Specifications
- Purity
- ≥99% (NMR)
- Appearance
- Yellow powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO, DMF, acetone
- Melting Point
- 223-226 °C
- Fluorescence
- λex 351 nm, λem 430 nm in methanol
Documentation
- Safety Data Sheet (SDS)
- CDX A0021 MSDS.pdf
Available from stock
7-Amino-4-methylcoumarin
- SKU
- A0021
Categories: Fluorescent Detection, Fluorescent Detection
- Synonyms
- AMC , Coumarin 120
- 26093-31-2
- CAS-Number
- C10H9NO2
- Molecular Formula
- 175.18
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- +4°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at +4°C.
- Hazard statements
- H315, H319, H335
- Precautionary statements
- P261, P305 + P351 + P338
- GHS Symbol
- GHS07
- Signal word
- Warning
- Transportation
- Not dangerous goods
- Description
- Widely used fluorophore well-known for preparing fluorogenic 7-Amido-4-methylcoumarin (AMC) substrates for cystine aminopeptidase and other hydrolases. Used as reference compound in enzyme assays.
- Smiles
- CC1=CC(=O)OC2=C1C=CC(N)=C2
- InChi Key
- GLNDAGDHSLMOKX-UHFFFAOYSA-N
- References
- (1) M. Yodoshi et al.: J. Chrom. 1203(2), 137 (2008) , (2) K.L. Kage et al.: J. of Neuroscience Meth. 161(1), 47 (2007) , (3) Y. Kanaoka et al.: Chem. Pharm. Bull. 30, 1485 (1982) , (4) S. Khammungkhune et al.: Synthesis 8, 614 (1980)
- InChi
- InChI=1S/C10H9NO2/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3
Widely used fluorophore well-known for preparing fluorogenic 7-Amido-4-methylcoumarin (AMC) substrates for cystine aminopeptidase and other hydrolases. Used as reference compound in enzyme assays.
Additional information
| Synonyms | AMC, Coumarin 120 |
|---|---|
| Purity | ≥99% (NMR) |
| Appearance | Yellow powder |
| CAS-Number | 26093-31-2 |
| Molecular Formula | C10H9NO2 |
| Molecular Weight | 175.18 |
| Identity | 1H-NMR |
| Solvents | DMSO, DMF, acetone |
| Melting Point | 223-226 °C |
| Fluorescence | λex 351 nm, λem 430 nm in methanol |
| Smiles | CC1=CC(=O)OC2=C1C=CC(N)=C2 |
| InChi Key | GLNDAGDHSLMOKX-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Hazard statements | H315, H319, H335 |
| Precautionary statements | P261, P305 + P351 + P338 |
| GHS Symbol | GHS07 |
| Signal word | Warning |
| Transportation | Not dangerous goods |
| References | (1) M. Yodoshi et al.: J. Chrom. 1203(2), 137 (2008), (2) K.L. Kage et al.: J. of Neuroscience Meth. 161(1), 47 (2007), (3) Y. Kanaoka et al.: Chem. Pharm. Bull. 30, 1485 (1982), (4) S. Khammungkhune et al.: Synthesis 8, 614 (1980) |
| InChi | InChI=1S/C10H9NO2/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3 |
| Quantity | 250 mg, 10 g, Bulk |
