Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- White powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO, DMF, ethanol, methanol Inwater
- Melting Point
- 118° C
Documentation
- Safety Data Sheet (SDS)
- CDX S0293 MSDS.pdf
Available from stock
Spinosyn A
- SKU
- S0293
Category: Insecticides
- Synonyms
- A-83543A , Lepicidin A
- 131929-60-7
- CAS-Number
- C41H65NO10
- Molecular Formula
- 731.95
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- +4°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at +4°C.
- Hazard statements
- H410
- Precautionary statements
- P273-P391-P501
- GHS Symbol
- GHS09
- Signal word
- Warning
- RIDADR
- UN3077
- Transportation
- Packing Group III
- Description
- Spinosyn A is a naturally-occurring macrocyclic lactone that is a potent insecticide. It is the main component of Spinosad working as a larvicide but also has activity on adult insects and eggs. It is active on Lepdioptera, Thysanoptera, Hymenoptera, Diptera and Coleoptera. It acts as an agonist of insect nicotinic acetylcholinesterase receptors (nAChRs), which differ both structurally and functionally from nAChRs in vertebrates. As a result, it has low affinity for vertebrate nAChRs and has limited adverse effects in those animals. This agent can be used as a reference compound.
- Smiles
- O=C(C[C@]1([H])C2=C[C@]3([H])[C@]1([H])C=C[C@@]4([H])[C@@]3([H])C[C@H](O[C@]5([H])O[C@@H](C)[C@H](OC)[C@@H](OC)[C@H]5OC)C4)O[C@@H](CC)CCC[C@H](O[C@]6([H])O[C@H](C)[C@@H](N(C)C)CC6)[C@@H](C)C2=O
- InChi Key
- SRJQTHAZUNRMPR-IRXCAFTDSA-N
- References
- (1) L.C. Creemer, et al., J. Antibiot. 53, 171 (2000) , (2) D.J. Mergott, et al., PNAS 101, 11955 (2004) , (3) S.O. Duke, et al., Toxins 2, 1943 (2010) , (4) D.T. Vo, et al., J. Vet. Pharmacol. Ther. 33, 315 (2010) , (5) T.S. Amaral, et al., Braz. J. Biol. 72, 299 (2012)
- InChi
- InChI=1S/C41H65NO10/c1-10-26-12-11-13-34(52-36-17-16-33(42(5)6)23(3)48-36)22(2)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(47-9)39(46-8)38(45-7)24(4)49-41/h14-15,20,22-31,33-34,36,38-41H,10-13,16-19,21H2,1-9H3/t22-,23-,24+,25-,26+,27-,28+,29-,30-,31+,33+,34+,36+,38+,39-,40-,41+/m1/s1
Spinosyn A is a naturally-occurring macrocyclic lactone that is a potent insecticide. It is the main component of Spinosad working as a larvicide but also has activity on adult insects and eggs. It is active on Lepdioptera, Thysanoptera, Hymenoptera, Diptera and Coleoptera. It acts as an agonist of insect nicotinic acetylcholinesterase receptors (nAChRs), which differ both structurally and functionally from nAChRs in vertebrates. As a result, it has low affinity for vertebrate nAChRs and has limited adverse effects in those animals. This agent can be used as a reference compound.
Additional information
| Synonyms | A-83543A, Lepicidin A |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | White powder |
| CAS-Number | 131929-60-7 |
| Molecular Formula | C41H65NO10 |
| Molecular Weight | 731.95 |
| Identity | 1H-NMR |
| Solvents | DMSO, DMF, ethanol, methanol Inwater |
| Melting Point | 118° C |
| Smiles | O=C(C[C@]1([H])C2=C[C@]3([H])[C@]1([H])C=C[C@@]4([H])[C@@]3([H])C[C@H](O[C@]5([H])O[C@@H](C)[C@H](OC)[C@@H](OC)[C@H]5OC)C4)O[C@@H](CC)CCC[C@H](O[C@]6([H])O[C@H](C)[C@@H](N(C)C)CC6)[C@@H](C)C2=O |
| InChi Key | SRJQTHAZUNRMPR-IRXCAFTDSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Hazard statements | H410 |
| Precautionary statements | P273-P391-P501 |
| GHS Symbol | GHS09 |
| Signal word | Warning |
| RIDADR | UN3077 |
| Transportation | Packing Group III |
| References | (1) L.C. Creemer, et al., J. Antibiot. 53, 171 (2000), (2) D.J. Mergott, et al., PNAS 101, 11955 (2004), (3) S.O. Duke, et al., Toxins 2, 1943 (2010), (4) D.T. Vo, et al., J. Vet. Pharmacol. Ther. 33, 315 (2010), (5) T.S. Amaral, et al., Braz. J. Biol. 72, 299 (2012) |
| InChi | InChI=1S/C41H65NO10/c1-10-26-12-11-13-34(52-36-17-16-33(42(5)6)23(3)48-36)22(2)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(47-9)39(46-8)38(45-7)24(4)49-41/h14-15,20,22-31,33-34,36,38-41H,10-13,16-19,21H2,1-9H3/t22-,23-,24+,25-,26+,27-,28+,29-,30-,31+,33+,34+,36+,38+,39-,40-,41+/m1/s1 |
| Quantity | 100 mg, 1 g, Bulk |
