Specifications
- Purity
- ≥97% (HPLC)
- Appearance
- White powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO
- Melting Point
- 299 °C (lit.)
Documentation
- Safety Data Sheet (SDS)
- CDX H0052 SDS.pdf
Available from stock
5-Hydroxynicotinic acid
- SKU
- H0052
Category: Building Blocks, Intermediates, Reagents
- Synonyms
- 5-Hydroxypyridine-3-carboxylic acid
- 27828-71-3
- CAS-Number
- C6H5NO3
- Molecular Formula
- 139.11
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- RT
- Long Term Storage
- RT
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at RT.
- Hazard statements
- H315, H319, H335
- Precautionary statements
- P261, P264, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P312, P321, P332 + P313, P337 + P313, P362, P403 + P233, P405, P501
- GHS Symbol
- GHS07
- Signal word
- Warning
- Transportation
- Not dangerous goods
- Description
- A nicotinic acid analog. Substrate analog MHPCO, used in the investigation of the hydroxylation mechanism of the flaovoprotein 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase (MHPCO). Also used as building block for synthesis. Hydroxynicotinic acid is formed by the enzymatic action of nicotinate with nicotinic acid hydroxylase or nicotinate hydroxylase.
- Smiles
- OC1=CN=CC(C(O)=O)=C1
- InChi Key
- ATTDCVLRGFEHEO-UHFFFAOYSA-N
- References
- (1) P. Chaiyen, et al.: Biochem. 43, 3933 (2004) , (2) P. Chaiyen, et al.: Biochemistry 36, 2612 (1997) , (3) P. Chaiyen, et al.: Biochemistry 36, 8060 (1997) , (4) P. Chaiyen, et al.: Biochemistry 36, 13856 (1997)
- InChi
- InChI=1S/C6H5NO3/c8-5-1-4(6(9)10)2-7-3-5/h1-3,8H,(H,9,10)
A nicotinic acid analog. Substrate analog MHPCO, used in the investigation of the hydroxylation mechanism of the flaovoprotein 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase (MHPCO). Also used as building block for synthesis. Hydroxynicotinic acid is formed by the enzymatic action of nicotinate with nicotinic acid hydroxylase or nicotinate hydroxylase.
Additional information
| Synonyms | 5-Hydroxypyridine-3-carboxylic acid |
|---|---|
| Purity | ≥97% (HPLC) |
| Appearance | White powder |
| CAS-Number | 27828-71-3 |
| Molecular Formula | C6H5NO3 |
| Molecular Weight | 139.11 |
| Identity | 1H-NMR |
| Solvents | DMSO |
| Melting Point | 299 °C (lit.) |
| Smiles | OC1=CN=CC(C(O)=O)=C1 |
| InChi Key | ATTDCVLRGFEHEO-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | RT |
| Long Term Storage | RT |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at RT. |
| Hazard statements | H315, H319, H335 |
| Precautionary statements | P261, P264, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P312, P321, P332 + P313, P337 + P313, P362, P403 + P233, P405, P501 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) P. Chaiyen, et al.: Biochem. 43, 3933 (2004), (2) P. Chaiyen, et al.: Biochemistry 36, 2612 (1997), (3) P. Chaiyen, et al.: Biochemistry 36, 8060 (1997), (4) P. Chaiyen, et al.: Biochemistry 36, 13856 (1997) |
| InChi | InChI=1S/C6H5NO3/c8-5-1-4(6(9)10)2-7-3-5/h1-3,8H,(H,9,10) |
| Quantity | 1 g, 5 g, 25 g, Bulk |
