Specifications
- Purity
- ≥95% (NMR)
- Appearance
- Red powder
- Identity
- 1H-NMR
Properties
- Solvents
- Soluble in DMSO or chloroform.
- Melting Point
- 206 - 210 °C (lit.)
Category: Building Blocks, Intermediates, Reagents
Woollins′ Reagent is an organophosphorus compound that finds widespread utilization as a reagent in organic synthesis. Woollins′ Reagent participates in diverse reactions, such as yielding spiro heterocycles when combined with benzoic hydrazides, generating secondary amines, forming 10-membered phosphorus-selenium heterocycles in conjunction with aromatic diols, and facilitating ring-opening deselenation and phosphorus-phosphorus coupling. Woollins′ Reagent has contributed to the synthesis of biologically active compounds, including anticancer drugs, antibiotics and antiviral agents.
Synonyms | 2,4-Diphenyl-1,3-diselenadiphosphetane 2,4-diselenide |
---|---|
Purity | ≥95% (NMR) |
Appearance | Red powder |
CAS-Number | 122039-27-4 |
Molecular Formula | C12H10P2Se4 |
Molecular Weight | 532.00 |
Identity | 1H-NMR |
Solvents | Soluble in DMSO or chloroform. |
Melting Point | 206 – 210 °C (lit.) |
Smiles | [Se]=P([Se]1)(C2=CC=CC=C2)[Se]P1(C3=CC=CC=C3)=[Se] |
InChi Key | GKYFQRQKPYPLGJ-UHFFFAOYSA-N |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | +4°C |
Handling Advice | Very hygroscopic. Store under inert gas. |
Use / Stability | Stable for at least 2 years after receipt when stored at +4°C. |
Hazard statements | H301 + H331 – H373 – H410 |
Precautionary statements | P273 – P301 + P310 + P330 – P304 + P340 + P311 – P314 |
GHS Symbol | GHS06+GHS08+GHS09 |
Signal word | Danger |
RIDADR | UN3283 |
Transportation | Packing Group III |
References | (1) G. Hua, et al., Org. Lett. 8, 525 (2006), (2) D.B. Cordes, et al., Acta Crystallpgr. C 67, o509 (2011), (3) G. Hua, et al., ACS Omega 5, 11744 (2020), (4) G. Hua & J.D. Woollins, ACS Omega 6, 31228 (2021), (5) L.E. English, et al., Chemistry 28, e202200376 (2022), (6) P.N. Makhal, et al., Chem Commun. 59, 3767 (2023) |
Quantity | 1 g, 5 g, Bulk |