• Home
Search

Results for {phrase} ({results_count} of {results_count_total})

Displaying {results_count} results of {results_count_total}

More results...

Generic filters
Filter by Product categories
Bioactive Molecules
Amino Acids, Peptides, Proteins
Carbohydrates
Lipids, Fatty Acids
Metabolites
Phytochemicals
Vitamins
Bioactive Small Molecules
Biopolymers
Detection in Bioanalysis
Fluorescent Detection
Organic Pollutants & Pesticides
Fungicides
Herbicides
Insecticides
Other Pollutants
Pharmaceutically Actives
Antibiotics
API's & Intermediates
Steroids
Reagents and Building Blocks
Reagents for Life Sciences
Buffers
Building Blocks, Intermediates, Reagents
Fluorescent Detection
Linker
Non Fluorescent Detection & Chromogene Detection
Quorum Sensing
Uncategorized
    Industriestrasse 15, CH-9015 St. Gallen, Tel: +41 71 244 48 25
    • 0Shopping Cart
    Chemodex
    • Home
    • Products
    • Catalogs
    • About Chemodex
    • Contact & Distributors
    • Menu Menu
    Paclitaxel

    Available from stock

      Inquiry

      Please fill out the form for your inquiry:



      * required field

      Paclitaxel

      SKU
      P0188

      Category: Antibiotics

      Synonyms
      Taxol , BMS 181339-01 , NSC 125973
      33069-62-4
      CAS-Number
      C47H51NO14
      Molecular Formula
      853.91
      Molecular Weight

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥98%
      Identity
      IR
      Appearance
      White to off-white powder

      Properties

      Solvents
      DMSO (50 mg/ml), methanol (50 mg/ml), ethanol

      Downloads

      Safety Data Sheet
      CDX P0188 MSDS.pdf
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at +4°C.
      Long Term Storage
      +4°C
      Short Term Storage
      +4°C
      Shipping
      AMBIENT
      Transportation
      Not dangerous goods
      Signal word
      Danger
      GHS Symbol
      GHS08
      Precautionary statements
      P201-P260-P280-P308 + P313
      Hazard statements
      H341-H360-H371-H413
      Description
      Anticancer compound. Chemotherapeutic used in patients with cancer and advanced forms of Kaposi's sarcoma. Microtubule assembly stabilizer. Reversibly binds to polymerized tubulin. Mitotic spindle assembly, chromosome segregation and cell division inhibitor. Induces cell cycle arrest at the G2/M phase. Apoptosis inducer through aberrant activation of cyclin-dependent kinases (CKDs) and the c-Jun N-terminal kinase/stress activated protein kinase (JNK/SAPK). Immunosuppressor, immunostimulant and TRAIL sensitizer.
      InChi
      InChI=1S/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33-46(38,24-58-33)62-27(3)50)39(53)37(59-26(2)49)34(25)44(47,4)5/h7-21,31-33,35-38,40,51-52,57H,22-24H2,1-6H3,(H,48,54)/t31-,32-,33+,35-,36+,37+,38-,40-,45+,46-,47+/m0/s1
      References
      (1) J.E. Liebmann, et al., Br. J. Cancer 68, 1104 (1993) , (2) R. Foa, et al., Int. J. Clin. Lab. Res. 24, 6 (1994) (Review) , (3) M. Woods, et al., Mol. Med. 1, 506 (1995) , (4) A. Jordan, et al., Med. Res. Rev. 18, 259 (1998) , (5) L.A. Amos & J. Löwe, Chem. Biol. 6, R65 (1999) (Review) , (6) M.V. Blagosklonny & T. Fojo, Int. J. Cancer 83, 151 (1999) , (7) T.H. Wang, et al., J. Biol. Chem. 274, 8208 (1999) , (8) T.H. Wang, et al., Cancer 88, 2619 (2000) , (9) T.M. Mekhail & M. Markman, Expert Opin. Pharmacother. 3, 755 (2002) , (10) A. Javeed, et al., Eur. J. Pharm. Sci. 38, 283 (2009) (Review) , (11) D. Finlay, et al.,PLoS One 5, e13375 (2010) , (12) B. Ai, et al., Am. J. Cancer Res. 6, 1624 (2016) (Review)
      InChi Key
      RCINICONZNJXQF-MZXODVADSA-N
      Smiles
      O[C@](C(C)(C)C1=C(C)[C@H]2OC([C@@H]([C@H](C3=CC=CC=C3)NC(C4=CC=CC=C4)=O)O)=O)(C2)[C@H]([C@]([C@]([C@@H](O)C5)(C)C([C@@H]1OC(C)=O)=O)([H])[C@]6([C@]5([H])OC6)OC(C)=O)OC(C7=CC=CC=C7)=O

