Specifications
- Purity
- ≥98% (TLC)
- Appearance
- White to off-white powder
- Identity
- 1H-NMR
Properties
- Solvents
- water (10 mg/ml)
- Melting Point
- 288-290 °C (dec.)(lit.)
Available from stock
Yohimbine hydrochloride
- SKU
- Y0013
Category: API's & Intermediates
- Synonyms
- 17-Hydroxyyohimban-16-carboxylic acid methyl ester hydrochloride , Actibine , Antagonil , Aphrodyne , Dayto-Himbin , Erex , NIH 9689 , NSC19509 , Thybine
- 65-19-0
- CAS-Number
- C21H26N2O3 · HCl
- Molecular Formula
- 390.90
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Hazard statements
- H300-H311-H331
- Precautionary statements
- P261-P264-P280-P301 + P310-P311
- GHS Symbol
- GHS06
- Signal word
- Danger
- RIDADR
- 1544PSN2 6.1
- Transportation
- Packing Group II
- Description
- ?2-adrenoceptor antagonist. pKi values are 8.52, 8.00 and 9.17 for human ?2A, ?2B and ?2C receptors, respectively.
- Smiles
- O[C@@H]1[C@H](C(OC)=O)[C@](C2)([H])[C@](CC1)([H])CN(CC3)[C@]2([H])C4=C3C(C=CC=C5)=C5N4.Cl
- InChi Key
- PIPZGJSEDRMUAW-VJDCAHTMSA-N
- References
- (1) M.R. Goldberg & D. Robertson , Pharmacol. Rev. 35, 143 (1983) , (2) W.S. Redfern & A. Williams , Br. J. Pharmacol. 116, 2081 (1995) , (3) S.G. Lalchandani, et al. , JPET 303, 979 (2002) , (4) P. Lahiri, et al. , Platelets 16, 111 (2005)
- InChi
- InChI=1S/C21H26N2O3.ClH/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24 , /h2-5,12,15,17-19,22,24H,6-11H2,1H3 , 1H/t12-,15-,17-,18-,19+ , /m0./s1
?2-adrenoceptor antagonist. pKi values are 8.52, 8.00 and 9.17 for human ?2A, ?2B and ?2C receptors, respectively.
Additional information
| Synonyms | 17-Hydroxyyohimban-16-carboxylic acid methyl ester hydrochloride, Actibine, Antagonil, Aphrodyne, Dayto-Himbin, Erex, NIH 9689, NSC19509, Thybine |
|---|---|
| Purity | ≥98% (TLC) |
| Appearance | White to off-white powder |
| CAS-Number | 65-19-0 |
| Molecular Formula | C21H26N2O3 · HCl |
| Molecular Weight | 390.90 |
| Identity | 1H-NMR |
| Solvents | water (10 mg/ml) |
| Melting Point | 288-290 °C (dec.)(lit.) |
| Smiles | O[C@@H]1[C@H](C(OC)=O)[C@](C2)([H])[C@](CC1)([H])CN(CC3)[C@]2([H])C4=C3C(C=CC=C5)=C5N4.Cl |
| InChi Key | PIPZGJSEDRMUAW-VJDCAHTMSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H300-H311-H331 |
| Precautionary statements | P261-P264-P280-P301 + P310-P311 |
| GHS Symbol | GHS06 |
| Signal word | Danger |
| RIDADR | 1544PSN2 6.1 |
| Transportation | Packing Group II |
| References | (1) M.R. Goldberg & D. Robertson, Pharmacol. Rev. 35, 143 (1983), (2) W.S. Redfern & A. Williams, Br. J. Pharmacol. 116, 2081 (1995), (3) S.G. Lalchandani, et al., JPET 303, 979 (2002), (4) P. Lahiri, et al., Platelets 16, 111 (2005) |
| InChi | InChI=1S/C21H26N2O3.ClH/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24, /h2-5,12,15,17-19,22,24H,6-11H2,1H3, 1H/t12-,15-,17-,18-,19+, /m0./s1 |
| Quantity | 5 g, 25 g, Bulk |
