Balofloxacin

SKU: B0302

Category: Antibiotics

Synonyms: (±)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[3-(methylamino)piperidino]-4-oxo-3-quinolinecarboxylic acid; 127294-70-6
CAS-Number: C₂₀H₂₄FN₃O₄
Molecular Formula: 389.42
Molecular Weight

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98% (HPLC)
Identity: UV/Vis
Appearance: White powder

Properties

Melting Point: 181-187 °C
Solvents: DMSO (10mg/ml)

Shipping: AMBIENT
Use / Stability: Stable for at least 2 years after receipt when stored at +4°C.
Handling Advice: Protect from light and moisture.
Long Term Storage: +4°C
Short Term Storage: +4°C

Transportation: Not dangerous goods

Description: Fluoroquinolone antibiotic with potent bactericidal activity. Inhibits the synthesis of bacterial DNA by interfering with the the supercoiling activity of DNA gyrase.
References: (1) T. Ito, et al. , Antimicrob. Agents Chemother. 36, 1708 (1992) , (2) I. Takashima, et al. , Antimicrob. Agents Chemother. 37, 901 (1993) , (3) Y. Gohara, et al. , Antimicrob. Agents Chemother. 37, 1826 (1993) , (4) T. Ito, et al. , Biol. Pharm. Bull. 17, 927 (1994) , (5) N. Cho, et al. , Drugs 49, 391 (1995) , (6) H. Iwasaki, et al. , Chemotherapy 41, 100 (1995) , (7) T. Ito, et al. , Antimicrob. Agents Chemother. 39, 1522 (1995) , (8) L. Alksne , Curr. Opin. Investig. Drugs 4, 224 (2003) , (9) H. Jiang, et al. , J. Ocul. Pharmacol. Ther. 30, 482 (2014)
InChi Key: MGQLHRYJBWGORO-UHFFFAOYSA-N
Smiles: CNC(CCC1)CN1C2=C(F)C=C3C(N(C4CC4)C=C(C(O)=O)C3=O)=C2OC

Fluoroquinolone antibiotic with potent bactericidal activity. Inhibits the synthesis of bacterial DNA by interfering with the the supercoiling activity of DNA gyrase.

SKU: B0302 Category: Antibiotics

Additional information

Additional information

Synonyms	(±)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[3-(methylamino)piperidino]-4-oxo-3-quinolinecarboxylic acid
Purity	≥98% (HPLC)
Appearance	White powder
CAS-Number	127294-70-6
Molecular Formula	C20H24FN3O4
Molecular Weight	389.42
Identity	UV/Vis
Solvents	DMSO (10mg/ml)
Melting Point	181-187 °C
Smiles	CNC(CCC1)CN1C2=C(F)C=C3C(N(C4CC4)C=C(C(O)=O)C3=O)=C2OC
InChi Key	MGQLHRYJBWGORO-UHFFFAOYSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at +4°C.
Transportation	Not dangerous goods
References	(1) T. Ito, et al., Antimicrob. Agents Chemother. 36, 1708 (1992), (2) I. Takashima, et al., Antimicrob. Agents Chemother. 37, 901 (1993), (3) Y. Gohara, et al., Antimicrob. Agents Chemother. 37, 1826 (1993), (4) T. Ito, et al., Biol. Pharm. Bull. 17, 927 (1994), (5) N. Cho, et al., Drugs 49, 391 (1995), (6) H. Iwasaki, et al., Chemotherapy 41, 100 (1995), (7) T. Ito, et al., Antimicrob. Agents Chemother. 39, 1522 (1995), (8) L. Alksne, Curr. Opin. Investig. Drugs 4, 224 (2003), (9) H. Jiang, et al., J. Ocul. Pharmacol. Ther. 30, 482 (2014)
Quantity	25 mg, 100 mg, Bulk