Specifications
- Purity
- ≥97% (HPLC)
- Identity
- 1H-NMR
- Appearance
- White powder
Properties
- Melting Point
- 102-104 °C
- Solvents
- water
Available from stock
BEP
- SKU
- B0040
Category: Building Blocks, Intermediates, Reagents
- Synonyms
- 2-Bromo-1-ethyl-pyridinium tetrafluoroborate
- 878-23-9
- CAS-Number
- C7H9BrNBF4
- Molecular Formula
- 273.86
- Molecular Weight
- Shipping
- AMBIENT
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Handling Advice
- Protect from light and moisture.
- Long Term Storage
- -20°C
- Short Term Storage
- +4°C
- Transportation
- Not dangerous goods
- Description
- Efficient coupling reagent for the synthesis of sterically hindered amides, especially peptides. In terms of reactivity and racemization-suppressing capability, this pyridinium-type reagent, BEP, proved to be more efficient than commonly used uronium- and phosphonium-type reagents, such as HBTU, BOP, and PyBroP, for the synthesis of hindered peptides containing N-methylated or C?,C?-dialkylated amino acid residues. BEP was also proven to be an efficient reagent for the synthesis of esters, especially active esters and hindered esters, and tert-butyl esters.
- InChi
- InChI=1S/C7H9BrN.BF4/c1-2-9-6-4-3-5-7(9)8
- InChi Key
- YJDXVQLBIAJTHP-UHFFFAOYSA-N
- Smiles
- CC[N]1=C(Br)C=CC=C1.FB(F)F.[F-]
Efficient coupling reagent for the synthesis of sterically hindered amides, especially peptides. In terms of reactivity and racemization-suppressing capability, this pyridinium-type reagent, BEP, proved to be more efficient than commonly used uronium- and phosphonium-type reagents, such as HBTU, BOP, and PyBroP, for the synthesis of hindered peptides containing N-methylated or C?,C?-dialkylated amino acid residues. BEP was also proven to be an efficient reagent for the synthesis of esters, especially active esters and hindered esters, and tert-butyl esters.
Additional information
| Synonyms | 2-Bromo-1-ethyl-pyridinium tetrafluoroborate |
|---|---|
| Purity | ≥97% (HPLC) |
| Appearance | White powder |
| CAS-Number | 878-23-9 |
| Molecular Formula | C7H9BrNBF4 |
| Molecular Weight | 273.86 |
| Identity | 1H-NMR |
| Solvents | water |
| Melting Point | 102-104 °C |
| Smiles | CC[N]1=C(Br)C=CC=C1.FB(F)F.[F-] |
| InChi Key | YJDXVQLBIAJTHP-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Transportation | Not dangerous goods |
| InChi | InChI=1S/C7H9BrN.BF4/c1-2-9-6-4-3-5-7(9)8 |
| Quantity | 1 g, 5 g, 25 g, Bulk |
