Specifications
- Purity
- ≥98% (NMR)
- Identity
- 1H-NMR
- Appearance
- White powder
Properties
- Solvents
- DMSO, dimethylformamide (approx. 30mg/ml)
Available from stock
N-Octanoyl-L-homoserine lactone
- SKU
- O0038
Category: Quorum Sensing
- Synonyms
- N-[(3S)-Tetrahydro-2-oxo-3-furanyl]-octanamide , C8-HSL , OHL
- 147852-84-4
- CAS-Number
- C12H21NO3
- Molecular Formula
- 227.3
- Molecular Weight
- Short Term Storage
- +4°C
- Use / Stability
- Stable for at least 2 years after receipt when stored at +4°C.
- Handling Advice
- Protect from light and moisture.
- Long Term Storage
- +4°C
- Shipping
- AMBIENT
- Transportation
- Not dangerous goods
- Description
- N-Octanoyl-L-homoserine lactone (C8-HSL) is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. The applications of this molecule include infection prevention and regulation of virulence in general and in cystic fibrosis.
- InChi
- InChI=1S/C12H21NO3/c1-2-3-4-5-6-7-11(14)13-10-8-9-16-12(10)15/h10H,2-9H2,1H3,(H,13,14)/t10-/m0/s1
- References
- (1) J.T. Hodgkinson: Tetrahedron Lett. 52, 3291 (2011) , (2) G.D. Geske: JACS 127, 12762 (2005) , (3) A. Kuo, et al.: J. Bacteriol. 176, 7558 (1994) , (4) J.K. Lithgow, et al.: Mol. Microbiol. 37, 81 (2000) , (5) K.H. McClean, et al.: Microbiol. 143, 3703 (1997) , (6) K. Riedel, et al.: Microbiol. 147, 3249 (2001) , (7) M.K. Winson, et al.: PNAS 92, 9427 (1995)
- InChi Key
- JKEJEOJPJVRHMQ-JTQLQIEISA-N
- Smiles
- CCCCCCCC(=O)N[C@H]1CCOC1=O
N-Octanoyl-L-homoserine lactone (C8-HSL) is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. The applications of this molecule include infection prevention and regulation of virulence in general and in cystic fibrosis.
Additional information
| Synonyms | N-[(3S)-Tetrahydro-2-oxo-3-furanyl]-octanamide, C8-HSL, OHL |
|---|---|
| Purity | ≥98% (NMR) |
| Appearance | White powder |
| CAS-Number | 147852-84-4 |
| Molecular Formula | C12H21NO3 |
| Molecular Weight | 227.3 |
| Identity | 1H-NMR |
| Solvents | DMSO, dimethylformamide (approx. 30mg/ml) |
| Smiles | CCCCCCCC(=O)N[C@H]1CCOC1=O |
| InChi Key | JKEJEOJPJVRHMQ-JTQLQIEISA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Transportation | Not dangerous goods |
| References | (1) J.T. Hodgkinson: Tetrahedron Lett. 52, 3291 (2011), (2) G.D. Geske: JACS 127, 12762 (2005), (3) A. Kuo, et al.: J. Bacteriol. 176, 7558 (1994), (4) J.K. Lithgow, et al.: Mol. Microbiol. 37, 81 (2000), (5) K.H. McClean, et al.: Microbiol. 143, 3703 (1997), (6) K. Riedel, et al.: Microbiol. 147, 3249 (2001), (7) M.K. Winson, et al.: PNAS 92, 9427 (1995) |
| InChi | InChI=1S/C12H21NO3/c1-2-3-4-5-6-7-11(14)13-10-8-9-16-12(10)15/h10H,2-9H2,1H3,(H,13,14)/t10-/m0/s1 |
| Quantity | 5 mg, 50 mg, Bulk |
