Specifications
- Purity
- ≥98%
- Appearance
- Off-white crystalline powder
- Identity
- 1H-NMR
Properties
- Solvents
- ethanol (30 mg/ml), DMSO, DMF
Available from stock
trans-11-methyl-2-dodecenoic acid
- SKU
- D0791
Category: Quorum Sensing
- Synonyms
- trans-DSF , trans-δ2-11-methyl-dodecenoic , 11-Methyl-2-trans-Dodecenoic acid , 11-methyl-2E-dodecenoic acid
- 677354-24-4
- CAS-Number
- C13H24O2
- Molecular Formula
- 212.3
- Molecular Weight
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
- Shipping
- AMBIENT
- Short Term Storage
- -20°C
- Long Term Storage
- -20°C
- Handling Advice
- Protect from light and moisture.
- Use / Stability
- Stable for at least 2 years after receipt when stored at -20°C.
- Transportation
- Not dangerous goods
- Description
- trans-δ2-11-methyl-Dodecenoic acid is the conformational isomer of cis-δ2-11-methyl-dodecenoic acid, a diffusible signal factor (DSF) in extracellular microbial and fungal communication systems. Both prokaryotes and eukaryotes depend on small signalling molecules for cell-cell communication. In a DSF bioassay, the minimum concentration of cis-δ2-11-methyl-dodecenoic acid required for induction of a DSF biosensor was about 0.5 µM, which is 200-fold lower than that of trans-δ2-11-methyl-dodecenoic acid and 20,000-fold lower than that of the corresponding saturated fatty acid (11-methyl-dodecanoic acid).
- Smiles
- CC(C)CCCCCCC/C=C/C(O)=O
- InChi Key
- SNTXNGAQYNSTHI-PKNBQFBNSA-N
- References
- (1) L.H. Wang, et al., Mol. Microbiol. 51, 903 (2004) , (2) K.B. Twomey, et al., ISME J. 6, 939 (2012)
- InChi
- InChI=1S/C13H24O2/c1-12(2)10-8-6-4-3-5-7-9-11-13(14)15/h9,11-12H,3-8,10H2,1-2H3,(H,14,15)/b11-9+
trans-δ2-11-methyl-Dodecenoic acid is the conformational isomer of cis-δ2-11-methyl-dodecenoic acid, a diffusible signal factor (DSF) in extracellular microbial and fungal communication systems. Both prokaryotes and eukaryotes depend on small signalling molecules for cell-cell communication. In a DSF bioassay, the minimum concentration of cis-δ2-11-methyl-dodecenoic acid required for induction of a DSF biosensor was about 0.5 µM, which is 200-fold lower than that of trans-δ2-11-methyl-dodecenoic acid and 20,000-fold lower than that of the corresponding saturated fatty acid (11-methyl-dodecanoic acid).
Additional information
| Synonyms | trans-DSF, trans-δ2-11-methyl-dodecenoic, 11-Methyl-2-trans-Dodecenoic acid, 11-methyl-2E-dodecenoic acid |
|---|---|
| Purity | ≥98% |
| Appearance | Off-white crystalline powder |
| CAS-Number | 677354-24-4 |
| Molecular Formula | C13H24O2 |
| Molecular Weight | 212.3 |
| Identity | 1H-NMR |
| Solvents | ethanol (30 mg/ml), DMSO, DMF |
| Smiles | CC(C)CCCCCCC/C=C/C(O)=O |
| InChi Key | SNTXNGAQYNSTHI-PKNBQFBNSA-N |
| Shipping | AMBIENT |
| Short Term Storage | -20°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use / Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Transportation | Not dangerous goods |
| References | (1) L.H. Wang, et al., Mol. Microbiol. 51, 903 (2004), (2) K.B. Twomey, et al., ISME J. 6, 939 (2012) |
| InChi | InChI=1S/C13H24O2/c1-12(2)10-8-6-4-3-5-7-9-11-13(14)15/h9,11-12H,3-8,10H2,1-2H3,(H,14,15)/b11-9+ |
| Quantity | 5 mg, 25 mg, Bulk |
