Specifications
- Purity
- ≥99% (CHN)
- Identity
- 1H-NMR
- Appearance
- Light yellow powder/crystals
Properties
- Melting Point
- 155 - 159 °C
- Solvents
- toluene
Downloads
- Safety Data Sheet
- CDX C0228 MSDS.pdf
Available from stock
(-)-Cytisine
- SKU
- C0228
Category: Phytochemicals
- Synonyms
- NSC 407282 , BRN 0083882 , Baptitoxine , Sophorine , (1S,5R)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one
- 485-35-8
- CAS-Number
- C11H14N2O
- Molecular Formula
- 190.2
- Molecular Weight
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Long Term Storage
- -20°C
- Short Term Storage
- +4°C
- Shipping
- AMBIENT
- Transportation
- Excepted Quantities
- RIDADR
- UN2811 6.1
- Signal word
- Danger
- GHS Symbol
- GHS06
- Precautionary statements
- P261-P301 + P310-P305 + P351 + P338
- Hazard statements
- H301, H315, H319, H335
- Description
- Pyridine-like alkaloid. Nicotine agonist. Potent agonist at alpha3beta4 and alpha7 nicotinic acetylcholine receptors and partial agonist at alpha4beta2 nicotinic acetylcholine receptors. Shows analgesic, antihypertensive and inotropic activities. Used for smoking cessation. Iron-chelator and hydroxyl radical scavanger. Has antidepressant properties. Used in forensics in novel surface molecular imprinting techniques.
- InChi
- InChI=1S/C11H14N2O/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11/h1-3,8-9,12H,4-7H2/t8-,9+/m0/s1
- References
- (1) R.L. Papke & S.F. Heinemann: Mol. Pharmacol. 45, 142 (1994) , (2) B.W. Wenger, et al.: J. Pharmacol. Exp. Ther. 281, 905 (1997) , (3) B. Ferger, et al.: Eur. J. Pharmacol. 360, 155 (1998) , (4) Y.E. Slater, et al.: Neuropharmacology 44, 503 (2003) , (5) P. Tutka & W. Zatonski: Pharmacol. Rep. 58, 777 (2006) (Review) , (6) J.F. Etter, et al.: Drug Alcohol Depend. 92, 3 (2008) (Review) , (7) Y.F. Li, et al.: Auton. Neurosci. 154, 14 (2010) , (8) E.G. Perez, et al.: Nat. Prod. Rep. 29, 555 (2012) (Review)
- InChi Key
- ANJTVLIZGCUXLD-DTWKUNHWSA-N
- Smiles
- O=C1C=CC=C2[C@@H]3CNCC(C3)CN12
Pyridine-like alkaloid. Nicotine agonist. Potent agonist at alpha3beta4 and alpha7 nicotinic acetylcholine receptors and partial agonist at alpha4beta2 nicotinic acetylcholine receptors. Shows analgesic, antihypertensive and inotropic activities. Used for smoking cessation. Iron-chelator and hydroxyl radical scavanger. Has antidepressant properties. Used in forensics in novel surface molecular imprinting techniques.
Additional information
| Synonyms | NSC 407282, BRN 0083882, Baptitoxine, Sophorine, (1S,5R)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one |
|---|---|
| Purity | ≥99% (CHN) |
| Appearance | Light yellow powder/crystals |
| CAS-Number | 485-35-8 |
| Molecular Formula | C11H14N2O |
| Molecular Weight | 190.2 |
| Identity | 1H-NMR |
| Solvents | toluene |
| Melting Point | 155 – 159 °C |
| Smiles | O=C1C=CC=C2[C@@H]3CNCC(C3)CN12 |
| InChi Key | ANJTVLIZGCUXLD-DTWKUNHWSA-N |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Hazard statements | H301, H315, H319, H335 |
| Precautionary statements | P261-P301 + P310-P305 + P351 + P338 |
| GHS Symbol | GHS06 |
| Signal word | Danger |
| RIDADR | UN2811 6.1 |
| Transportation | Excepted Quantities |
| References | (1) R.L. Papke & S.F. Heinemann: Mol. Pharmacol. 45, 142 (1994), (2) B.W. Wenger, et al.: J. Pharmacol. Exp. Ther. 281, 905 (1997), (3) B. Ferger, et al.: Eur. J. Pharmacol. 360, 155 (1998), (4) Y.E. Slater, et al.: Neuropharmacology 44, 503 (2003), (5) P. Tutka & W. Zatonski: Pharmacol. Rep. 58, 777 (2006) (Review), (6) J.F. Etter, et al.: Drug Alcohol Depend. 92, 3 (2008) (Review), (7) Y.F. Li, et al.: Auton. Neurosci. 154, 14 (2010), (8) E.G. Perez, et al.: Nat. Prod. Rep. 29, 555 (2012) (Review) |
| InChi | InChI=1S/C11H14N2O/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11/h1-3,8-9,12H,4-7H2/t8-,9+/m0/s1 |
| Quantity | 100 mg, 500 mg, 5 g, Bulk |
