Specifications
- Purity
- EP
- Appearance
- White to off-white powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMC (60 mg/ml) Slightly DMSO, methanol
- Melting Point
- 140-146 °C (lit.)
Available from stock
Imidacloprid
- SKU
- I0121
Category: Insecticides
- Synonyms
- 1-(6-Chlor-3-pyridinylmethyl)-N-nitroimidazolidin-2-ylidenamin
- 138261-41-3
- CAS-Number
- C9H10ClN5O2
- Molecular Formula
- 255.66
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- +4°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Hazard statements
- H302-H410
- Precautionary statements
- P301 + P312 + P330
- GHS Symbol
- GHS07+GHS09
- Signal word
- Warning
- RIDADR
- UN3077
- Transportation
- Packing Group III
- Description
- Imidacloprid is a broad-spectrum neonicotinoid insecticide that is effective against sucking and biting insects and insects of the Coleopteran and Lepidoptera orders. It is an antagonist of the post-synaptic nicotinic receptors in the insect central nervous system, blocking acetylcholine at the post-synaptic membrane and impairing normal nerve function. It is an agonist of insect acetylcholine receptors (nAchRs) with Ki values of 1.9, 2.1, 290, and 50 nM for M. persicae and D. melanogaster receptors, rat brain membranes and rat recombinant receptors containing α4β2 subunits, respectively. In a mouse model of high-fat diet-induced obesity, imidacloprid increased body weight gain and adiposity and impairs glucose metabolism without increasing total food intake. Has been shown be to implicated in colony collapse disorder of honey bees. Can be used as a reference compound.
- Smiles
- ClC1=NC=C(CN2C(N[N+]([O-])=O)=NCC2)C=C1
- InChi Key
- YWTYJOPNNQFBPC-UHFFFAOYSA-N
- References
- (1) A. Elbert, et al., Pflanzenschutz-Nachrichten Bayer 44, 113 (1991) , (2) S. Kagabu, et al., J. Med. Chem. 43, 5003 (2000) , (3) D.-S. Wang, et al., J. Biol. Chem. 282, 16016 (2007) , (4) E. Zhang, & J.C. Nieh, J. Exp. Biol. 218, 3199 (2015) , (5) Q. Sun, et al., J. Agric. Food Chem. 64, 9293 (2016)
- InChi
- InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)
Imidacloprid is a broad-spectrum neonicotinoid insecticide that is effective against sucking and biting insects and insects of the Coleopteran and Lepidoptera orders. It is an antagonist of the post-synaptic nicotinic receptors in the insect central nervous system, blocking acetylcholine at the post-synaptic membrane and impairing normal nerve function. It is an agonist of insect acetylcholine receptors (nAchRs) with Ki values of 1.9, 2.1, 290, and 50 nM for M. persicae and D. melanogaster receptors, rat brain membranes and rat recombinant receptors containing α4β2 subunits, respectively. In a mouse model of high-fat diet-induced obesity, imidacloprid increased body weight gain and adiposity and impairs glucose metabolism without increasing total food intake. Has been shown be to implicated in colony collapse disorder of honey bees. Can be used as a reference compound.
Additional information
| Synonyms | 1-(6-Chlor-3-pyridinylmethyl)-N-nitroimidazolidin-2-ylidenamin |
|---|---|
| Purity | EP |
| Appearance | White to off-white powder |
| CAS-Number | 138261-41-3 |
| Molecular Formula | C9H10ClN5O2 |
| Molecular Weight | 255.66 |
| Identity | 1H-NMR |
| Solvents | DMC (60 mg/ml) Slightly DMSO, methanol |
| Melting Point | 140-146 °C (lit.) |
| Smiles | ClC1=NC=C(CN2C(N[N+]([O-])=O)=NCC2)C=C1 |
| InChi Key | YWTYJOPNNQFBPC-UHFFFAOYSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H302-H410 |
| Precautionary statements | P301 + P312 + P330 |
| GHS Symbol | GHS07+GHS09 |
| Signal word | Warning |
| RIDADR | UN3077 |
| Transportation | Packing Group III |
| References | (1) A. Elbert, et al., Pflanzenschutz-Nachrichten Bayer 44, 113 (1991), (2) S. Kagabu, et al., J. Med. Chem. 43, 5003 (2000), (3) D.-S. Wang, et al., J. Biol. Chem. 282, 16016 (2007), (4) E. Zhang, & J.C. Nieh, J. Exp. Biol. 218, 3199 (2015), (5) Q. Sun, et al., J. Agric. Food Chem. 64, 9293 (2016) |
| InChi | InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13) |
| Quantity | 100 mg, Bulk |
