Available from stock

N-Nitrosomorpholine (NMOR)

SKU: N0370

Category: Building Blocks, Intermediates, Reagents

Synonyms: NMOR, Nitrosomorpholine, NSC-139, BRN 0112139; 59-89-2
CAS-Number: C₄H₈N₂O₂
Molecular Formula: 116.12
Molecular Weight

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Product Data
Handling
Safety Information
Details

Specifications

Purity: ≥98% (GC)
Appearance: Yellow clear liquid
Identity: 1H-NMR

Properties

Solvents: Soluble in DMSO. Sligthly soluble in methanol.
Density: 0.79 g/cm3

Shipping: AMBIENT
Short Term Storage: +4°C
Long Term Storage: -20°C
Handling Advice: Protect from light and moisture.
Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.

Hazard statements: H301 - H351
Precautionary statements: P201 - P301 + P310 + P330
GHS Symbol: GHS06+GHS08
Signal word: Danger
RIDADR: UN2811
Transportation: Packing Group III

Description: N-Nitrosomorpholine (NMOR) is a nitrosamine and is known to be a potent carcinogen associated with cancer development in animals and humans. NMOR can damage DNA and cause mutations in genes that control cell growth and division. It reacts with DNA in vitro to form genotoxic activity, which may lead to cell death or mutagenesis. NMOR is formed in various industrial processes, including the synthesis of certain chemicals and in the preservation of cosmetic and personal care products. This compound can be used as analytical reference material. NMOR is used as a tumor initiator. It is a reagent for preparing carcinogenic animal diseases moδ NMOR has other widespread utilization in laboratory and industrial environments. NMOR exhibits potent oxidizing properties, making it valuable in various applications, including as a bulding block for synthesis, environmental monitoring, and as a reagent in laboratory settings. It serves as a vital component in the synthesis of diverse compounds and functions as an analytical reagent.
Smiles: O=NN1CCOCC1
InChi Key: ZKXDGKXYMTYWTB-UHFFFAOYSA-N
References: (1) H.S. Taper, et al., Cancer Res. 31, 913 (1971) , (2) R. Prakin, et al., Mutat. Res. 21, 155 (1973) , (3) C.E. Kimble, et al., Mutat. Res. 31, 153 (1975) , (4) K.D. Brunnemann, et al., Carcinogenesis 3, 693 (1982) , (5) J.B. Morrison & S.S. Hecht, IARC Sci. Publ. 57, 185 (1984) , (6) R.G. Klein, et al., Exp. Pathol. 40, 189 (1990) , (7) P.A. Munzel, et al., Biochem. Pharnacol. 42, 365 (1991) , (8) S. Tudzarova-Trajkovska & J. Wesierska-Gadek, J. Cell Biochem. 90, 837 (2003) , (9) S. Robichova, et al., Chem. Biol. Interact. 148, 163 (2004) , (10) C.M. Glover, et al., Water Res. 148, 306 (2019) , (11) Y. Li & S.S. Hecht, Int. J. Mol. Sci. 23, 4559 (2022) , (12) M. Bignami, et al., Efsa J. 21, e07884 (2023)

N-Nitrosomorpholine (NMOR) is a nitrosamine and is known to be a potent carcinogen associated with cancer development in animals and humans. NMOR can damage DNA and cause mutations in genes that control cell growth and division. It reacts with DNA in vitro to form genotoxic activity, which may lead to cell death or mutagenesis. NMOR is formed in various industrial processes, including the synthesis of certain chemicals and in the preservation of cosmetic and personal care products. This compound can be used as analytical reference material. NMOR is used as a tumor initiator. It is a reagent for preparing carcinogenic animal diseases moδ NMOR has other widespread utilization in laboratory and industrial environments. NMOR exhibits potent oxidizing properties, making it valuable in various applications, including as a bulding block for synthesis, environmental monitoring, and as a reagent in laboratory settings. It serves as a vital component in the synthesis of diverse compounds and functions as an analytical reagent.

SKU: N0370 Category: Building Blocks, Intermediates, Reagents

Additional information

Additional information

Synonyms	NMOR, Nitrosomorpholine, NSC-139, BRN 0112139
Purity	≥98% (GC)
Appearance	Yellow clear liquid
CAS-Number	59-89-2
Molecular Formula	C4H8N2O2
Molecular Weight	116.12
Identity	1H-NMR
Solvents	Soluble in DMSO. Sligthly soluble in methanol.
Density	0.79 g/cm3
Smiles	O=NN1CCOCC1
InChi Key	ZKXDGKXYMTYWTB-UHFFFAOYSA-N
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use / Stability	Stable for at least 2 years after receipt when stored at -20°C.
Hazard statements	H301 – H351
Precautionary statements	P201 – P301 + P310 + P330
GHS Symbol	GHS06+GHS08
Signal word	Danger
RIDADR	UN2811
Transportation	Packing Group III
References	(1) H.S. Taper, et al., Cancer Res. 31, 913 (1971), (2) R. Prakin, et al., Mutat. Res. 21, 155 (1973), (3) C.E. Kimble, et al., Mutat. Res. 31, 153 (1975), (4) K.D. Brunnemann, et al., Carcinogenesis 3, 693 (1982), (5) J.B. Morrison & S.S. Hecht, IARC Sci. Publ. 57, 185 (1984), (6) R.G. Klein, et al., Exp. Pathol. 40, 189 (1990), (7) P.A. Munzel, et al., Biochem. Pharnacol. 42, 365 (1991), (8) S. Tudzarova-Trajkovska & J. Wesierska-Gadek, J. Cell Biochem. 90, 837 (2003), (9) S. Robichova, et al., Chem. Biol. Interact. 148, 163 (2004), (10) C.M. Glover, et al., Water Res. 148, 306 (2019), (11) Y. Li & S.S. Hecht, Int. J. Mol. Sci. 23, 4559 (2022), (12) M. Bignami, et al., Efsa J. 21, e07884 (2023)
Quantity	1 g, Bulk