- Synonyms: (1S,5R)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one, Baptitoxine, BRN 0083882, NSC 407282, Sophorine
- Purity: ≥99% (CHN)
- Appearance: Light yellow powder/crystals.
- CAS-Number: 485-35-8
- Molecular Formula: C11H14N2O
- Molecular Weight: 190.2
- Identity: 1H-NMR
- Solvents: Soluble in toluene.
- Melting Point: 155 - 159 °C
- Smiles: O=C1C=CC=C2[C@@H]3CNCC(C3)CN12
- InChi: InChI=1S/C11H14N2O/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11/h1-3,8-9,12H,4-7H2/t8-,9+/m0/s1
- InChi Key: ANJTVLIZGCUXLD-DTWKUNHWSA-N
Available from stock
(-)-Cytisine
SKU: C0228
Category: Phytochemicals
- Shipping: AMBIENT
- Short Term Storage: +4°C
- Long Term Storage: -20°C
- Handling Advice: Protect from light and moisture. Keep cool and dry.
- Use / Stability: Stable for at least 2 years after receipt when stored at -20°C.
- Description: Pyridine-like alkaloid. Nicotine agonist. Potent agonist at alpha3beta4 and alpha7 nicotinic acetylcholine receptors and partial agonist at alpha4beta2 nicotinic acetylcholine receptors. Shows analgesic, antihypertensive and inotropic activities. Used for smoking cessation. Iron-chelator and hydroxyl radical scavanger. Has antidepressant properties. Used in forensics in novel surface molecular imprinting techniques.
- References: (1) R.L. Papke & S.F. Heinemann; Mol. Pharmacol. 45, 142 (1994), (2) B.W. Wenger, et al.; J. Pharmacol. Exp. Ther. 281, 905 (1997), (3) B. Ferger, et al.; Eur. J. Pharmacol. 360, 155 (1998), (4) Y.E. Slater, et al.; Neuropharmacology 44, 503 (2003), (5) P. Tutka & W. Zatonski; Pharmacol. Rep. 58, 777 (2006) (Review), (6) J.F. Etter, et al.; Drug Alcohol Depend. 92, 3 (2008) (Review), (7) Y.F. Li, et al.; Auton. Neurosci. 154, 14 (2010), (8) E.G. Perez, et al.; Nat. Prod. Rep. 29, 555 (2012) (Review)
Pyridine-like alkaloid. Nicotine agonist. Potent agonist at alpha3beta4 and alpha7 nicotinic acetylcholine receptors and partial agonist at alpha4beta2 nicotinic acetylcholine receptors. Shows analgesic, antihypertensive and inotropic activities. Used for smoking cessation. Iron-chelator and hydroxyl radical scavanger. Has antidepressant properties. Used in forensics in novel surface molecular imprinting techniques.
Additional information
| Quantity | 100 mg, 5 g, 500 mg, Bulk |
|---|---|
| Identity | 1H-NMR |
| Availability | 1 |
| CAS-Number | 485-35-8 |
| InChi | InChI=1S/C11H14N2O/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11/h1-3,8-9,12H,4-7H2/t8-,9+/m0/s1 |
| Molecular Formula | |
| Appearance | Light yellow powder/crystals. |
| InChi Key | ANJTVLIZGCUXLD-DTWKUNHWSA-N |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. Keep cool and dry. |
| Molecular Weight | |
| Short Term Storage | +4°C |
| Pricetable | |
| References | (1) R.L. Papke & S.F. Heinemann; Mol. Pharmacol. 45, 142 (1994), (2) B.W. Wenger, et al.; J. Pharmacol. Exp. Ther. 281, 905 (1997), (3) B. Ferger, et al.; Eur. J. Pharmacol. 360, 155 (1998), (4) Y.E. Slater, et al.; Neuropharmacology 44, 503 (2003), (5) P. Tutka & W. Zatonski; Pharmacol. Rep. 58, 777 (2006) (Review), (6) J.F. Etter, et al.; Drug Alcohol Depend. 92, 3 (2008) (Review), (7) Y.F. Li, et al.; Auton. Neurosci. 154, 14 (2010), (8) E.G. Perez, et al.; Nat. Prod. Rep. 29, 555 (2012) (Review) |
| Shipping | AMBIENT |
| Smiles | O=C1C=CC=C2[C@@H]3CNCC(C3)CN12 |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Purity | |
| Solvents | Soluble in toluene. |
| Synonyms | (1S,5R)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one, Baptitoxine, BRN 0083882, NSC 407282, Sophorine |
| Melting Point | 155 – 159 °C |
Reviews
There are no reviews yet.