Specifications
- Purity
- ≥98% (GC)
- Appearance
- Yellow clear liquid
- Identity
- 1H-NMR
Properties
- Solvents
- Soluble in DMSO. Sligthly soluble in methanol.
- Density
- 0.79 g/cm3
Category: Building Blocks, Intermediates, Reagents
N-Nitrosomorpholine (NMOR) is a nitrosamine and is known to be a potent carcinogen associated with cancer development in animals and humans. NMOR can damage DNA and cause mutations in genes that control cell growth and division. It reacts with DNA in vitro to form genotoxic activity, which may lead to cell death or mutagenesis. NMOR is formed in various industrial processes, including the synthesis of certain chemicals and in the preservation of cosmetic and personal care products. This compound can be used as analytical reference material. NMOR is used as a tumor initiator. It is a reagent for preparing carcinogenic animal diseases moδ NMOR has other widespread utilization in laboratory and industrial environments. NMOR exhibits potent oxidizing properties, making it valuable in various applications, including as a bulding block for synthesis, environmental monitoring, and as a reagent in laboratory settings. It serves as a vital component in the synthesis of diverse compounds and functions as an analytical reagent.
Synonyms | NMOR, Nitrosomorpholine, NSC-139, BRN 0112139 |
---|---|
Purity | ≥98% (GC) |
Appearance | Yellow clear liquid |
CAS-Number | 59-89-2 |
Molecular Formula | C4H8N2O2 |
Molecular Weight | 116.12 |
Identity | 1H-NMR |
Solvents | Soluble in DMSO. Sligthly soluble in methanol. |
Density | 0.79 g/cm3 |
Smiles | O=NN1CCOCC1 |
InChi Key | ZKXDGKXYMTYWTB-UHFFFAOYSA-N |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Hazard statements | H301 – H351 |
Precautionary statements | P201 – P301 + P310 + P330 |
GHS Symbol | GHS06+GHS08 |
Signal word | Danger |
RIDADR | UN2811 |
Transportation | Packing Group III |
References | (1) H.S. Taper, et al., Cancer Res. 31, 913 (1971), (2) R. Prakin, et al., Mutat. Res. 21, 155 (1973), (3) C.E. Kimble, et al., Mutat. Res. 31, 153 (1975), (4) K.D. Brunnemann, et al., Carcinogenesis 3, 693 (1982), (5) J.B. Morrison & S.S. Hecht, IARC Sci. Publ. 57, 185 (1984), (6) R.G. Klein, et al., Exp. Pathol. 40, 189 (1990), (7) P.A. Munzel, et al., Biochem. Pharnacol. 42, 365 (1991), (8) S. Tudzarova-Trajkovska & J. Wesierska-Gadek, J. Cell Biochem. 90, 837 (2003), (9) S. Robichova, et al., Chem. Biol. Interact. 148, 163 (2004), (10) C.M. Glover, et al., Water Res. 148, 306 (2019), (11) Y. Li & S.S. Hecht, Int. J. Mol. Sci. 23, 4559 (2022), (12) M. Bignami, et al., Efsa J. 21, e07884 (2023) |
Quantity | 1 g, Bulk |