O-Phosphorylethanolamine

SKU: C0021

Category: Lipids, Fatty Acids

Synonyms: Colaminephosphoric acid , 2-Aminoethyl dihydrogen phosphate , O-Phosphocolamine , O-Phosphoethanolamine , Monoaminoethyl Phosphate , NSC 254167 , PE-104 , PEA; 1071-23-4
CAS-Number: C₂H₈NO₄P
Molecular Formula: 141.06
Molecular Weight

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98% (HPLC)
Identity: 1H-NMR
Appearance: White to off-white powder

Properties

Melting Point: 241 - 243 °C
Solvents: water (50mg/ml).

Long Term Storage: -20°C
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.
Handling Advice: Protect from light and moisture.
Short Term Storage: RT
Shipping: AMBIENT

Transportation: Packing Group II
RIDADR: UN 3261 8
GHS Symbol: GHS05
Precautionary statements: P280-P305 + P351 + P338-P310
Hazard statements: H314

Description: Phosphorylethanolamine is an ethanolamine derivative that is used in the synthesis of two different categories of phospholipids, glycerophospholipid and sphingophospholipid. It is used as an artificial AP-substrate in a TAMRA/TAMRA fluorescence-quenching assay. Newly discovered “phosphoethanolamine cellulose” has been shown to regulate biofilm matrix architecture and function and might be important understanding bacterial biofilms and for the generation of new cellulosic materials. Synthetic phosphorylethanolamine (PHO-S) has recently demonstrated cytotoxic activity on melanoma tumor cells associated with apoptotic effects, without any effect on normal cells, as such human normal endothelial, fibroblasts and lymphocytes cells. It has shown to have in vitro and in vivo anti-leukemia effects.
References: (1) A.T. Myller, et al., Appl. Surf. Sci. 257, 1616 (2010) , (2) A.K. Ferreira, et al., Br. J. Cancer 109, 2819 (2013) , (3) A. Shiba, et al., Sensors 17, E1877 (2017) , (4) A.C.L. Luna, et al., BMC Res. Notes 11, 126 (2018) , (5) W. Thongsomboon, et al., Science 359, 334 (2018)
InChi Key: SUHOOTKUPISOBE-UHFFFAOYSA-N
Smiles: OP(OCCN)(O)=O

Phosphorylethanolamine is an ethanolamine derivative that is used in the synthesis of two different categories of phospholipids, glycerophospholipid and sphingophospholipid. It is used as an artificial AP-substrate in a TAMRA/TAMRA fluorescence-quenching assay. Newly discovered “phosphoethanolamine cellulose” has been shown to regulate biofilm matrix architecture and function and might be important understanding bacterial biofilms and for the generation of new cellulosic materials. Synthetic phosphorylethanolamine (PHO-S) has recently demonstrated cytotoxic activity on melanoma tumor cells associated with apoptotic effects, without any effect on normal cells, as such human normal endothelial, fibroblasts and lymphocytes cells. It has shown to have in vitro and in vivo anti-leukemia effects.

SKU: C0021 Category: Lipids, Fatty Acids

Additional information

Additional information

Synonyms	Colaminephosphoric acid, 2-Aminoethyl dihydrogen phosphate, O-Phosphocolamine, O-Phosphoethanolamine, Monoaminoethyl Phosphate, NSC 254167, PE-104, PEA
Purity	≥98% (HPLC)
Appearance	White to off-white powder
CAS-Number	1071-23-4
Molecular Formula	C2H8NO4P
Molecular Weight	141.06
Identity	1H-NMR
Solvents	water (50mg/ml).
Melting Point	241 – 243 °C
Smiles	OP(OCCN)(O)=O
InChi Key	SUHOOTKUPISOBE-UHFFFAOYSA-N
Shipping	AMBIENT
Short Term Storage	RT
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Hazard statements	H314
Precautionary statements	P280-P305 + P351 + P338-P310
GHS Symbol	GHS05
RIDADR	UN 3261 8
Transportation	Packing Group II
References	(1) A.T. Myller, et al., Appl. Surf. Sci. 257, 1616 (2010), (2) A.K. Ferreira, et al., Br. J. Cancer 109, 2819 (2013), (3) A. Shiba, et al., Sensors 17, E1877 (2017), (4) A.C.L. Luna, et al., BMC Res. Notes 11, 126 (2018), (5) W. Thongsomboon, et al., Science 359, 334 (2018)
Quantity	25 g, 100 g, Bulk