Sulforhodamine 101
- SKU
- S0025
Category: Fluorescent Detection, Fluorescent Detection
- Synonyms
- SR 101 , Sulforhodamine 640
- 60311-02-6
- CAS-Number
- C31H30N2O7S2
- Molecular Formula
- 606.71
- Molecular Weight
Specifications
- Purity
- ≥99% (HPLC)
- Appearance
- Green crystalline
- Identity
- 1H-NMR
Properties
- Solvents
- water, methanol (1 mg/ml), ethanol, DMSO, DMF
- Fluorescence
- λex 582-588 nm, λem 601-609 nm in Buffer pH 7 , λex 586 nm, λem 605 nm in H2O
Downloads
- Safety Data Sheet
- CDX S0025 MSDS.pdf
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Transportation
- Not dangerous goods
- Description
- Sulforhodamine 101 is a non-fixable red fluorescent dye used as a specific marker for astrocytes and an activity-dependent probe for monitoring regulated exocytosis. In addition to labeling astrocytes, it also labels myelinating oligodendrocytes. Has been reported to affect excitability of neurons and should therefore be used with caution. Key precursor used for preparing rhodamine 101 sulfonyl chloride (also called Texas Red). Spectral data: λex 586 nm| λem 605 nm in H2O and λex 582-588 nm| λem 601-609 nm in pH7 buffer.
- Smiles
- O=S(C(C=C1)=CC(S(=O)([O-])=O)=C1C(C2=CC(CCCN3CCC4)=C3C4=C2O5)=C6C5=C(CCC7)C8=[N+]7CCCC8=C6)(O)=O
- InChi Key
- COIVODZMVVUETJ-UHFFFAOYSA-N
- References
- (1) W. Ulrich , Biotech. Histochem. 67, 73 (1992) , (2) H.H. Engelhard , Biotech. Histochem. 72, 1 (1997) , (3) A. Nimmerjahn, et al.: Nat. Methods 1, 31 (2004) , (4) A. Nimmerjahn & F. Helmchen , Cold Spring Harb. Protoc. 2012, 326 (2012) , (5) J. Kang, et al.: Neuroscience 169, 1601 (2010) , (6) R.A. Hill & J. Grutzendler , Nat. Methods 11, 1081 (2014)
- InChi
- InChI=1S/C31H30N2O7S2/c34-41(35,36)20-9-10-21(26(17-20)42(37,38)39)27-24-15-18-5-1-11-32-13-3-7-22(28(18)32)30(24)40-31-23-8-4-14-33-12-2-6-19(29(23)33)16-25(27)31/h9-10,15-17H,1-8,11-14H2,(H-,34,35,36,37,38,39)
Sulforhodamine 101 is a non-fixable red fluorescent dye used as a specific marker for astrocytes and an activity-dependent probe for monitoring regulated exocytosis. In addition to labeling astrocytes, it also labels myelinating oligodendrocytes. Has been reported to affect excitability of neurons and should therefore be used with caution. Key precursor used for preparing rhodamine 101 sulfonyl chloride (also called Texas Red). Spectral data: λex 586 nm| λem 605 nm in H2O and λex 582-588 nm| λem 601-609 nm in pH7 buffer.