Specifications
- Purity
- ≥98% (HPLC)
- Appearance
- Light yellow powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO (20 mg/ml)
Category: Building Blocks, Intermediates, Reagents
6-Chloropurine is a building block in chemical synthesis and is used as an intermediate in the preparation of 9-alkylpurines via alkylation with various substituted alkyl halides in DMSO. 6-Chloropurine based compounds have been shown to display antiviral and antitumor properties.
Synonyms | 6-Chloro-9H-purine |
---|---|
Purity | ≥98% (HPLC) |
Appearance | Light yellow powder |
CAS-Number | 87-42-3 |
Molecular Formula | C5H3ClN4 |
Molecular Weight | 154.56 |
Identity | 1H-NMR |
Solvents | DMSO (20 mg/ml) |
Smiles | ClC1=C2C(NC=N2)=NC=N1 |
InChi Key | ZKBQDFAWXLTYKS-UHFFFAOYSA-N |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | +4°C |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
Hazard statements | H302 |
GHS Symbol | GHS07 |
Signal word | Warning |
Transportation | Not dangerous goods |
References | (1) A.C. Sartorelli, et al., J. Pharmacol. Exp. Ther. 134, 123 (1961), (2) J.A. Montgomery & C. Temple, JACS 83, 630 (1961), (3) M. Fuertes, et al., Tetrahedron 26, 4823 (1970), (4) I.Y. Hwang, et al., J. Pharmacol. Exp. Ther. 264, 41 (1993), (5) E. Kierzek & R. Kierzek, Curr. Protoc. Nucleic Acid Chem. Chapter 4, Unit 4.23 (2004), (6) P. Plackova, et al., J. Enzyme Inhib. Med. Chem. 30, 57 (2015), (7) S. Schwarz, et al., Eur. J. Med. Chem. 90, 595 (2015) |
InChi | InChI=1S/C5H3ClN4/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H,7,8,9,10) |
Quantity | 5 g, 25 g, Bulk |