Specifications
- Purity
- ≥97% (GC)
- Appearance
- White solid
- Identity
- 1H-NMR
Properties
- Solvents
- chloroform
Available from stock
N-(3-Oxobutanoyl)-L-homoserine lactone
- SKU
- O0037
Category: Quorum Sensing
- Synonyms
- 3-oxo-C4-HSL , 3-oxo-N-[(3S)-Tetrahydro-2-oxo-3-furanyl]-butanamide
- 148433-27-6
- CAS-Number
- C8H11NO4
- Molecular Formula
- 185.2
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Transportation
- Not dangerous goods
- Description
- N-(3-Oxobutanoyl)-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.
- Smiles
- [H][C@@]1(CCOC1=O)NC(=O)CC(C)=O
- InChi Key
- FIHPLICEAUNEFV-LURJTMIESA-N
- References
- (1) A. Eberhard, et al.: Arch. Microbiol. 146, 35 (1986) , (2) M.K. Winson, et al.: PNAS 92, 9427 (1995) , (3) A.L. Schaefer, et al.: J. Bacteriol. 178, 2897 (1996) , (4) K.H. McClean, et. al.: Microbiol. 143, 3703 (1997) , (5) J. Zhu, et al.: J. Bacteriol. 180, 5398 (1998) , (6) C. Nantasenamat, et al.: J. Biol. Syst. 16, 279 (2008)
- InChi
- InChI=1S/C8H11NO4/c1-5(10)4-7(11)9-6-2-3-13-8(6)12/h6H,2-4H2,1H3,(H,9,11)/t6-/m0/s1
N-(3-Oxobutanoyl)-L-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.
Additional information
| Synonyms | 3-oxo-C4-HSL, 3-oxo-N-[(3S)-Tetrahydro-2-oxo-3-furanyl]-butanamide |
|---|---|
| Purity | ≥97% (GC) |
| Appearance | White solid |
| CAS-Number | 148433-27-6 |
| Molecular Formula | C8H11NO4 |
| Molecular Weight | 185.2 |
| Identity | 1H-NMR |
| Solvents | chloroform |
| Smiles | [H][C@@]1(CCOC1=O)NC(=O)CC(C)=O |
| InChi Key | FIHPLICEAUNEFV-LURJTMIESA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Transportation | Not dangerous goods |
| References | (1) A. Eberhard, et al.: Arch. Microbiol. 146, 35 (1986), (2) M.K. Winson, et al.: PNAS 92, 9427 (1995), (3) A.L. Schaefer, et al.: J. Bacteriol. 178, 2897 (1996), (4) K.H. McClean, et. al.: Microbiol. 143, 3703 (1997), (5) J. Zhu, et al.: J. Bacteriol. 180, 5398 (1998), (6) C. Nantasenamat, et al.: J. Biol. Syst. 16, 279 (2008) |
| InChi | InChI=1S/C8H11NO4/c1-5(10)4-7(11)9-6-2-3-13-8(6)12/h6H,2-4H2,1H3,(H,9,11)/t6-/m0/s1 |
| Quantity | 10 mg, 100 mg, Bulk |
