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    N-(3-Hydroxytetradecanoyl)-L-homoserine lactone

    Available from stock

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      N-(3-Hydroxytetradecanoyl)-L-homoserine lactone

      SKU
      H0088

      Category: Quorum Sensing

      Synonyms
      3OH-C14-HSL , N-(3-Hydroxytetradecanoyl)-L-homoserine lactone
      364749-99-5
      CAS-Number
      C18H33NO4
      Molecular Formula
      327.46
      Molecular Weight

      For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥96% (HPLC)
      Appearance
      White to off-white powder
      Identity
      1H-NMR

      Properties

      Solvents
      DMF, acetonitrile.
      Shipping
      AMBIENT
      Short Term Storage
      +4°C
      Long Term Storage
      -20°C
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at -20°C.
      Hazard statements
      H301
      Precautionary statements
      P301 + P310
      GHS Symbol
      GHS06
      Signal word
      Danger
      RIDADR
      UN2811 6.1
      Transportation
      Excepted Quantities
      Description
      N-(3-Hydroxytetradecanoyl)-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.
      Smiles
      O=C1OCC[C@H]1NC(CC(O)CCCCCCCCCCC)=O
      InChi Key
      IKQUESGRCDRZTI-OEMAIJDKSA-N
      References
      (1) J. Liu, et al., Front. Microbiol. 8, 1097 (2017) , (2) B.L. Mellbye, et al., Appl. Environ. Microbiol. 83, e01540-17 (2017) , (3) T. Morohoshi, et al., Biosci. Biotech. Biochem. (Epub ahead of print) (2018)
      InChi
      InChI=1S/C18H33NO4/c1-2-3-4-5-6-7-8-9-10-11-15(20)14-17(21)19-16-12-13-23-18(16)22/h15-16,20H,2-14H2,1H3,(H,19,21)

      N-(3-Hydroxytetradecanoyl)-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.

      SKU: H0088 Category: Quorum Sensing
      • Additional information

      Additional information

      Synonyms

      3OH-C14-HSL, N-(3-Hydroxytetradecanoyl)-L-homoserine lactone

      Purity

      ≥96% (HPLC)

      Appearance

      White to off-white powder

      CAS-Number

      364749-99-5

      Molecular Formula

      C18H33NO4

      Molecular Weight

      327.46

      Identity

      1H-NMR

      Solvents

      DMF, acetonitrile.

      Smiles

      O=C1OCC[C@H]1NC(CC(O)CCCCCCCCCCC)=O

      InChi Key

      IKQUESGRCDRZTI-OEMAIJDKSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      -20°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at -20°C.

      Hazard statements

      H301

      Precautionary statements

      P301 + P310

      GHS Symbol

      GHS06

      Signal word

      Danger

      RIDADR

      UN2811 6.1

      Transportation

      Excepted Quantities

      References

      (1) J. Liu, et al., Front. Microbiol. 8, 1097 (2017), (2) B.L. Mellbye, et al., Appl. Environ. Microbiol. 83, e01540-17 (2017), (3) T. Morohoshi, et al., Biosci. Biotech. Biochem. (Epub ahead of print) (2018)

      InChi

      InChI=1S/C18H33NO4/c1-2-3-4-5-6-7-8-9-10-11-15(20)14-17(21)19-16-12-13-23-18(16)22/h15-16,20H,2-14H2,1H3,(H,19,21)

      Quantity

      20 mg, 250 mg, Bulk

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