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    5(6)-TAMRA

    Available from stock

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      5(6)-TAMRA

      SKU
      C0038

      Category: Fluorescent Detection

      Synonyms
      5(6)-Carboxytetramethylrhodamine , 150347-56-1
      98181-63-6
      CAS-Number
      C25H22N2O5
      Molecular Formula
      430.45
      Molecular Weight

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥85% (sum of isomers, HPCE)
      Identity
      1H-NMR
      Appearance
      Dark red to brown powder

      Properties

      Fluorescence
      λex 543 nm, λem 572 nm in methanol
      Melting Point
      ≥300 °C
      Solvents
      DMSO, DMF, methanol, aqueous buffers (pH ≥65)

      Downloads

      Safety Data Sheet
      CDX C0038 MSDS.pdf
      Long Term Storage
      +4°C
      Use / Stability
      Stable for at least 2 years after receipt when stored at +4°C.
      Handling Advice
      Protect from light and moisture.
      Short Term Storage
      +4°C
      Shipping
      AMBIENT
      Transportation
      Not dangerous goods
      Signal word
      Warning
      GHS Symbol
      GHS07
      Hazard statements
      H302
      Description
      Mixed isomers of carboxytetramethylrhodamine free acid. Tetramethylrhodamine (TMR) is one of the fluorophores most often used for preparing peptide, protein, nucleotide and nucleic acid conjugates. TMR dyes have been widely used as acceptors for FAM fluorophores in a variety of FRET studies. The dye can be coupled to primary or secondary amines via standard peptide chemistry.
      InChi
      InChI=1S/C24H22N2O3.C2H4O2/c1-25(2)15-9-11-19-21(13-15)28-22-14-16(26(3)4)10-12-20(22)24(19)18-8-6-5-7-17(18)23(27)29-24
      References
      (1) N.A. Evans et al.: J. Neurochem. 77, 476 (2001) , (2) K.L. Hess et al.: Cytometry 27, 145 (1997) , (3) W. Lutz et al.: J. Biol. Chem. 267, 1109 (1992)
      InChi Key
      VNRGODVGRCXKSJ-UHFFFAOYSA-N
      Smiles
      CC(O)=O.CN(C)C1=CC2=C(C=C1)C1(OC(=O)C3=C1C=CC=C3)C1=CC=C(C=C1O2)N(C)C

      Mixed isomers of carboxytetramethylrhodamine free acid. Tetramethylrhodamine (TMR) is one of the fluorophores most often used for preparing peptide, protein, nucleotide and nucleic acid conjugates. TMR dyes have been widely used as acceptors for FAM fluorophores in a variety of FRET studies. The dye can be coupled to primary or secondary amines via standard peptide chemistry.

      SKU: C0038 Category: Fluorescent Detection
      • Additional information

      Additional information

      Synonyms

      5(6)-Carboxytetramethylrhodamine, 150347-56-1

      Purity

      ≥85% (sum of isomers, HPCE)

      Appearance

      Dark red to brown powder

      CAS-Number

      98181-63-6

      Molecular Formula

      C25H22N2O5

      Molecular Weight

      430.45

      Identity

      1H-NMR

      Solvents

      DMSO, DMF, methanol, aqueous buffers (pH ≥65)

      Melting Point

      ≥300 °C

      Fluorescence

      λex 543 nm, λem 572 nm in methanol

      Smiles

      CC(O)=O.CN(C)C1=CC2=C(C=C1)C1(OC(=O)C3=C1C=CC=C3)C1=CC=C(C=C1O2)N(C)C

      InChi Key

      VNRGODVGRCXKSJ-UHFFFAOYSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      +4°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at +4°C.

      Hazard statements

      H302

      GHS Symbol

      GHS07

      Signal word

      Warning

      Transportation

      Not dangerous goods

      References

      (1) N.A. Evans et al.: J. Neurochem. 77, 476 (2001), (2) K.L. Hess et al.: Cytometry 27, 145 (1997), (3) W. Lutz et al.: J. Biol. Chem. 267, 1109 (1992)

      InChi

      InChI=1S/C24H22N2O3.C2H4O2/c1-25(2)15-9-11-19-21(13-15)28-22-14-16(26(3)4)10-12-20(22)24(19)18-8-6-5-7-17(18)23(27)29-24

      Quantity

      100 mg, 2 g, Bulk

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