5(6)-TAMRA
- SKU
- C0038
Categories: Fluorescent Detection, Fluorescent Detection
- Synonyms
- 5(6)-Carboxytetramethylrhodamine , 150347-56-1
- 98181-63-6
- CAS-Number
- C25H22N2O5
- Molecular Formula
- 430.45
- Molecular Weight
Specifications
- Purity
- ≥95% (HPLC)
- Appearance
- Dark red to brown powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO, DMF, methanol, aqueous buffers (pH ≥65)
- Melting Point
- ≥300 °C
- Fluorescence
- λex 543 nm, λem 572 nm in methanol
Documentation
- Safety Data Sheet (SDS)
- CDX C0038 MSDS.pdf
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- +4°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at +4°C.
- Hazard statements
- H302
- GHS Symbol
- GHS07
- Signal word
- Warning
- Transportation
- Not dangerous goods
- For Research Use Only
- Not Intended for Diagnostic or Therapeutic Use.
- Description
- Mixed isomers of carboxytetramethylrhodamine free acid. Tetramethylrhodamine (TMR) is one of the fluorophores most often used for preparing peptide, protein, nucleotide and nucleic acid conjugates. TMR dyes have been widely used as acceptors for FAM fluorophores in a variety of FRET studies. The dye can be coupled to primary or secondary amines via standard peptide chemistry.
- Smiles
- CC(O)=O.CN(C)C1=CC2=C(C=C1)C1(OC(=O)C3=C1C=CC=C3)C1=CC=C(C=C1O2)N(C)C
- InChi Key
- VNRGODVGRCXKSJ-UHFFFAOYSA-N
- References
- (1) N.A. Evans et al.: J. Neurochem. 77, 476 (2001) , (2) K.L. Hess et al.: Cytometry 27, 145 (1997) , (3) W. Lutz et al.: J. Biol. Chem. 267, 1109 (1992)
- InChi
- InChI=1S/C24H22N2O3.C2H4O2/c1-25(2)15-9-11-19-21(13-15)28-22-14-16(26(3)4)10-12-20(22)24(19)18-8-6-5-7-17(18)23(27)29-24
Mixed isomers of carboxytetramethylrhodamine free acid. Tetramethylrhodamine (TMR) is one of the fluorophores most often used for preparing peptide, protein, nucleotide and nucleic acid conjugates. TMR dyes have been widely used as acceptors for FAM fluorophores in a variety of FRET studies. The dye can be coupled to primary or secondary amines via standard peptide chemistry.