Specifications
- Purity
- ≥99% (HPLC)
- Identity
- 1H-NMR
- Appearance
- Off-white powder
Properties
- Density
- 1.154 g/cm3
- Melting Point
- 223 - 225 °C
- Solvents
- ethanol, methanol, water (slightly)
Downloads
- Safety Data Sheet
- CDX T0153 MSDS.pdf
Available from stock
Tirofiban
- SKU
- T0153
Category: API's & Intermediates
- Synonyms
- MK-383 , L-700,462 , (2S)-2-(Butylsulfonylamino)-3-{4-[4-(4-piperidyl)butoxy}phenyl propanoic acid , N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine
- 144494-65-5
- CAS-Number
- C22H36N2O5S
- Molecular Formula
- 440.6
- Molecular Weight
- Long Term Storage
- -20°C
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Handling Advice
- Protect from light and moisture.
- Short Term Storage
- +4°C
- Shipping
- AMBIENT
- Transportation
- Not dangerous goods
- Signal word
- Warning
- GHS Symbol
- GHS07
- Precautionary statements
- P261-P305 + P351 + P338
- Hazard statements
- H315-H319-H335
- Description
- Synthetic non-peptide selective glycoprotein (GP) IIb/IIIa receptor antagonist/inhibitor. Anticoagulant, specifically, an anti-platelet aggregation inhibitor.
- InChi
- InChI=1S/C22H36N2O5S/c1-2-3-16-30(27,28)24-21(22(25)26)17-19-7-9-20(10-8-19)29-15-5-4-6-18-11-13-23-14-12-18/h7-10,18,21,23-24H,2-6,11-17H2,1H3,(H,25,26)/t21-/m0/s1
- References
- (1) G.D. Hartman, et al.: J. Med. Chem. 35, 4640 (1992) , (2) K. Peerlinck, et al.: Cirulation 88, 1512 (1993) , (3) M.S. Egbertson, et al.: J. Med. Chem. 37, 2537 (1994) , (4) J.S. Barret, et al.: Clin. Pharmacol. Ther. 56, 377 (1994) , (5) J.J. Lynch, et al.: J. Pharmacol. Exp. Ther. 272, 20 (1995) , (6) B.S. Coller, et al.: J. Clin. Invest. 100, S57 (1997)
- InChi Key
- COKMIXFXJJXBQG-NRFANRHFSA-N
- Smiles
- OC([C@@H](NS(=O)(CCCC)=O)CC1=CC=C(OCCCCC2CCNCC2)C=C1)=O
Synthetic non-peptide selective glycoprotein (GP) IIb/IIIa receptor antagonist/inhibitor. Anticoagulant, specifically, an anti-platelet aggregation inhibitor.
Additional information
| Synonyms | MK-383, L-700,462, (2S)-2-(Butylsulfonylamino)-3-{4-[4-(4-piperidyl)butoxy}phenyl propanoic acid, N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine |
|---|---|
| Purity | ≥99% (HPLC) |
| Appearance | Off-white powder |
| CAS-Number | 144494-65-5 |
| Molecular Formula | C22H36N2O5S |
| Molecular Weight | 440.6 |
| Identity | 1H-NMR |
| Solvents | ethanol, methanol, water (slightly) |
| Melting Point | 223 – 225 °C |
| Density | 1.154 g/cm3 |
| Smiles | OC([C@@H](NS(=O)(CCCC)=O)CC1=CC=C(OCCCCC2CCNCC2)C=C1)=O |
| InChi Key | COKMIXFXJJXBQG-NRFANRHFSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305 + P351 + P338 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) G.D. Hartman, et al.: J. Med. Chem. 35, 4640 (1992), (2) K. Peerlinck, et al.: Cirulation 88, 1512 (1993), (3) M.S. Egbertson, et al.: J. Med. Chem. 37, 2537 (1994), (4) J.S. Barret, et al.: Clin. Pharmacol. Ther. 56, 377 (1994), (5) J.J. Lynch, et al.: J. Pharmacol. Exp. Ther. 272, 20 (1995), (6) B.S. Coller, et al.: J. Clin. Invest. 100, S57 (1997) |
| InChi | InChI=1S/C22H36N2O5S/c1-2-3-16-30(27,28)24-21(22(25)26)17-19-7-9-20(10-8-19)29-15-5-4-6-18-11-13-23-14-12-18/h7-10,18,21,23-24H,2-6,11-17H2,1H3,(H,25,26)/t21-/m0/s1 |
| Quantity | 5 mg, 25 mg, 100 mg, Bulk |
