- ≥95% (HPCE)
- λex 364 nm, λem 476 nm in 0.1 M phosphate pH 7.0
- water, DMSO
Category: Fluorescent Detection
The highly fluorescent label 4-acetylamino-1,8-naphthalimide-N-caproic acid has two fused benzene rings containing a closed anhydride ring and therefore is a flat and planar molecule which can easily intercalate or act as a groove binder with DNA/RNA sequences. For the study of in situ hydridization with complementary synthetic oligonucleotides (ODNs), tagging with non-radioactive labels has gained importance, not only for medical diagnostics or clinical genetics, but also detection and isolation of DNA for research purposes. The pentamethylene chain in 6 acts as a linker molecule and keeps the target at a reasonable distance to avoid direct interaction with oligonucleotides.
λex 364 nm, λem 476 nm in 0.1 M phosphate pH 7.0
|Short Term Storage|
|Long Term Storage|
Protect from light and moisture.
|Use / Stability|
Stable for at least 2 years after receipt when stored at -20°C.
Not dangerous goods
(1) K. Misra et al.: Radiobiol. Bio-Med. Res. 129 (2004), (2) R.W. Odd et al.: Blackwell Scientific Publication, 317 (1992), (3) R.J. Kaiser et al.: Nucleic Acids Research 17, 6087 (1989)
10 mg, 50 mg, Bulk