Mancozeb

SKU: M0158

Category: Fungicides

Synonyms: Manganese Zinc ethylenebis(dithiocarbamate) , ((1,2-Ethanediylbis(carbamodithioato))(2-)) manganese mixture with (((1,2-ethanediylbis(carbamodithioato))(2-))zinc; 8018-01-7
CAS-Number: C₈H₁₂MnN₄S₈Zn
Molecular Formula: 541.08
Molecular Weight

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥94% (HPLC)
Identity: 1H-NMR
Appearance: Light grey solid

Properties

Solvents: DMSO

Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at +4°C.
Long Term Storage: +4°C
Short Term Storage: RT
Shipping: AMBIENT

Transportation: Packing Group III
RIDADR: UN3077 9
Signal word: Warning
GHS Symbol: GHS07+GHS08+GHS09
Precautionary statements: P273, P280
Hazard statements: H317, H361d, H400

Description: Mancozeb is a dithiocarbamate non-systemic agricultural fungicide with multi-site, protective action on contact. It is a combination of two dithiocarbamates: maneb and zineb. The mixture controls many fungal diseases in a wide range of field crops, fruits, nuts, vegetables and ornamentals. It reacts with, and inactivates, the sulfhydryl groups of amino acids and enzymes of fungal cell, resulting in disruption of lipid metabolism, respiration and production of adenosine triphosphate. Shown to by cytotoxic, induce apoptosis and damaging DNA on mammalian cells. also shown to have neurotoxic and genotoxic activity.
References: (1) G.Y. Nicolau, Endocrinol. 20, 249 (1982) , (2) P. Perocco, et al., Teratog. Carcinog. Mutagen. 9, 75 (1989) , (3) Y. Shukla, et al., Cancer Lett. 53, 191 (1990) , (4) C.D.S. Tomilin, The Pesticide Manual, 13th Edition (2003) , (5) G. Calviello, et al., Toxicol. Appl. Pharmacol. 211, 87 (2006) , (6) L.M. Domico, et al., Neurotoxicol. 28, 1079 (2007) , (7) A.K. Srivastava, et al., Life Sci. 90, 815 (2012) , (8) R. Iorio, et al., Toxicol. In Vitro. 30, 438 (2015)
InChi Key: CHNQZRKUZPNOOH-UHFFFAOYSA-J
Smiles: S=C(S[Zn]S1)NCCNC1=S.S=C(S[Mn]S2)NCCNC2=S

Mancozeb is a dithiocarbamate non-systemic agricultural fungicide with multi-site, protective action on contact. It is a combination of two dithiocarbamates: maneb and zineb. The mixture controls many fungal diseases in a wide range of field crops, fruits, nuts, vegetables and ornamentals. It reacts with, and inactivates, the sulfhydryl groups of amino acids and enzymes of fungal cell, resulting in disruption of lipid metabolism, respiration and production of adenosine triphosphate. Shown to by cytotoxic, induce apoptosis and damaging DNA on mammalian cells. also shown to have neurotoxic and genotoxic activity.

SKU: M0158 Category: Fungicides

Additional information

Additional information

Synonyms	Manganese Zinc ethylenebis(dithiocarbamate), ((1,2-Ethanediylbis(carbamodithioato))(2-)) manganese mixture with (((1,2-ethanediylbis(carbamodithioato))(2-))zinc
Purity	≥94% (HPLC)
Appearance	Light grey solid
CAS-Number	8018-01-7
Molecular Formula	C8H12MnN4S8Zn
Molecular Weight	541.08
Identity	1H-NMR
Solvents	DMSO
Smiles	S=C(S[Zn]S1)NCCNC1=S.S=C(S[Mn]S2)NCCNC2=S
InChi Key	CHNQZRKUZPNOOH-UHFFFAOYSA-J
Shipping	AMBIENT
Short Term Storage	RT
Long Term Storage	+4°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at +4°C.
Hazard statements	H317, H361d, H400
Precautionary statements	P273, P280
GHS Symbol	GHS07+GHS08+GHS09
Signal word	Warning
RIDADR	UN3077 9
Transportation	Packing Group III
References	(1) G.Y. Nicolau, Endocrinol. 20, 249 (1982), (2) P. Perocco, et al., Teratog. Carcinog. Mutagen. 9, 75 (1989), (3) Y. Shukla, et al., Cancer Lett. 53, 191 (1990), (4) C.D.S. Tomilin, The Pesticide Manual, 13th Edition (2003), (5) G. Calviello, et al., Toxicol. Appl. Pharmacol. 211, 87 (2006), (6) L.M. Domico, et al., Neurotoxicol. 28, 1079 (2007), (7) A.K. Srivastava, et al., Life Sci. 90, 815 (2012), (8) R. Iorio, et al., Toxicol. In Vitro. 30, 438 (2015)
Quantity	500 mg, Bulk