Specifications
- Purity
- ≥95% (HPLC)
- Appearance
- White to off-white solid
- Identity
- 1H-NMR
Properties
- Solvents
- water
- Melting Point
- 230 °C( lit.)
- Optical Activity
- [α]/D 64.0±3.0°, c = 1 in H2O
Category: Carbohydrates
D-chiro Inositol is a insulin sensitizing agent. It is a secondary messenger in the signal transduction of insulin. D-chiro Inositol reduces the effects of polycystic ovary syndrome (PCOS) activity in cells. D-chiro Inositol is a mediator of insulin action via accelerating the dephosphorylation of glycogen synthase and pyruvate dehydrogenase and rate limiting enzymes of non-oxidative and oxidative glucose disposal. As a result of these actions D-chiro Inositol functions to reduce insulin resistance and increase sensitivity and glucose disposal. Can also be used as a building block for organic synthesis.
Synonyms | DCI, 1,2,4/3,5,6-Hexahydroxycyclohexane, D-(+)-chiro-Inositol |
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Purity | ≥95% (HPLC) |
Appearance | White to off-white solid |
CAS-Number | 643-12-9 |
Molecular Formula | C6H12O6 |
Molecular Weight | 180.16 |
Identity | 1H-NMR |
Solvents | water |
Melting Point | 230 °C( lit.) |
Optical Activity | [α]/D 64.0±3.0°, c = 1 in H2O |
Smiles | O[C@H]1[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O |
InChi Key | CDAISMWEOUEBRE-LKPKBOIGSA-N |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | +4°C |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
Transportation | Not dangerous goods |
References | (1) J. Larner, IUBMB Life 51, 139 (2001) (Review), (2) J. Larner, Int. J. Exp. Diabetes Res. 3 47 (2002), (3) J. Larner, et al., Mol. Med. 16, 543 (2010) (Review), (4) N. Galazis, et al., Gynecol. Endocrinol. 27, 256 (2011) (Review), (5) G.G. Adams, et al., Crit. Rev. Food. Sci. Nutr. 54, 1322 (2014) (Review) |
InChi | InChI=1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H/t1-,2-,3-,4-,5+,6+/m0/s1 |
Quantity | 100 mg, 1 g, Bulk |