      Anticancer compound. Chemotherapeutic used in patients with cancer and advanced forms of Kaposi’s sarcoma. Microtubule assembly stabilizer. Reversibly binds to polymerized tubulin. Mitotic spindle assembly, chromosome segregation and cell division inhibitor. Induces cell cycle arrest at the G2/M phase. Apoptosis inducer through aberrant activation of cyclin-dependent kinases (CKDs) and the c-Jun N-terminal kinase/stress activated protein kinase (JNK/SAPK). Immunosuppressor, immunostimulant and TRAIL sensitizer.

      SKU: P0188 Category: Antibiotics
      • Additional information

      Additional information

      Synonyms

      Taxol, BMS 181339-01, NSC 125973

      Purity

      ≥98%

      Appearance

      White to off-white powder

      CAS-Number

      33069-62-4

      Molecular Formula

      C47H51NO14

      Molecular Weight

      853.91

      Identity

      IR

      Solvents

      DMSO (50 mg/ml), methanol (50 mg/ml), ethanol

      Smiles

      O[C@](C(C)(C)C1=C(C)[C@H]2OC([C@@H]([C@H](C3=CC=CC=C3)NC(C4=CC=CC=C4)=O)O)=O)(C2)[C@H]([C@]([C@]([C@@H](O)C5)(C)C([C@@H]1OC(C)=O)=O)([H])[C@]6([C@]5([H])OC6)OC(C)=O)OC(C7=CC=CC=C7)=O

      InChi Key

      RCINICONZNJXQF-MZXODVADSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      +4°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at +4°C.

      Hazard statements

      H341-H360-H371-H413

      Precautionary statements

      P201-P260-P280-P308 + P313

      GHS Symbol

      GHS08

      Signal word

      Danger

      Transportation

      Not dangerous goods

      References

      (1) J.E. Liebmann, et al., Br. J. Cancer 68, 1104 (1993), (2) R. Foa, et al., Int. J. Clin. Lab. Res. 24, 6 (1994) (Review), (3) M. Woods, et al., Mol. Med. 1, 506 (1995), (4) A. Jordan, et al., Med. Res. Rev. 18, 259 (1998), (5) L.A. Amos & J. Löwe, Chem. Biol. 6, R65 (1999) (Review), (6) M.V. Blagosklonny & T. Fojo, Int. J. Cancer 83, 151 (1999), (7) T.H. Wang, et al., J. Biol. Chem. 274, 8208 (1999), (8) T.H. Wang, et al., Cancer 88, 2619 (2000), (9) T.M. Mekhail & M. Markman, Expert Opin. Pharmacother. 3, 755 (2002), (10) A. Javeed, et al., Eur. J. Pharm. Sci. 38, 283 (2009) (Review), (11) D. Finlay, et al.,PLoS One 5, e13375 (2010), (12) B. Ai, et al., Am. J. Cancer Res. 6, 1624 (2016) (Review)

      InChi

      InChI=1S/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33-46(38,24-58-33)62-27(3)50)39(53)37(59-26(2)49)34(25)44(47,4)5/h7-21,31-33,35-38,40,51-52,57H,22-24H2,1-6H3,(H,48,54)/t31-,32-,33+,35-,36+,37+,38-,40-,45+,46-,47+/m0/s1

      Quantity

      10 mg, 50 mg, Bulk

      Related products

      • Guanidine thiocyanate

        Guanidine thiocyanate

        Purity: ≥99% (Titration)CAS-Number: 593-84-0SKU: G0058

        Read more Show Details
      • Moxifloxacin hydrochloride

        Moxifloxacin hydrochloride

        Purity: ≥97% (NMR)CAS-Number: 186826-86-8SKU: M0189

        Read more Show Details
      • Lasalocid A sodium salt solution

        Lasalocid A sodium salt solution, ~100 µg/ml in acetonitrile

        Purity: ≥97%CAS-Number: 25999-20-6SKU: L0515

        Read more Show Details
      • Artemisinin

        Artemisinin

        Purity: ≥95% (HPLC)CAS-Number: 63968-64-9SKU: A0335

        Read more Show Details
      © Copyright - Chemodex Ltd. - Customized Molecules developed in Switzerland
      • Home
      • All products
      • Order and delivery information
      • Disclaimer
      • Privacy policy
      • About this site
      (±)-Potassium citramalate monohydrate (±)-Potassium citramalate monohydrate Paeoniflorin Paeoniflorin Scroll to top