Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- White to off-white powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO, chloroform
Available from stock
Thiamethoxam-d3
- SKU
- T0142
Category: Building Blocks, Intermediates, Reagents
- Synonyms
- 3-(2-Chloro-5-thiazolylmethyl)tetrahydro-5-methyl-d3-N-nitro-4H-1,3,5-oxadiazin-4-imine
- 1294048-82-0
- CAS-Number
- C8D3H7ClN5O3S
- Molecular Formula
- 294.73
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Hazard statements
- H228,H302,H361fd,H410
- Precautionary statements
- P202 - P210 - P240 - P273 - P301 + P312 - P308 + P313
- GHS Symbol
- GHS02+GHS07+08+09
- Signal word
- Danger
- RIDADR
- UN1325
- Transportation
- Packing Group II
- Description
- Thiamethoxam-d3 is deuterium labelled Thiamethoxam, which is a neonicotinoid insecticide. Neonicotinoids (NNIs) are a family of active substances used in plant protection to control harmful insects and also in veterinary medicine. Neonicotinoids act selectively on the insect nicotinic acetylcholine receptors (nAChRs), initially stimulating postsynaptic receptors, increasing Na+ ingress and K+ egress and then paralyzing nerve conduction, resulting in rapid death. This compound can be used as a reference compound, in the determination of several neonicotinoid insecticides present in bee pollen, using ultra-high performance liquid chromatography (UHPLC) coupled with mass spectrometry (MS).
- Smiles
- ClC1=NC=C(S1)CN2COCN(C([2H])([2H])[2H])/C2=N/[N+]([O-])=O
- InChi Key
- NWWZPOKUUAIXIW-FVFGAQAMSA-N
- References
- (1) A. Schaafsma, et al., PLOSone 10, e0118139 (2015) , (2) S. Valverde, et al., Electrophoresis 37, 2470 (2016) , (3) Y.-F. Huang, et al., Appl. Sci. 10, 6775 (2020)
- InChi
- InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8-/i1D3
Thiamethoxam-d3 is deuterium labelled Thiamethoxam, which is a neonicotinoid insecticide. Neonicotinoids (NNIs) are a family of active substances used in plant protection to control harmful insects and also in veterinary medicine. Neonicotinoids act selectively on the insect nicotinic acetylcholine receptors (nAChRs), initially stimulating postsynaptic receptors, increasing Na+ ingress and K+ egress and then paralyzing nerve conduction, resulting in rapid death. This compound can be used as a reference compound, in the determination of several neonicotinoid insecticides present in bee pollen, using ultra-high performance liquid chromatography (UHPLC) coupled with mass spectrometry (MS).
Additional information
| Synonyms | 3-(2-Chloro-5-thiazolylmethyl)tetrahydro-5-methyl-d3-N-nitro-4H-1,3,5-oxadiazin-4-imine |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white powder |
| CAS-Number | 1294048-82-0 |
| Molecular Formula | C8D3H7ClN5O3S |
| Molecular Weight | 294.73 |
| Identity | 1H-NMR |
| Solvents | DMSO, chloroform |
| Smiles | ClC1=NC=C(S1)CN2COCN(C([2H])([2H])[2H])/C2=N/[N+]([O-])=O |
| InChi Key | NWWZPOKUUAIXIW-FVFGAQAMSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H228,H302,H361fd,H410 |
| Precautionary statements | P202 – P210 – P240 – P273 – P301 + P312 – P308 + P313 |
| GHS Symbol | GHS02+GHS07+08+09 |
| Signal word | Danger |
| RIDADR | UN1325 |
| Transportation | Packing Group II |
| References | (1) A. Schaafsma, et al., PLOSone 10, e0118139 (2015), (2) S. Valverde, et al., Electrophoresis 37, 2470 (2016), (3) Y.-F. Huang, et al., Appl. Sci. 10, 6775 (2020) |
| InChi | InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8-/i1D3 |
| Quantity | 25 mg, Bulk |
