Available from stock

5(6)-TAMRA

SKU: C0038

Categories: Fluorescent Detection, Fluorescent Detection

Synonyms: 5(6)-Carboxytetramethylrhodamine , 150347-56-1; 98181-63-6
CAS-Number: C₂₅H₂₂N₂O₅
Molecular Formula: 430.45
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥95% (HPLC)
Appearance: Dark red to brown powder
Identity: 1H-NMR

Properties

Solvents: DMSO, DMF, methanol, aqueous buffers (pH ≥65)
Melting Point: ≥300 °C
Fluorescence: λex 543 nm, λem 572 nm in methanol

Documentation

Safety Data Sheet (SDS): CDX C0038 MSDS.pdf

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: +4°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at +4°C.

Hazard statements: H302
GHS Symbol: GHS07
Signal word: Warning
Transportation: Not dangerous goods

Description: Mixed isomers of carboxytetramethylrhodamine free acid. Tetramethylrhodamine (TMR) is one of the fluorophores most often used for preparing peptide, protein, nucleotide and nucleic acid conjugates. TMR dyes have been widely used as acceptors for FAM fluorophores in a variety of FRET studies. The dye can be coupled to primary or secondary amines via standard peptide chemistry.
Smiles: CC(O)=O.CN(C)C1=CC2=C(C=C1)C1(OC(=O)C3=C1C=CC=C3)C1=CC=C(C=C1O2)N(C)C
InChi Key: VNRGODVGRCXKSJ-UHFFFAOYSA-N
References: (1) N.A. Evans et al.: J. Neurochem. 77, 476 (2001) , (2) K.L. Hess et al.: Cytometry 27, 145 (1997) , (3) W. Lutz et al.: J. Biol. Chem. 267, 1109 (1992)
InChi: InChI=1S/C24H22N2O3.C2H4O2/c1-25(2)15-9-11-19-21(13-15)28-22-14-16(26(3)4)10-12-20(22)24(19)18-8-6-5-7-17(18)23(27)29-24

Mixed isomers of carboxytetramethylrhodamine free acid. Tetramethylrhodamine (TMR) is one of the fluorophores most often used for preparing peptide, protein, nucleotide and nucleic acid conjugates. TMR dyes have been widely used as acceptors for FAM fluorophores in a variety of FRET studies. The dye can be coupled to primary or secondary amines via standard peptide chemistry.

SKU: C0038 Categories: Fluorescent Detection, Fluorescent Detection

Additional information

Additional information

Synonyms	5(6)-Carboxytetramethylrhodamine, 150347-56-1
Purity	≥95% (HPLC)
Appearance	Dark red to brown powder
CAS-Number	98181-63-6
Molecular Formula	C25H22N2O5
Molecular Weight	430.45
Identity	1H-NMR
Solvents	DMSO, DMF, methanol, aqueous buffers (pH ≥65)
Melting Point	≥300 °C
Fluorescence	λex 543 nm, λem 572 nm in methanol
Smiles	CC(O)=O.CN(C)C1=CC2=C(C=C1)C1(OC(=O)C3=C1C=CC=C3)C1=CC=C(C=C1O2)N(C)C
InChi Key	VNRGODVGRCXKSJ-UHFFFAOYSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at +4°C.
Hazard statements	H302
GHS Symbol	GHS07
Signal word	Warning
Transportation	Not dangerous goods
References	(1) N.A. Evans et al.: J. Neurochem. 77, 476 (2001), (2) K.L. Hess et al.: Cytometry 27, 145 (1997), (3) W. Lutz et al.: J. Biol. Chem. 267, 1109 (1992)
InChi	InChI=1S/C24H22N2O3.C2H4O2/c1-25(2)15-9-11-19-21(13-15)28-22-14-16(26(3)4)10-12-20(22)24(19)18-8-6-5-7-17(18)23(27)29-24
Quantity	100 mg, 2 g, Bulk