Specifications
- Purity
- ≥98% (HPLC)
- Identity
- 1H-NMR
- Appearance
- White to off-white powder
Properties
- Melting Point
- 240-244 °C (lit.)
- Solvents
- ethanol
Available from stock
3-Chloro-4-methyl-7-hydroxycoumarin
- SKU
- C0351
Category: Building Blocks, Intermediates, Reagents
- Synonyms
- Chlorferon , 3-Chloro-4-methylumbelliferone , 3-chloro-7-hydroxy-4-methylcoumarin , CHMC , Chlorferone , NSC 24924 , NSC 44204
- 6174-86-3
- CAS-Number
- C10H7ClO3
- Molecular Formula
- 210.61
- Molecular Weight
- Hazard statements
- H315-H319-H335
- Transportation
- Not dangerous goods
- Signal word
- Warning
- GHS Symbol
- GHS07
- Precautionary statements
- P261-P305 + P351 + P338
- Description
- Major metabolite and hydrolysis product of coumaphos, an organophosphate pesticide. Shown to have acetylcholinesterase and butyrylcholinesterase inhibitor activity and moderate to weak &alpha,-glucosidase inhibitory and antioxidant scavenging activity. Also used as a building block in the synthesis of fluorogenic substrates for the detection of bacterial &beta,-Galactosidase.
- InChi
- InChI=1S/C10H7ClO3/c1-5-7-3-2-6(12)4-8(7)14-10(13)9(5)11/h2-4,12H,1H3
- References
- V. Simeon-Rudolf, et al., Chem. Biol. Interact. 119-120, 119 (1999) , T. Jindal, et al., J. Environ. Sci. Health B. 35, 309 (2000) , K.F. Chilvers, et al., J. Appl. Microbiol. 91, 1118 (2001) , J. Ha, et al., Bioresour. Technol. 100, 1138 (2009) , B.C. Raju, et al., Bioorg. Med. Chem. 18, 358 (2010)
- InChi Key
- ODZHLDRQCZXQFQ-UHFFFAOYSA-N
- Smiles
- O=C1OC2=C(C=CC(O)=C2)C(C)=C1Cl
Major metabolite and hydrolysis product of coumaphos, an organophosphate pesticide. Shown to have acetylcholinesterase and butyrylcholinesterase inhibitor activity and moderate to weak &alpha,-glucosidase inhibitory and antioxidant scavenging activity. Also used as a building block in the synthesis of fluorogenic substrates for the detection of bacterial &beta,-Galactosidase.
Additional information
| Synonyms | Chlorferon, 3-Chloro-4-methylumbelliferone, 3-chloro-7-hydroxy-4-methylcoumarin, CHMC, Chlorferone, NSC 24924, NSC 44204 |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white powder |
| CAS-Number | 6174-86-3 |
| Molecular Formula | C10H7ClO3 |
| Molecular Weight | 210.61 |
| Identity | 1H-NMR |
| Solvents | ethanol |
| Melting Point | 240-244 °C (lit.) |
| Smiles | O=C1OC2=C(C=CC(O)=C2)C(C)=C1Cl |
| InChi Key | ODZHLDRQCZXQFQ-UHFFFAOYSA-N |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305 + P351 + P338 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | V. Simeon-Rudolf, et al., Chem. Biol. Interact. 119-120, 119 (1999), T. Jindal, et al., J. Environ. Sci. Health B. 35, 309 (2000), K.F. Chilvers, et al., J. Appl. Microbiol. 91, 1118 (2001), J. Ha, et al., Bioresour. Technol. 100, 1138 (2009), B.C. Raju, et al., Bioorg. Med. Chem. 18, 358 (2010) |
| InChi | InChI=1S/C10H7ClO3/c1-5-7-3-2-6(12)4-8(7)14-10(13)9(5)11/h2-4,12H,1H3 |
| Quantity | 1 g, 5 g, Bulk |
