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    O-Phosphorylethanolamine

    Available from stock

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      O-Phosphorylethanolamine

      SKU
      C0021

      Category: Lipids, Fatty Acids

      Synonyms
      Colaminephosphoric acid , 2-Aminoethyl dihydrogen phosphate , O-Phosphocolamine , O-Phosphoethanolamine , Monoaminoethyl Phosphate , NSC 254167 , PE-104 , PEA
      1071-23-4
      CAS-Number
      C2H8NO4P
      Molecular Formula
      141.06
      Molecular Weight

      For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥98% (HPLC)
      Appearance
      White to off-white powder
      Identity
      1H-NMR

      Properties

      Solvents
      water (50mg/ml).
      Melting Point
      241 - 243 °C
      Shipping
      AMBIENT
      Short Term Storage
      RT
      Long Term Storage
      -20°C
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at -20°C.
      Hazard statements
      H314
      Precautionary statements
      P280-P305 + P351 + P338-P310
      GHS Symbol
      GHS05
      RIDADR
      UN 3261 8
      Transportation
      Packing Group II
      Description
      Phosphorylethanolamine is an ethanolamine derivative that is used in the synthesis of two different categories of phospholipids, glycerophospholipid and sphingophospholipid. It is used as an artificial AP-substrate in a TAMRA/TAMRA fluorescence-quenching assay. Newly discovered “phosphoethanolamine cellulose” has been shown to regulate biofilm matrix architecture and function and might be important understanding bacterial biofilms and for the generation of new cellulosic materials. Synthetic phosphorylethanolamine (PHO-S) has recently demonstrated cytotoxic activity on melanoma tumor cells associated with apoptotic effects, without any effect on normal cells, as such human normal endothelial, fibroblasts and lymphocytes cells. It has shown to have in vitro and in vivo anti-leukemia effects.
      Smiles
      OP(OCCN)(O)=O
      InChi Key
      SUHOOTKUPISOBE-UHFFFAOYSA-N
      References
      (1) A.T. Myller, et al., Appl. Surf. Sci. 257, 1616 (2010) , (2) A.K. Ferreira, et al., Br. J. Cancer 109, 2819 (2013) , (3) A. Shiba, et al., Sensors 17, E1877 (2017) , (4) A.C.L. Luna, et al., BMC Res. Notes 11, 126 (2018) , (5) W. Thongsomboon, et al., Science 359, 334 (2018)

      Phosphorylethanolamine is an ethanolamine derivative that is used in the synthesis of two different categories of phospholipids, glycerophospholipid and sphingophospholipid. It is used as an artificial AP-substrate in a TAMRA/TAMRA fluorescence-quenching assay. Newly discovered “phosphoethanolamine cellulose” has been shown to regulate biofilm matrix architecture and function and might be important understanding bacterial biofilms and for the generation of new cellulosic materials. Synthetic phosphorylethanolamine (PHO-S) has recently demonstrated cytotoxic activity on melanoma tumor cells associated with apoptotic effects, without any effect on normal cells, as such human normal endothelial, fibroblasts and lymphocytes cells. It has shown to have in vitro and in vivo anti-leukemia effects.

      SKU: C0021 Category: Lipids, Fatty Acids
      • Additional information

      Additional information

      Synonyms

      Colaminephosphoric acid, 2-Aminoethyl dihydrogen phosphate, O-Phosphocolamine, O-Phosphoethanolamine, Monoaminoethyl Phosphate, NSC 254167, PE-104, PEA

      Purity

      ≥98% (HPLC)

      Appearance

      White to off-white powder

      CAS-Number

      1071-23-4

      Molecular Formula

      C2H8NO4P

      Molecular Weight

      141.06

      Identity

      1H-NMR

      Solvents

      water (50mg/ml).

      Melting Point

      241 – 243 °C

      Smiles

      OP(OCCN)(O)=O

      InChi Key

      SUHOOTKUPISOBE-UHFFFAOYSA-N

      Shipping

      AMBIENT

      Short Term Storage

      RT

      Long Term Storage

      -20°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at -20°C.

      Hazard statements

      H314

      Precautionary statements

      P280-P305 + P351 + P338-P310

      GHS Symbol

      GHS05

      RIDADR

      UN 3261 8

      Transportation

      Packing Group II

      References

      (1) A.T. Myller, et al., Appl. Surf. Sci. 257, 1616 (2010), (2) A.K. Ferreira, et al., Br. J. Cancer 109, 2819 (2013), (3) A. Shiba, et al., Sensors 17, E1877 (2017), (4) A.C.L. Luna, et al., BMC Res. Notes 11, 126 (2018), (5) W. Thongsomboon, et al., Science 359, 334 (2018)

      Quantity

      25 g, 100 g, Bulk

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