Available from stock

Tirofiban

SKU: T0153

Category: API's & Intermediates

Synonyms: MK-383 , L-700,462 , (2S)-2-(Butylsulfonylamino)-3-{4-[4-(4-piperidyl)butoxy}phenyl propanoic acid , N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine; 144494-65-5
CAS-Number: C₂₂H₃₆N₂O₅S
Molecular Formula: 440.6
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥99% (HPLC)
Appearance: Off-white powder
Identity: 1H-NMR

Properties

Solvents: ethanol, methanol, water (slightly)
Melting Point: 223 - 225 °C
Density: 1.154 g/cm3

Documentation

Safety Data Sheet (SDS): CDX T0153 MSDS.pdf

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: -20°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.

Hazard statements: H315-H319-H335
Precautionary statements: P261-P305 + P351 + P338
GHS Symbol: GHS07
Signal word: Warning
Transportation: Not dangerous goods

Description: Synthetic non-peptide selective glycoprotein (GP) IIb/IIIa receptor antagonist/inhibitor. Anticoagulant, specifically, an anti-platelet aggregation inhibitor.
Smiles: OC([C@@H](NS(=O)(CCCC)=O)CC1=CC=C(OCCCCC2CCNCC2)C=C1)=O
InChi Key: COKMIXFXJJXBQG-NRFANRHFSA-N
References: (1) G.D. Hartman, et al.: J. Med. Chem. 35, 4640 (1992) , (2) K. Peerlinck, et al.: Cirulation 88, 1512 (1993) , (3) M.S. Egbertson, et al.: J. Med. Chem. 37, 2537 (1994) , (4) J.S. Barret, et al.: Clin. Pharmacol. Ther. 56, 377 (1994) , (5) J.J. Lynch, et al.: J. Pharmacol. Exp. Ther. 272, 20 (1995) , (6) B.S. Coller, et al.: J. Clin. Invest. 100, S57 (1997)
InChi: InChI=1S/C22H36N2O5S/c1-2-3-16-30(27,28)24-21(22(25)26)17-19-7-9-20(10-8-19)29-15-5-4-6-18-11-13-23-14-12-18/h7-10,18,21,23-24H,2-6,11-17H2,1H3,(H,25,26)/t21-/m0/s1

Synthetic non-peptide selective glycoprotein (GP) IIb/IIIa receptor antagonist/inhibitor. Anticoagulant, specifically, an anti-platelet aggregation inhibitor.

SKU: T0153 Category: API's & Intermediates

Additional information

Additional information

Synonyms	MK-383, L-700,462, (2S)-2-(Butylsulfonylamino)-3-{4-[4-(4-piperidyl)butoxy}phenyl propanoic acid, N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine
Purity	≥99% (HPLC)
Appearance	Off-white powder
CAS-Number	144494-65-5
Molecular Formula	C22H36N2O5S
Molecular Weight	440.6
Identity	1H-NMR
Solvents	ethanol, methanol, water (slightly)
Melting Point	223 – 225 °C
Density	1.154 g/cm3
Smiles	OC([C@@H](NS(=O)(CCCC)=O)CC1=CC=C(OCCCCC2CCNCC2)C=C1)=O
InChi Key	COKMIXFXJJXBQG-NRFANRHFSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Hazard statements	H315-H319-H335
Precautionary statements	P261-P305 + P351 + P338
GHS Symbol	GHS07
Signal word	Warning
Transportation	Not dangerous goods
References	(1) G.D. Hartman, et al.: J. Med. Chem. 35, 4640 (1992), (2) K. Peerlinck, et al.: Cirulation 88, 1512 (1993), (3) M.S. Egbertson, et al.: J. Med. Chem. 37, 2537 (1994), (4) J.S. Barret, et al.: Clin. Pharmacol. Ther. 56, 377 (1994), (5) J.J. Lynch, et al.: J. Pharmacol. Exp. Ther. 272, 20 (1995), (6) B.S. Coller, et al.: J. Clin. Invest. 100, S57 (1997)
InChi	InChI=1S/C22H36N2O5S/c1-2-3-16-30(27,28)24-21(22(25)26)17-19-7-9-20(10-8-19)29-15-5-4-6-18-11-13-23-14-12-18/h7-10,18,21,23-24H,2-6,11-17H2,1H3,(H,25,26)/t21-/m0/s1
Quantity	5 mg, 25 mg, 100 mg, Bulk