyl)-L-homoserine lactone

SKU: H0086

Category: Quorum Sensing

Synonyms: OH-C10-HSL , 3-Hydroxy-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-decanamide; 192883-12-8
CAS-Number: C₁₄H₂₅NO₄
Molecular Formula: 271.3558
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥97% (NMR)
Appearance: White to off-white powder
Identity: 1H-NMR

Properties

Solvents: DMSO (20mg/ml), DMF (20mg/ml), acetonitrile

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: -20°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.

Transportation: Not dangerous goods

Description: N-3-hydroxydecanoyl-L-homoserine lactone is a small diffusible signaling molecule secreted by various bacteria and involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. This lactone is produced via lactonolysis from 3-oxodecanoyl-homoserine lactone, altering quorum sensing or contributing to quorum quenching. The applications of this molecule include regulation of virulence and exoproteases.
Smiles: O=C1[C@@H](NC(CC(O)CCCCCCC)=O)CCO1
References: (1) P. Lumjiaktase, et al., Microbiol. 152, 3651 (2006) , (2) A. Fekete, et al., Anal. Bioanal. Chem. 387, 455 (2007) , (3) X. Chen, et al., Anal. Bioanal. Chem. 398, 2655 (2010) , (4) K.G. Chan, et al., BMC Microbiol. 11, 1 (2011) , (5) C.W. Ha, et al.: Mol. Cells 33, 53 (2012)
InChi: InChI=1S/C14H25NO4/c1-2-3-4-5-6-7-11(16)10-13(17)15-12-8-9-19-14(12)18/h11-12,16H,2-10H2,1H3,(H,15,17)/t11?,12-/m0/s1

N-3-hydroxydecanoyl-L-homoserine lactone is a small diffusible signaling molecule secreted by various bacteria and involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. This lactone is produced via lactonolysis from 3-oxodecanoyl-homoserine lactone, altering quorum sensing or contributing to quorum quenching. The applications of this molecule include regulation of virulence and exoproteases.

SKU: H0086 Category: Quorum Sensing

Additional information

Additional information

Synonyms	OH-C10-HSL, 3-Hydroxy-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-decanamide
Purity	≥97% (NMR)
Appearance	White to off-white powder
CAS-Number	192883-12-8
Molecular Formula	C14H25NO4
Molecular Weight	271.3558
Identity	1H-NMR
Solvents	DMSO (20mg/ml), DMF (20mg/ml), acetonitrile
Smiles	O=C1[C@@H](NC(CC(O)CCCCCCC)=O)CCO1
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Transportation	Not dangerous goods
References	(1) P. Lumjiaktase, et al., Microbiol. 152, 3651 (2006), (2) A. Fekete, et al., Anal. Bioanal. Chem. 387, 455 (2007), (3) X. Chen, et al., Anal. Bioanal. Chem. 398, 2655 (2010), (4) K.G. Chan, et al., BMC Microbiol. 11, 1 (2011), (5) C.W. Ha, et al.: Mol. Cells 33, 53 (2012)
InChi	InChI=1S/C14H25NO4/c1-2-3-4-5-6-7-11(16)10-13(17)15-12-8-9-19-14(12)18/h11-12,16H,2-10H2,1H3,(H,15,17)/t11?,12-/m0/s1
Quantity	5 mg, 25 mg, Bulk