Specifications
- Purity
- ≥95% (NMR)
- Appearance
- Pale pink powder
- Identity
- 1H-NMR
Properties
- Solvents
- Soluble in DMF or DMSO.
- Melting Point
- 250-252 °C (lit.)
- Fluorescence
- λex 594 nm, λem 663 nm in 0.1 M Tris pH 9.0 (esterase)
Category: Fluorescent Detection, Fluorescent Detection
S-Nitroso-L-glutathione is an S-nitrosothiol NO donor based on naturally-occurring glutathione. It is a potent smooth muscle relaxant and inhibitor of platelet aggregation. Its stability in solution varies from seconds to hours depending on temperature, buffer composition and metal content.
Synonyms | Naphtholfluorescein DA |
---|---|
Purity | ≥95% (NMR) |
Appearance | Pale pink powder |
CAS-Number | 77084-71-0 |
Molecular Formula | C32H20O7 |
Molecular Weight | 516.50 |
Identity | 1H-NMR |
Solvents | Soluble in DMF or DMSO. |
Melting Point | 250-252 °C (lit.) |
Fluorescence | λex 594 nm, λem 663 nm in 0.1 M Tris pH 9.0 (esterase) |
Smiles | CC(OC1=CC2=CC=C3C(OC(C(C=CC(OC(C)=O)=C4)=C4C=C5)=C5C36OC(C7=C6C=CC=C7)=O)=C2C=C1)=O |
InChi Key | CIFWTDOEMTUUAO-UHFFFAOYSA-N |
Shipping | AMBIENT |
Short Term Storage | -20°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Transportation | Not dangerous goods |
References | (1) M.W. Radomski, et al.; Br. J. Pharmacol. 107, 745 (1992), (2) W.R. Mathews & S.W. Kerr; J. Pharmacol. Exp. Ther. 267, 1529 (1993), (1) E.A. Konorev, et al.; J. Pharmacol. Exp. Ther. 274, 200 (1995), (4) A. Gasco, et al.; Farmaco 51, 617 (1996), (5) J.A. Cook, et al.; Anal. Biochem. 238, 150 (1996), (6) A.R. Butler & P. Rhodes; Anal. Biochem. 249, 1 (1997), (7) R. Motterlini, et al.; J. Biol. Chem. 275, 13613 (2000), (8) H. K. Jeon, et al.; Cell. Biol. Toxicol. 21, 115 (2005), (9) C.X. Yu, et al.; Mol. Pharmacol. 68, 847 (2005), (10) M. Khan, et. al.; J. Cereb. Blood Flow Metab. 25, 177 (2005), (11) D. McGrowder, et al.; J. Biosci. 31, 347 (2006), (12) R. Prasad, et al.; Glia 55, 65 (2007), (13) M. Mussbacher, et al.; Sci. Rep. 9, 15403 (2019) |
Quantity | 100 mg, 1 g, Bulk |