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    7-Amino-4-methylcoumarin

    Available from stock

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      7-Amino-4-methylcoumarin

      SKU
      A0021

      Category: Fluorescent Detection

      Synonyms
      AMC , Coumarin 120
      26093-31-2
      CAS-Number
      C10H9NO2
      Molecular Formula
      175.18
      Molecular Weight

      • Product Data
      • Handling
      • Safety Information
      • Details

      Specifications

      Purity
      ≥99% (NMR)
      Identity
      1H-NMR
      Appearance
      Yellow powder

      Properties

      Fluorescence
      λex 351 nm, λem 430 nm in methanol
      Melting Point
      223-226 °C
      Solvents
      DMSO, DMF, acetone

      Downloads

      Safety Data Sheet
      CDX A0021 MSDS.pdf
      Long Term Storage
      +4°C
      Use / Stability
      Stable for at least 2 years after receipt when stored at +4°C.
      Handling Advice
      Protect from light and moisture.
      Short Term Storage
      +4°C
      Shipping
      AMBIENT
      Transportation
      Not dangerous goods
      Signal word
      Warning
      GHS Symbol
      GHS07
      Precautionary statements
      P261, P305 + P351 + P338
      Hazard statements
      H315, H319, H335
      Description
      Widely used fluorophore well-known for preparing fluorogenic 7-Amido-4-methylcoumarin (AMC) substrates for cystine aminopeptidase and other hydrolases. Used as reference compound in enzyme assays.
      InChi
      InChI=1S/C10H9NO2/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3
      References
      (1) M. Yodoshi et al.: J. Chrom. 1203(2), 137 (2008) , (2) K.L. Kage et al.: J. of Neuroscience Meth. 161(1), 47 (2007) , (3) Y. Kanaoka et al.: Chem. Pharm. Bull. 30, 1485 (1982) , (4) S. Khammungkhune et al.: Synthesis 8, 614 (1980)
      InChi Key
      GLNDAGDHSLMOKX-UHFFFAOYSA-N
      Smiles
      CC1=CC(=O)OC2=C1C=CC(N)=C2

      Widely used fluorophore well-known for preparing fluorogenic 7-Amido-4-methylcoumarin (AMC) substrates for cystine aminopeptidase and other hydrolases. Used as reference compound in enzyme assays.

      SKU: A0021 Category: Fluorescent Detection
      • Additional information

      Additional information

      Synonyms

      AMC, Coumarin 120

      Purity

      ≥99% (NMR)

      Appearance

      Yellow powder

      CAS-Number

      26093-31-2

      Molecular Formula

      C10H9NO2

      Molecular Weight

      175.18

      Identity

      1H-NMR

      Solvents

      DMSO, DMF, acetone

      Melting Point

      223-226 °C

      Fluorescence

      λex 351 nm, λem 430 nm in methanol

      Smiles

      CC1=CC(=O)OC2=C1C=CC(N)=C2

      InChi Key

      GLNDAGDHSLMOKX-UHFFFAOYSA-N

      Shipping

      AMBIENT

      Short Term Storage

      +4°C

      Long Term Storage

      +4°C

      Handling Advice

      Protect from light and moisture.

      Use / Stability

      Stable for at least 2 years after receipt when stored at +4°C.

      Hazard statements

      H315, H319, H335

      Precautionary statements

      P261, P305 + P351 + P338

      GHS Symbol

      GHS07

      Signal word

      Warning

      Transportation

      Not dangerous goods

      References

      (1) M. Yodoshi et al.: J. Chrom. 1203(2), 137 (2008), (2) K.L. Kage et al.: J. of Neuroscience Meth. 161(1), 47 (2007), (3) Y. Kanaoka et al.: Chem. Pharm. Bull. 30, 1485 (1982), (4) S. Khammungkhune et al.: Synthesis 8, 614 (1980)

      InChi

      InChI=1S/C10H9NO2/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3

      Quantity

      250 mg, 10 g, Bulk

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