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    N-Butanoyl-L-homoserine lactone

    Available from stock

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      N-Butanoyl-L-homoserine lactone

      SKU
      B0267

      Category: Quorum Sensing

      Synonyms
      C4-HSL , N-(2-Oxotetrahydro-3-furanyl)butanamide
      67605-85-0
      CAS-Number
      C8H13NO3
      Molecular Formula
      171.2
      Molecular Weight

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥97% (GC)
      Identity
      1H-NMR
      Appearance
      White solid

      Properties

      Solvents
      water (10 mg/ml at 25°C), ethanol, DMSO (~30 mg/ml), DMF (~30 mg/ml)

      Downloads

      Safety Data Sheet
      CDX B0267 MSDS.pdf
      Short Term Storage
      +4°C
      Use / Stability
      Stable for at least 2 years after receipt when stored at -20°C.
      Handling Advice
      Protect from light and moisture.
      Long Term Storage
      -20°C
      Shipping
      AMBIENT
      Transportation
      Not dangerous goods
      Description
      N-butyryl-L-Homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.
      InChi
      InChI=1S/C8H13NO3/c1-2-3-7(10)9-6-4-5-12-8(6)11/h6H,2-5H2,1H3,(H,9,10)
      References
      (1) T.A. Gould, et al.: J. Bacteriol. 188, 773 (2006) , (2) S.P. Diggle, et al.: J. Bacteriol. 184, 2576 (2002) , (3) G. Pessi, et al.: J. Bacteriol. 183, 6676 (2001) , (4) T.T. Hoang & H.P.Schweizer: J. Bacteriol. 181, 5489 (1999) , (5) T. Morohoshi, et al.: J. Biosci. Bioeng. 98, 274 (2004) , (6) Z.-Q. Luo, et al.: J. Bacteriol. 186, 5665 (2003) , (7) J.M. Henke & B.L. Bassler: Trends Cell Biol. 14, 648 (2004)
      InChi Key
      VFFNZZXXTGXBOG-UHFFFAOYSA-N
      Smiles
      CCCC(=O)N[C@H]1CCOC1=O

      N-butyryl-L-Homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.

      SKU: B0267 Category: Quorum Sensing
      • Additional information

      Additional information

      Synonyms

      C4-HSL, N-(2-Oxotetrahydro-3-furanyl)butanamide

      Purity

      ≥97% (GC)

      Appearance

      White solid

      CAS-Number

      67605-85-0

      Molecular Formula

      C8H13NO3

      Molecular Weight

      171.2

      Identity

      1H-NMR

      Solvents

      water (10 mg/ml at 25°C), ethanol, DMSO (~30 mg/ml), DMF (~30 mg/ml)

      Smiles

      CCCC(=O)N[C@H]1CCOC1=O

      InChi Key

      VFFNZZXXTGXBOG-UHFFFAOYSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      -20°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at -20°C.

      Transportation

      Not dangerous goods

      References

      (1) T.A. Gould, et al.: J. Bacteriol. 188, 773 (2006), (2) S.P. Diggle, et al.: J. Bacteriol. 184, 2576 (2002), (3) G. Pessi, et al.: J. Bacteriol. 183, 6676 (2001), (4) T.T. Hoang & H.P.Schweizer: J. Bacteriol. 181, 5489 (1999), (5) T. Morohoshi, et al.: J. Biosci. Bioeng. 98, 274 (2004), (6) Z.-Q. Luo, et al.: J. Bacteriol. 186, 5665 (2003), (7) J.M. Henke & B.L. Bassler: Trends Cell Biol. 14, 648 (2004)

      InChi

      InChI=1S/C8H13NO3/c1-2-3-7(10)9-6-4-5-12-8(6)11/h6H,2-5H2,1H3,(H,9,10)

      Quantity

      10 mg, 50 mg, Bulk

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