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      Silymarin

      SKU
      S0289

      Category: Phytochemicals

      Synonyms
      Mixture of flavanonolderivates Silibinin, Isosilibinin, Silicristin and Silidianin.
      65666-07-1
      CAS-Number
      n/a
      Molecular Formula
      n/a
      Molecular Weight

      For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥30% (HPLC Silybin)
      Appearance
      Yellow to brown powder
      Identity
      1H-NMR

      Properties

      Solvents
      DMSO, ethanol (1 mg/ml)

      Documentation

      Safety Data Sheet (SDS)
      CDX S0289 MSDS.pdf
      Shipping
      AMBIENT
      Short Term Storage
      -20°C
      Long Term Storage
      -20°C
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at -20°C.
      Hazard statements
      H315, H319, H335
      Precautionary statements
      P264, P280, P362+364, P261
      GHS Symbol
      GHS07
      Signal word
      Warning
      Transportation
      Not dangerous goods
      Description
      Silymarin is a polyphenolic flavonoid extracted from the seeds of Silybum marianum or milk thistle. Silymarin is an isomeric mixture of the flavonolignans silydianin, silychristin, silibinin [Silybin] and isosilybin. It has similar biological properties to its main component Silibinin, including potent antioxidant, anti-inflammatory, anticancer, antidiabetic, hepatoprotective, neuroprotective, cardioprotective, antiviral, antimicrobial and immunosuppressive activities.
      References
      (1) N. Skottova & V. Krecman, Physiol. Res. 47, 1 (1998) (Review) , (2) R.P. Singh & R. Agarwal, Antioxid. Redox Signal. 4, 655 (2002) (Review) , (3) S.K. Katiyar, Int. J. Oncol. 26, 169 (2005) (Review) , (4) K.E. Mayer, et al., J. Viral. Hepat. 12, 559 (2005) (Review) , (5) R. Agarwal, et al., Anticancer Res. 26, 4457 (2006) (Review) , (6) K. Ramasamy & R. Agarwal, Cancer Lett. 269, 352 (2008) (Review) , (7) M. Rafieian-Kopaie & H. Nasri, J. Renal Inj. Prev. 1, 3 (2012) (Review) , (8) S.J. Polyak, et al., Hepatology 57, 1262 (2013) (Review) , (9) A. Borah, et al., CNS Neurosci. Ther. 19, 847 (2013) (Review) , (10) P.F. Surai, Antioxidants 4, 204 (2015) (Review) , (11) L. Voroneanu, et al., J. Diabetes Res. 2016, 5147468 (2016) (Review) , (12) K.P. Devi, et al., Curr. Drug Targets 18, 1529 (2017) (Review) , (13) N. Esmaeil, et al., Int. Immunopharmacol. 50, 194 (2017) (Review) , (14) M. Vahabzadeh, et al., J. Sci. Food Agric. 98, 4816 (2018) (Review) , (15) T. Hosseinabadi, et al., Phytother. Res. 33, 2849 (2019) (Review)

      Silymarin is a polyphenolic flavonoid extracted from the seeds of Silybum marianum or milk thistle. Silymarin is an isomeric mixture of the flavonolignans silydianin, silychristin, silibinin [Silybin] and isosilybin. It has similar biological properties to its main component Silibinin, including potent antioxidant, anti-inflammatory, anticancer, antidiabetic, hepatoprotective, neuroprotective, cardioprotective, antiviral, antimicrobial and immunosuppressive activities.

      SKU: S0289 Category: Phytochemicals
      • Additional information

      Additional information

      Synonyms

      Mixture of flavanonolderivates Silibinin, Isosilibinin, Silicristin and Silidianin.

      Purity

      ≥30% (HPLC Silybin)

      Appearance

      Yellow to brown powder

      CAS-Number

      65666-07-1

      Molecular Formula

      n/a

      Molecular Weight

      n/a

      Identity

      1H-NMR

      Solvents

      DMSO, ethanol (1 mg/ml)

      Shipping

      AMBIENT

      Short Term Storage

      -20°C

      Long Term Storage

      -20°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at -20°C.

      Hazard statements

      H315, H319, H335

      Precautionary statements

      P264, P280, P362+364, P261

      GHS Symbol

      GHS07

      Signal word

      Warning

      Transportation

      Not dangerous goods

      References

      (1) N. Skottova & V. Krecman, Physiol. Res. 47, 1 (1998) (Review), (2) R.P. Singh & R. Agarwal, Antioxid. Redox Signal. 4, 655 (2002) (Review), (3) S.K. Katiyar, Int. J. Oncol. 26, 169 (2005) (Review), (4) K.E. Mayer, et al., J. Viral. Hepat. 12, 559 (2005) (Review), (5) R. Agarwal, et al., Anticancer Res. 26, 4457 (2006) (Review), (6) K. Ramasamy & R. Agarwal, Cancer Lett. 269, 352 (2008) (Review), (7) M. Rafieian-Kopaie & H. Nasri, J. Renal Inj. Prev. 1, 3 (2012) (Review), (8) S.J. Polyak, et al., Hepatology 57, 1262 (2013) (Review), (9) A. Borah, et al., CNS Neurosci. Ther. 19, 847 (2013) (Review), (10) P.F. Surai, Antioxidants 4, 204 (2015) (Review), (11) L. Voroneanu, et al., J. Diabetes Res. 2016, 5147468 (2016) (Review), (12) K.P. Devi, et al., Curr. Drug Targets 18, 1529 (2017) (Review), (13) N. Esmaeil, et al., Int. Immunopharmacol. 50, 194 (2017) (Review), (14) M. Vahabzadeh, et al., J. Sci. Food Agric. 98, 4816 (2018) (Review), (15) T. Hosseinabadi, et al., Phytother. Res. 33, 2849 (2019) (Review)

      Quantity

      25 g, 50 g, 100 g, Bulk

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