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    5(6)-TAMRA

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    5(6)-TAMRA

    SKU
    C0038

    Category: Fluorescent Detection

    Synonyms
    5(6)-Carboxytetramethylrhodamine , 150347-56-1
    98181-63-6
    CAS-Number
    C25H22N2O5
    Molecular Formula
    430.45
    Molecular Weight

    • Product Data
    • Handling
    • Safety Information
    • Details

    Specifications

    Purity
    ≥85% (sum of isomers, HPCE)
    Identity
    1H-NMR
    Appearance
    Dark red to brown powder

    Properties

    Fluorescence
    λex 543 nm, λem 572 nm in methanol
    Melting Point
    ≥300 °C
    Solvents
    DMSO, DMF, methanol, aqueous buffers (pH ≥65)

    Downloads

    Safety Data Sheet
    CDX C0038 MSDS.pdf
    Long Term Storage
    +4°C
    Use / Stability
    Stable for at least 2 years after receipt when stored at +4°C.
    Handling Advice
    Protect from light and moisture.
    Short Term Storage
    +4°C
    Shipping
    AMBIENT
    Transportation
    Not dangerous goods
    Signal word
    Warning
    GHS Symbol
    GHS07
    Hazard statements
    H302
    Description
    Mixed isomers of carboxytetramethylrhodamine free acid. Tetramethylrhodamine (TMR) is one of the fluorophores most often used for preparing peptide, protein, nucleotide and nucleic acid conjugates. TMR dyes have been widely used as acceptors for FAM fluorophores in a variety of FRET studies. The dye can be coupled to primary or secondary amines via standard peptide chemistry.
    InChi
    InChI=1S/C24H22N2O3.C2H4O2/c1-25(2)15-9-11-19-21(13-15)28-22-14-16(26(3)4)10-12-20(22)24(19)18-8-6-5-7-17(18)23(27)29-24
    References
    (1) N.A. Evans et al.: J. Neurochem. 77, 476 (2001) , (2) K.L. Hess et al.: Cytometry 27, 145 (1997) , (3) W. Lutz et al.: J. Biol. Chem. 267, 1109 (1992)
    InChi Key
    VNRGODVGRCXKSJ-UHFFFAOYSA-N
    Smiles
    CC(O)=O.CN(C)C1=CC2=C(C=C1)C1(OC(=O)C3=C1C=CC=C3)C1=CC=C(C=C1O2)N(C)C

    Mixed isomers of carboxytetramethylrhodamine free acid. Tetramethylrhodamine (TMR) is one of the fluorophores most often used for preparing peptide, protein, nucleotide and nucleic acid conjugates. TMR dyes have been widely used as acceptors for FAM fluorophores in a variety of FRET studies. The dye can be coupled to primary or secondary amines via standard peptide chemistry.

    SKU: C0038 Category: Fluorescent Detection
    • Additional information

    Additional information

    Synonyms

    5(6)-Carboxytetramethylrhodamine, 150347-56-1

    Purity

    ≥85% (sum of isomers, HPCE)

    Appearance

    Dark red to brown powder

    CAS-Number

    98181-63-6

    Molecular Formula

    C25H22N2O5

    Molecular Weight

    430.45

    Identity

    1H-NMR

    Solvents

    DMSO, DMF, methanol, aqueous buffers (pH ≥65)

    Melting Point

    ≥300 °C

    Fluorescence

    λex 543 nm, λem 572 nm in methanol

    Smiles

    CC(O)=O.CN(C)C1=CC2=C(C=C1)C1(OC(=O)C3=C1C=CC=C3)C1=CC=C(C=C1O2)N(C)C

    InChi Key

    VNRGODVGRCXKSJ-UHFFFAOYSA-N

    Shipping

    AMBIENT

    Short Term Storage

    +4°C

    Long Term Storage

    +4°C

    Handling Advice

    Protect from light and moisture.

    Use / Stability

    Stable for at least 2 years after receipt when stored at +4°C.

    Hazard statements

    H302

    GHS Symbol

    GHS07

    Signal word

    Warning

    Transportation

    Not dangerous goods

    References

    (1) N.A. Evans et al.: J. Neurochem. 77, 476 (2001), (2) K.L. Hess et al.: Cytometry 27, 145 (1997), (3) W. Lutz et al.: J. Biol. Chem. 267, 1109 (1992)

    InChi

    InChI=1S/C24H22N2O3.C2H4O2/c1-25(2)15-9-11-19-21(13-15)28-22-14-16(26(3)4)10-12-20(22)24(19)18-8-6-5-7-17(18)23(27)29-24

    Quantity

    100 mg, 2 g, Bulk

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