Available from stock

Zilpaterol hydrochloride

SKU: Z0025

Category: API's & Intermediates

Synonyms: (6RS,7RS)-4,5,6, 7-Tetrahydro-7-hydroxy-6-[(1-methylethyl)amino]imidazo[ 4,5,1-jk][1]benzazepin-2(1H)-one hydrochloride; 119520-06-8
CAS-Number: C₁₄H₁₉N₃O₂ · HCl
Molecular Formula: 297.78
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥97% (HPLC)
Appearance: White to off-white powder
Identity: 1H-NMR

Properties

Solvents: water, methanol (slightly)
Melting Point: 230°C

Documentation

Safety Data Sheet (SDS): CDX Z0025 MSDS_1.2.pdf

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: -20°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.

Transportation: Not dangerous goods

Description: Synthetic &beta,2-adrenoreceptor agonist that binds with the muscle &beta,-adrenoreceptors, leading to the activation of protein kinase A, an enzyme responsible for changes in protein synthesis and degradation, in particular in skeletal muscles. Due to its partial activity towards &beta,1-adrenoreceptors, has also the potential to affect cardiac muscle. In consequence, application of zilpaterol leads to preferential induction of fast glycolytic fibre types over slow oxidative fibre types resulting in enhanced growth efficiency and carcass leanness. Used as a veterinary drug in cattle to enhance growth performance in several countries.
Smiles: O=C1NC2=C(N1CCC(NC(C)C)C3O)C3=CC=C2.[H]Cl
InChi Key: GIEFXLLRTJNFGT-UHFFFAOYSA-N
References: B. Bocca, et al., J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 783, 141 (2003) , C.P. Birkelo, Vet. Clin. North Am. Food Anim. Pract. 19, 599 (2003) (Review) , K.C. Verhoeckx, et al., J. Vet. Pharmacol. Ther. 28, 531 (2005) , J.L. Montgomery, et al., J. Anim. Sci. 87, 1374 (2009) , J.M. Leheska, et al., J. Anim. Sci. 87, 1384 (2009) , C. Kern, et al., J. Med. Chem. 52, 1773 (2009) , T.J. Centner, et al., J. Anim. Sci. 92, 4234 (2014) (Review) , C.L. Van Bibber-Krueger, et al., J. Anim. Sci. 93, 2419 (2015)
InChi: InChI=1S/C14H19N3O2.ClH/c1-8(2)15-11-6-7-17-12-9(13(11)18)4-3-5-10(12)16-14(17)19,/h3-5,8,11,13,15,18H,6-7H2,1-2H3,(H,16,19),1H

Synthetic &beta,2-adrenoreceptor agonist that binds with the muscle &beta,-adrenoreceptors, leading to the activation of protein kinase A, an enzyme responsible for changes in protein synthesis and degradation, in particular in skeletal muscles. Due to its partial activity towards &beta,1-adrenoreceptors, has also the potential to affect cardiac muscle. In consequence, application of zilpaterol leads to preferential induction of fast glycolytic fibre types over slow oxidative fibre types resulting in enhanced growth efficiency and carcass leanness. Used as a veterinary drug in cattle to enhance growth performance in several countries.

SKU: Z0025 Category: API's & Intermediates

Additional information

Additional information

Synonyms	(6RS,7RS)-4,5,6, 7-Tetrahydro-7-hydroxy-6-[(1-methylethyl)amino]imidazo[ 4,5,1-jk][1]benzazepin-2(1H)-one hydrochloride
Purity	≥97% (HPLC)
Appearance	White to off-white powder
CAS-Number	119520-06-8
Molecular Formula	C14H19N3O2 · HCl
Molecular Weight	297.78
Identity	1H-NMR
Solvents	water, methanol (slightly)
Melting Point	230°C
Smiles	O=C1NC2=C(N1CCC(NC(C)C)C3O)C3=CC=C2.[H]Cl
InChi Key	GIEFXLLRTJNFGT-UHFFFAOYSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Transportation	Not dangerous goods
References	B. Bocca, et al., J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 783, 141 (2003), C.P. Birkelo, Vet. Clin. North Am. Food Anim. Pract. 19, 599 (2003) (Review), K.C. Verhoeckx, et al., J. Vet. Pharmacol. Ther. 28, 531 (2005), J.L. Montgomery, et al., J. Anim. Sci. 87, 1374 (2009), J.M. Leheska, et al., J. Anim. Sci. 87, 1384 (2009), C. Kern, et al., J. Med. Chem. 52, 1773 (2009), T.J. Centner, et al., J. Anim. Sci. 92, 4234 (2014) (Review), C.L. Van Bibber-Krueger, et al., J. Anim. Sci. 93, 2419 (2015)
InChi	InChI=1S/C14H19N3O2.ClH/c1-8(2)15-11-6-7-17-12-9(13(11)18)4-3-5-10(12)16-14(17)19,/h3-5,8,11,13,15,18H,6-7H2,1-2H3,(H,16,19),1H
Quantity	5 mg, 10 mg, Bulk