N-Butanoyl-L-homoserine lactone

SKU: B0267

Category: Quorum Sensing

Synonyms: C4-HSL , N-(2-Oxotetrahydro-3-furanyl)butanamide; 67605-85-0
CAS-Number: C₈H₁₃NO₃
Molecular Formula: 171.2
Molecular Weight

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥97% (GC)
Identity: 1H-NMR
Appearance: White solid

Properties

Solvents: water (10 mg/ml at 25°C), ethanol, DMSO (~30 mg/ml), DMF (~30 mg/ml)

Short Term Storage: +4°C
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.
Handling Advice: Protect from light and moisture.
Long Term Storage: -20°C
Shipping: AMBIENT

Transportation: Not dangerous goods

Description: N-butyryl-L-Homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.
InChi: InChI=1S/C8H13NO3/c1-2-3-7(10)9-6-4-5-12-8(6)11/h6H,2-5H2,1H3,(H,9,10)
References: (1) T.A. Gould, et al.: J. Bacteriol. 188, 773 (2006) , (2) S.P. Diggle, et al.: J. Bacteriol. 184, 2576 (2002) , (3) G. Pessi, et al.: J. Bacteriol. 183, 6676 (2001) , (4) T.T. Hoang & H.P.Schweizer: J. Bacteriol. 181, 5489 (1999) , (5) T. Morohoshi, et al.: J. Biosci. Bioeng. 98, 274 (2004) , (6) Z.-Q. Luo, et al.: J. Bacteriol. 186, 5665 (2003) , (7) J.M. Henke & B.L. Bassler: Trends Cell Biol. 14, 648 (2004)
InChi Key: VFFNZZXXTGXBOG-UHFFFAOYSA-N
Smiles: CCCC(=O)N[C@H]1CCOC1=O

N-butyryl-L-Homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of this kind of molecule include regulation of virulence in general, infection prevention, and formation of biofilms.

SKU: B0267 Category: Quorum Sensing

Additional information

Additional information

Synonyms	C4-HSL, N-(2-Oxotetrahydro-3-furanyl)butanamide
Purity	≥97% (GC)
Appearance	White solid
CAS-Number	67605-85-0
Molecular Formula	C8H13NO3
Molecular Weight	171.2
Identity	1H-NMR
Solvents	water (10 mg/ml at 25°C), ethanol, DMSO (~30 mg/ml), DMF (~30 mg/ml)
Smiles	CCCC(=O)N[C@H]1CCOC1=O
InChi Key	VFFNZZXXTGXBOG-UHFFFAOYSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Transportation	Not dangerous goods
References	(1) T.A. Gould, et al.: J. Bacteriol. 188, 773 (2006), (2) S.P. Diggle, et al.: J. Bacteriol. 184, 2576 (2002), (3) G. Pessi, et al.: J. Bacteriol. 183, 6676 (2001), (4) T.T. Hoang & H.P.Schweizer: J. Bacteriol. 181, 5489 (1999), (5) T. Morohoshi, et al.: J. Biosci. Bioeng. 98, 274 (2004), (6) Z.-Q. Luo, et al.: J. Bacteriol. 186, 5665 (2003), (7) J.M. Henke & B.L. Bassler: Trends Cell Biol. 14, 648 (2004)
InChi	InChI=1S/C8H13NO3/c1-2-3-7(10)9-6-4-5-12-8(6)11/h6H,2-5H2,1H3,(H,9,10)
Quantity	10 mg, 50 mg, Bulk