(-)-Epigallocatechin
- SKU
- E0182
Category: Phytochemicals
- Synonyms
- (?)-EGC , epi-Gallocatechin , NSC 674039 , (-)-cis-3,3',4',5,5',7-Hexahydroxyflavane , CCRIS 5441
- 970-74-1
- CAS-Number
- C15H14O7
- Molecular Formula
- 306.27
- Molecular Weight
Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- White to beige to pink powder
- Identity
- 1H-NMR
Properties
- Solvents
- PBS (1 mg/ml), ethanol (5 mg/ml), DMSO (15 mg/ml), DMF (20 mg/ml)
- Melting Point
- 220°C
- UV / Vis
- 228 nm (in MeOH)
- Optical Activity
- -50° (c=0.04, EtOH), -58.2° (20°C, methanol)
- Shipping
- AMBIENT
- Short Term Storage
- RT
- Long Term Storage
- +4°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at +4°C.
- Transportation
- Not dangerous goods
- Description
- (-)-Epigallocatechin ((-)-EGC) is a major green tea polyphenol with antioxidant, anti-inflammatory and anticancer activities. It has been shown to scavenge DPPH radicals and to prevent the growth of several different AML cell lines at micromolar concentrations.
- Smiles
- O[C@H]1[C@@H](C2=CC(O)=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C3C1
- InChi Key
- XMOCLSLCDHWDHP-IUODEOHRSA-N
- References
- (1) J.Z. Xu, et al., Br, J, Nutr. 91, 873 (2004) , (2) Y. Kushima, et al., Biol. Pharm. Bull. 32, 899 (2009) , (3) Y. Kadome & S. Fujisawa, Molecules 16, 10457 (2011) , (4) B.T.K. Ly, et al., PLoS One 8, 1 (2013)
- InChi
- InChI=1S/C15H14O7/c16-7-3-9(17)8-5-12(20)15(22-13(8)4-7)6-1-10(18)14(21)11(19)2-6/h1-4,12,15-21H,5H2/t12-,15-/m1/s1
(-)-Epigallocatechin ((-)-EGC) is a major green tea polyphenol with antioxidant, anti-inflammatory and anticancer activities. It has been shown to scavenge DPPH radicals and to prevent the growth of several different AML cell lines at micromolar concentrations.