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    6-Aminoseleno-D-luciferin

    Available from stock

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      6-Aminoseleno-D-luciferin

      SKU
      A0307

      Categories: Fluorescent Detection, Fluorescent Detection

      Synonyms
      (S)-2-(6-aminobenzo[d]thiazol-2-yl)- 4,5-dihydro-1,3-selenazole-4-carboxylic acid , (4S)?-2-?(6-?Amino-?2-?benzothiazolyl)?-?4,?5-?dihydro-?4-?delenazolecarboxylic acid
      1375964-28-5
      CAS-Number
      C11H9N3O2SSe
      Molecular Formula
      326.23
      Molecular Weight

      For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥90% (HPLC)
      Appearance
      Dark brown solid
      Identity
      1H-NMR

      Properties

      Solvents
      DMSO, water (slightly)
      Shipping
      AMBIENT
      Short Term Storage
      +4°C
      Long Term Storage
      -20°C
      Handling Advice
      Protect from light and moisture.
      Use / Stability
      Stable for at least 2 years after receipt when stored at -20°C.
      GHS Symbol
      GHS07
      Signal word
      Warning
      Transportation
      Not dangerous goods
      Description
      Firefly luciferase substrate. Selenium analog of firefly L-luciferin with red-shifted bioluminescence emission for use in in vivo bioluminescence imaging. Bioluminescence spectra: ≤ 600nm. This selenium analog exhibits a similar substrate affinity to wild type D-luciferin, though with slightly lower quantum yield.
      Smiles
      NC1=CC=C2C(SC(C3=N[C@@H](C(O)=O)C[Se]3)=N2)=C1
      InChi Key
      AQIRXTPMSNSUTJ-UHFFFAOYSA-N
      References
      (1) N.R. Conley, et al. , Angew. Chem. Int. Ed. Engl. 51, 3350 (2012) , (2) D.M. Mofford, et al. , JACS 136, 13277 (2014) , (3) S.T. Adams & S.C. Miller , Curr. Opin. Chem. Biol. 21, 112 (2014)

      Firefly luciferase substrate. Selenium analog of firefly L-luciferin with red-shifted bioluminescence emission for use in in vivo bioluminescence imaging. Bioluminescence spectra: ≤ 600nm. This selenium analog exhibits a similar substrate affinity to wild type D-luciferin, though with slightly lower quantum yield.

      SKU: A0307 Categories: Fluorescent Detection, Fluorescent Detection
      • Additional information

      Additional information

      Synonyms

      (S)-2-(6-aminobenzo[d]thiazol-2-yl)- 4,5-dihydro-1,3-selenazole-4-carboxylic acid, (4S)?-2-?(6-?Amino-?2-?benzothiazolyl)?-?4,?5-?dihydro-?4-?delenazolecarboxylic acid

      Purity

      ≥90% (HPLC)

      Appearance

      Dark brown solid

      CAS-Number

      1375964-28-5

      Molecular Formula

      C11H9N3O2SSe

      Molecular Weight

      326.23

      Identity

      1H-NMR

      Solvents

      DMSO, water (slightly)

      Smiles

      NC1=CC=C2C(SC(C3=N[C@@H](C(O)=O)C[Se]3)=N2)=C1

      InChi Key

      AQIRXTPMSNSUTJ-UHFFFAOYSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      -20°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at -20°C.

      GHS Symbol

      GHS07

      Signal word

      Warning

      Transportation

      Not dangerous goods

      References

      (1) N.R. Conley, et al., Angew. Chem. Int. Ed. Engl. 51, 3350 (2012), (2) D.M. Mofford, et al., JACS 136, 13277 (2014), (3) S.T. Adams & S.C. Miller, Curr. Opin. Chem. Biol. 21, 112 (2014)

      Quantity

      1 mg, 5 mg, Bulk

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