Specifications
- Purity
- ≥95% (HPLC)
- Appearance
- White to yellow powder
- Identity
- 1H-NMR
Properties
- Solvents
- DMSO (20 mg/ml) or chloroform.
Category: Phytochemicals
Tetra-O-methylscutellarein is a bioactive component of Siam weed extract. It exhibits anti-inflammatory activity through inhibition of the NF-κB pathway. It suppressed IκB kinase complex alpha/beta (IKKα/β) and Inhibitory-kappa-B-alpha (IκBα), inhibiting p65 translocation and thereby suppressing COX-2 and iNOS expression. This compound is modulating bacterial resistance to antimicrobial drugs most probably via efflux pump inhibition. It also showed anti-mutagenic activity.
Synonyms | Scutellarein tetramethyl ether, 5-Methoxysalvigenin, 4',5,6,7-Tetramethoxyflavone, NSC53908 |
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Purity | ≥95% (HPLC) |
Appearance | White to yellow powder |
CAS-Number | 1168-42-9 |
Molecular Formula | C19H18O6 |
Molecular Weight | 342.3 |
Identity | 1H-NMR |
Solvents | DMSO (20 mg/ml) or chloroform. |
Smiles | O=C(C=C(C1=CC=C(OC)C=C1)O2)C3=C2C=C(OC)C(OC)=C3OC |
InChi Key | URSUMOWUGDXZHU-UHFFFAOYSA-N |
Shipping | AMBIENT |
Short Term Storage | -20°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light and moisture. |
Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Transportation | Not dangerous goods |
References | (1) M. Miyazawa, et al., J. Agric. Food Chem. 47, 5239 (1999), (2) G.L. Maia, et al., Molecules 16, 4828 (2011), (3) H. Pandith, et al., J. Ethnopharmacol. 147, 434 (2013) |
InChi | InChI=1S/C19H18O6/c1-21-12-7-5-11(6-8-12)14-9-13(20)17-15(25-14)10-16(22-2)18(23-3)19(17)24-4/h5-10H,1-4H3 |
Quantity | 1 mg, 5 mg, Bulk |