Specifications
- Purity
- ≥98% (T)
- Appearance
- Off-white to beige powder
- Identity
- 1H-NMR
Properties
- Solvents
- water (20mg/ml), organic solvents (insoluble)
Category: Building Blocks, Intermediates, Reagents
A glycine-phosphonic acid compound, negatively charged at neutral pH, with immunomodulatory and anti-diabetic properties. Enhances anti-B:9-23 TCR-dependent T cell activation by modulating murine class II MHC I-Ag7-mediated B:9-23 presentation on APCs. Daily administration of glyphosine is shown to delay the onset of diabetes in NOD mice. Herbicide. A plant growth regulator. Acts as a competitive inhibitor of phoshoenolpyruvate carboxylase in plants.
Synonyms | N-(Carboxymethyl)iminodi(methylphosphinic acid), Glyphosine, Glycine-N,N-bis(methylenephosphonic acid), BRN 1884944, Polaris |
---|---|
Purity | ≥98% (T) |
Appearance | Off-white to beige powder |
CAS-Number | 2439-99-8 |
Molecular Formula | C4H11NO8P2 |
Molecular Weight | 263.08 |
Identity | 1H-NMR |
Solvents | water (20mg/ml), organic solvents (insoluble) |
Smiles | O=P(O)(O)CN(CP(O)(O)=O)CC(O)=O |
InChi Key | OXHDYFKENBXUEM-UHFFFAOYSA-N |
Shipping | AMBIENT |
Short Term Storage | RT |
Long Term Storage | +4°C |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
Hazard statements | H318 |
Precautionary statements | P280-P305 + P351 + P338 |
GHS Symbol | GHS05 |
Signal word | Danger |
RIDADR | UN3261 8 |
Transportation | Packing Group III |
References | (1) F.E. Podesta, et al., Plant Cell Physiol. 28, 375 (1987), (2) M. Galanski, et al., J. Med. Chem. 46, 4946 (2003), (3) B.D. Stadinski, et al., PNAS 107, 10978 (2010), (4) A.W. Michels, et al., J. Immunol. 187, 5921 (2011) |
Quantity | 10 g, 50 g, Bulk |