N-Allylthiourea
- SKU
- A0783
Category: Building Blocks, Intermediates, Reagents
- Synonyms
- ATU, 1-Allyl-2-thiourea, Thiosinamine, NSC 1915, Rhodallin, U 19571, N-2-propen-1-yl-thiourea
- 109-57-9
- CAS-Number
- C4H8N2S
- Molecular Formula
- 116.18
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Specifications
- Purity
- ≥98% (GC)
- Appearance
- Faint yellow powder
- Identity
- 1H-NMR
Properties
- Solvents
- Soluble in DMSO (30 mg/ml) or ethanol (10 mg/ml).
- Melting Point
- 70-72 °C (lit.)
- Density
- 1.11 g/mL at 25 °C (lit.)
Documentation
- Safety Data Sheet (SDS)
- CDX A0783 SDS_V1.2.pdf
- Shipping
- AMBIENT
- Short Term Storage
- RT
- Long Term Storage
- RT
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at RT.
- Hazard statements
- H301
- Precautionary statements
- P264 - P270 - P301 + P310 - P405 - P501
- GHS Symbol
- GHS06
- Signal word
- Danger
- RIDADR
- UN2811
- Transportation
- Packing Group III
- Description
- Allylthiourea (ATU) is a strong, selective inhibitor of ammonia and nitrite oxidation. Allylthiourea is commonly used to inhibit nitritation, by targeting the ammonia monooxygenase action and chelating the copper in the active site (concentration 8-80µM), ultimately hindering its function. Nitritation inhibition has been used in micropollutant biodegradability studies and in studies investigating nitritation kinetics and activity. Allylthiourea is also a potent inhibitor of methane monooxygenase (MMO).
- Smiles
- NC(=S)NCC=C
- References
- (1) C. Bedard, & R. Knowles, Microbiol. Rev. 53, 68 (1989) , (2) P. Ginestet, et al., Appl. Environ. Microbiol. 64, 2266 (1998) , (3) Y. Yu, et al., Appl. Microbiol. Biotechnol. 82, 333 (2009) , (4) K. Tatari, et al., Chemosphere 182, 301 (2017)
Allylthiourea (ATU) is a strong, selective inhibitor of ammonia and nitrite oxidation. Allylthiourea is commonly used to inhibit nitritation, by targeting the ammonia monooxygenase action and chelating the copper in the active site (concentration 8-80µM), ultimately hindering its function. Nitritation inhibition has been used in micropollutant biodegradability studies and in studies investigating nitritation kinetics and activity. Allylthiourea is also a potent inhibitor of methane monooxygenase (MMO).